5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers
Noordhuis, P., Holwerda, U., Van der Wilt, C. L., Van Groeningen, C. J., Smid, K., Meijer, S., Pinedo, H. M., Peters, G. J.
Published in Annals of oncology (01.07.2004)
Published in Annals of oncology (01.07.2004)
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Phase II study of tailored chemotherapy for advanced colorectal cancer with either 5-fluouracil and leucovorin or oxaliplatin and irinotecan based on the expression of thymidylate synthase and dihydropyrimidine dehydrogenase
Smorenburg, C. H., Peters, G. J., van Groeningen, C. J., Noordhuis, P., Smid, K., van Riel, A. M. G. H., Dercksen, W., Pinedo, H. M., Giaccone, G.
Published in Annals of oncology (01.01.2006)
Published in Annals of oncology (01.01.2006)
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Clinical phase I and pharmacology study of gemcitabine (2', 2'-difluorodeoxycytidine) administered in a two-weekly schedule
Peters, G J, Clavel, M, Noordhuis, P, Geyssen, G J, Laan, A C, Guastalla, J, Edzes, H T, Vermorken, J B
Published in Journal of chemotherapy (Florence) (01.04.2007)
Published in Journal of chemotherapy (Florence) (01.04.2007)
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mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method
ROTS, M. G, WILLEY, J. C, JANSEN, G, VAN ZANTWIJK, C. H, NOORDHUIS, P, DEMUTH, J. P, KUIPER, E, VEERMAN, A. J. P, PIETERS, R, PETERS, G. I
Published in Leukemia (01.12.2000)
Published in Leukemia (01.12.2000)
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The role of thymidine phosphorylase and uridine phosphorylase in (fluoro)pyrimidine metabolism in peripheral blood mononuclear cells
Temmink, O.H., de Bruin, M., Laan, A.C., Turksma, A.W., Cricca, S., Masterson, A.J., Noordhuis, P., Peters, G.J.
Published in The international journal of biochemistry & cell biology (2006)
Published in The international journal of biochemistry & cell biology (2006)
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Selective Protection by Uridine of Growth Inhibition by 5-Fluorouracil (5FU) Mediated by 5FU Incorporation into RNA, But Not the Thymidylate Synthase Mediated Growth Inhibition by 5FU-Leucovorin
Codacci-Pisanelli, G., Noordhuis, P., van der Wilt, C. L., Peters, G. J.
Published in Nucleosides, nucleotides & nucleic acids (01.06.2008)
Published in Nucleosides, nucleotides & nucleic acids (01.06.2008)
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Rapid disappearance of deoxyribose-1-phosphate in platelet derived endothelial cell growth factor/thymidine phosphorylase overexpressing cells
de Bruin, M, Smid, K, Laan, A.C, Noordhuis, P, Fukushima, M, Hoekman, K, Pinedo, H.M, Peters, G.J
Published in Biochemical and biophysical research communications (14.02.2003)
Published in Biochemical and biophysical research communications (14.02.2003)
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Pharmacokinetics of S-1, an oral formulation of ftorafur, oxonic acid and 5-chloro-2,4-dihydroxypyridine (molar ratio 1:0.4:1) in patients with solid tumors
PETERS, G. J, NOORDHUIS, P, HOLWERDA, U, GIACCONE, K. Smid G, FUMOLEAU, P, VAN GROENINGEN, C. J, VAN KUILENBURG, A. B. P, SCHORNAGEL, J. H, GALL, H, TURNER, S. L, SWART, M. S, VOORN, D, VAN GENNIP, A. H, WANDERS, J
Published in Cancer chemotherapy and pharmacology (01.07.2003)
Published in Cancer chemotherapy and pharmacology (01.07.2003)
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Cross-resistance in the 2′,2′-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000 to standard and investigational drugs
Bergman, A.M., Giaccone, G., van Moorsel, C.J.A., Mauritz, R., Noordhuis, P., Pinedo, H.M., Peters, G.J.
Published in European journal of cancer (1990) (01.10.2000)
Published in European journal of cancer (1990) (01.10.2000)
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A possible role for methotrexate in the treatment of childhood acute myeloid leukaemia, in particular for acute monocytic leukaemia
Rots, M.G., Pieters, R., Jansen, G., Kaspers, G.J.L., Van Zantwijk, C.H., Noordhuis, P., Voorn, D.A., Van Wering, E.R., Creutzig, U., Veerman, A.J.P., Peters, G.J.
Published in European journal of cancer (1990) (01.03.2001)
Published in European journal of cancer (1990) (01.03.2001)
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Comparison of mRNA Expression Levels Determined with TAQ-Man and Competitive Template RT-PCR
Mauritz, R., Schwabe, W., Haeusler, P., Noordhuis, P., Smid, K., McLeod, H. L., Behnke, D., van Groeningen, C. J., Peters, G. J.
Published in Nucleosides, nucleotides & nucleic acids (31.12.2004)
Published in Nucleosides, nucleotides & nucleic acids (31.12.2004)
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Infants with acute lymphoblastic leukemia: no evidence for high methotrexate resistance
Ramakers-van Woerden, N L, Pieters, R, Rots, M G, van Zantwijk, C H, Noordhuis, P, Beverloo, H B, Peters, G J, van Wering, E R, Camitta, B M, Pui, C-H, Relling, M V, Evans, W E, Veerman, A J P
Published in Leukemia (01.05.2002)
Published in Leukemia (01.05.2002)
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Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma
Peters, G J, Lankelma, J, Kok, R M, Noordhuis, P, van Groeningen, C J, van der Wilt, C L, Meyer, S, Pinedo, H M
Published in Cancer chemotherapy and pharmacology (01.01.1993)
Published in Cancer chemotherapy and pharmacology (01.01.1993)
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Transformation of mouse fibroblasts with the oncogenes H-ras OR trk is associated with pronounced changes in drug sensitivity and metabolism
Peters, G J, Wets, M, Keepers, Y P, Oskam, R, van Ark-Otte, J, Noordhuis, P, Smid, K, Pinedo, H M
Published in International journal of cancer (28.05.1993)
Published in International journal of cancer (28.05.1993)
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Issues of Normal Tissue Toxicity in Patient and Animal Studies - Effect of Carbogen Breathing in Rats after 5-Fluorouracil Treatment
GRIFFITHS, John R, MCINTYRE, Dominick J. O, SMID, Kees, NOORDHUIS, Paul, PETERS, Godefridus J, STUBBS, Marion, HOWE, Franklyn A, MCSHEEHY, Paul M. J, OJUGO, Agatha S. E, RODRIGUES, Loreta M, WADSWORTH, Peter, PRICE, Natasha M, LOFTS, Fiona, NICHOLSON, Grainne
Published in Acta oncologica (2001)
Published in Acta oncologica (2001)
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Therapeutic efficacy of fluoropyrimidines depends on the duration of thymidylate synthase inhibition in the murine colon 26-B carcinoma tumor model
VAN LAAR, J. A. M, VAN DER WILT, C. L, RUSTUM, Y. M, NOORDHUIS, P, SMID, K, PINEDO, H. M, PETERS, G. J
Published in Clinical cancer research (01.08.1996)
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Published in Clinical cancer research (01.08.1996)
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Similar changes were induced by Cladribine and by gemcitabine, in the deoxypyrimidine salvage, during short-term treatments
Csapó, Z, Keszler, G, Sasvári-Székely, M, Smid, K, Noordhuis, P, Peters, G J, Staub, M
Published in Advances in experimental medicine and biology (1998)
Published in Advances in experimental medicine and biology (1998)
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