Cancer Metabolism: Current Understanding and Therapies
Counihan, Jessica L, Grossman, Elizabeth A, Nomura, Daniel K
Published in Chemical reviews (25.07.2018)
Published in Chemical reviews (25.07.2018)
Get full text
Journal Article
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
Bersuker, Kirill, Hendricks, Joseph M., Li, Zhipeng, Magtanong, Leslie, Ford, Breanna, Tang, Peter H., Roberts, Melissa A., Tong, Bingqi, Maimone, Thomas J., Zoncu, Roberto, Bassik, Michael C., Nomura, Daniel K., Dixon, Scott J., Olzmann, James A.
Published in Nature (London) (01.11.2019)
Published in Nature (London) (01.11.2019)
Get full text
Journal Article
Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function
Valdearcos, Martin, Robblee, Megan M., Benjamin, Daniel I., Nomura, Daniel K., Xu, Allison W., Koliwad, Suneil K.
Published in Cell reports (Cambridge) (24.12.2014)
Published in Cell reports (Cambridge) (24.12.2014)
Get full text
Journal Article
Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
Camarda, Roman, Zhou, Alicia Y, Kohnz, Rebecca A, Balakrishnan, Sanjeev, Mahieu, Celine, Anderton, Brittany, Eyob, Henok, Kajimura, Shingo, Tward, Aaron, Krings, Gregor, Nomura, Daniel K, Goga, Andrei
Published in Nature medicine (01.04.2016)
Published in Nature medicine (01.04.2016)
Get full text
Journal Article
Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications
Henning, Nathaniel J, Manford, Andrew G, Spradlin, Jessica N, Brittain, Scott M, Zhang, Erika, McKenna, Jeffrey M, Tallarico, John A, Schirle, Markus, Rape, Michael, Nomura, Daniel K
Published in Journal of the American Chemical Society (19.01.2022)
Published in Journal of the American Chemical Society (19.01.2022)
Get full text
Journal Article
Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism
Nikkanen, Joni, Forsström, Saara, Euro, Liliya, Paetau, Ilse, Kohnz, Rebecca A., Wang, Liya, Chilov, Dmitri, Viinamäki, Jenni, Roivainen, Anne, Marjamäki, Päivi, Liljenbäck, Heidi, Ahola, Sofia, Buzkova, Jana, Terzioglu, Mügen, Khan, Nahid A., Pirnes-Karhu, Sini, Paetau, Anders, Lönnqvist, Tuula, Sajantila, Antti, Isohanni, Pirjo, Tyynismaa, Henna, Nomura, Daniel K., Battersby, Brendan J., Velagapudi, Vidya, Carroll, Christopher J., Suomalainen, Anu
Published in Cell metabolism (12.04.2016)
Published in Cell metabolism (12.04.2016)
Get full text
Journal Article
Activity-based protein profiling for biochemical pathway discovery in cancer
Cravatt, Benjamin F, Nomura, Daniel K, Dix, Melissa M
Published in Nature reviews. Cancer (01.09.2010)
Published in Nature reviews. Cancer (01.09.2010)
Get full text
Journal Article
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation
Spradlin, Jessica N., Hu, Xirui, Ward, Carl C., Brittain, Scott M., Jones, Michael D., Ou, Lisha, To, Milton, Proudfoot, Andrew, Ornelas, Elizabeth, Woldegiorgis, Mikias, Olzmann, James A., Bussiere, Dirksen E., Thomas, Jason R., Tallarico, John A., McKenna, Jeffrey M., Schirle, Markus, Maimone, Thomas J., Nomura, Daniel K.
Published in Nature chemical biology (01.07.2019)
Published in Nature chemical biology (01.07.2019)
Get full text
Journal Article
Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism
Lee, Jiyoung, Yesilkanal, Ali E., Wynne, Joseph P., Frankenberger, Casey, Liu, Juan, Yan, Jielin, Elbaz, Mohamad, Rabe, Daniel C., Rustandy, Felicia D., Tiwari, Payal, Grossman, Elizabeth A., Hart, Peter C., Kang, Christie, Sanderson, Sydney M., Andrade, Jorge, Nomura, Daniel K., Bonini, Marcelo G., Locasale, Jason W., Rosner, Marsha Rich
Published in Nature (London) (01.04.2019)
Published in Nature (London) (01.04.2019)
Get full text
Journal Article
A Cellular Mechanism to Detect and Alleviate Reductive Stress
Manford, Andrew G., Rodríguez-Pérez, Fernando, Shih, Karen Y., Shi, Zhuo, Berdan, Charles A., Choe, Mangyu, Titov, Denis V., Nomura, Daniel K., Rape, Michael
Published in Cell (01.10.2020)
Published in Cell (01.10.2020)
Get full text
Journal Article
Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
Castellano, Brian M., Thelen, Ashley M., Moldavski, Ofer, Feltes, McKenna, van der Welle, Reini E. N., Mydock-McGrane, Laurel, Jiang, Xuntian, van Eijkeren, Robert J, Davis, Oliver B., Louie, Sharon M., Perera, Rushika M., Covey, Douglas F., Nomura, Daniel K., Ory, Daniel S., Zoncu, Roberto
Published in Science (American Association for the Advancement of Science) (24.03.2017)
Published in Science (American Association for the Advancement of Science) (24.03.2017)
Get full text
Journal Article
Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition
Chung, Clive Yik-Sham, Shin, Hijai R., Berdan, Charles A., Ford, Breanna, Ward, Carl C., Olzmann, James A., Zoncu, Roberto, Nomura, Daniel K.
Published in Nature chemical biology (01.08.2019)
Published in Nature chemical biology (01.08.2019)
Get full text
Journal Article
Bardoxolone conjugation enables targeted protein degradation of BRD4
Tong, Bingqi, Luo, Mai, Xie, Yi, Spradlin, Jessica N., Tallarico, John A., McKenna, Jeffrey M., Schirle, Markus, Maimone, Thomas J., Nomura, Daniel K.
Published in Scientific reports (23.09.2020)
Published in Scientific reports (23.09.2020)
Get full text
Journal Article
Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications
Ward, Carl C, Kleinman, Jordan I, Brittain, Scott M, Lee, Patrick S, Chung, Clive Yik Sham, Kim, Kenneth, Petri, Yana, Thomas, Jason R, Tallarico, John A, McKenna, Jeffrey M, Schirle, Markus, Nomura, Daniel K
Published in ACS chemical biology (15.11.2019)
Published in ACS chemical biology (15.11.2019)
Get full text
Journal Article
Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer
Watt, Matthew J, Clark, Ashlee K, Selth, Luke A, Haynes, Vanessa R, Lister, Natalie, Rebello, Richard, Porter, Laura H, Niranjan, Birunthi, Whitby, Sarah T, Lo, Jennifer, Huang, Cheng, Schittenhelm, Ralf B, Anderson, Kimberley E, Furic, Luc, Wijayaratne, Poornima R, Matzaris, Maria, Montgomery, Magdalene K, Papargiris, Melissa, Norden, Sam, Febbraio, Maria, Risbridger, Gail P, Frydenberg, Mark, Nomura, Daniel K, Taylor, Renea A
Published in Science translational medicine (06.02.2019)
Published in Science translational medicine (06.02.2019)
Get more information
Journal Article
GSTP1 Is a Driver of Triple-Negative Breast Cancer Cell Metabolism and Pathogenicity
Louie, Sharon M., Grossman, Elizabeth A., Crawford, Lisa A., Ding, Lucky, Camarda, Roman, Huffman, Tucker R., Miyamoto, David K., Goga, Andrei, Weerapana, Eranthie, Nomura, Daniel K.
Published in Cell chemical biology (19.05.2016)
Published in Cell chemical biology (19.05.2016)
Get full text
Journal Article
Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC
Boike, Lydia, Cioffi, Alexander G., Majewski, Felix C., Co, Jennifer, Henning, Nathaniel J., Jones, Michael D., Liu, Gang, McKenna, Jeffrey M., Tallarico, John A., Schirle, Markus, Nomura, Daniel K.
Published in Cell chemical biology (21.01.2021)
Published in Cell chemical biology (21.01.2021)
Get full text
Journal Article