Immunomodulatory activity of lenvatinib contributes to antitumor activity in the Hepa1‐6 hepatocellular carcinoma model
Kimura, Takayuki, Kato, Yu, Ozawa, Yoichi, Kodama, Kotaro, Ito, Junichi, Ichikawa, Kenji, Yamada, Kazuhiko, Hori, Yusaku, Tabata, Kimiyo, Takase, Kazuma, Matsui, Junji, Funahashi, Yasuhiro, Nomoto, Kenichi
Published in Cancer science (01.12.2018)
Published in Cancer science (01.12.2018)
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Lenvatinib plus anti-PD-1 antibody combination treatment activates CD8+ T cells through reduction of tumor-associated macrophage and activation of the interferon pathway
Kato, Yu, Tabata, Kimiyo, Kimura, Takayuki, Yachie-Kinoshita, Ayako, Ozawa, Yoichi, Yamada, Kazuhiko, Ito, Junichi, Tachino, Sho, Hori, Yusaku, Matsuki, Masahiro, Matsuoka, Yukiko, Ghosh, Samik, Kitano, Hiroaki, Nomoto, Kenichi, Matsui, Junji, Funahashi, Yasuhiro
Published in PloS one (27.02.2019)
Published in PloS one (27.02.2019)
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Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models
Funahashi, Yasuhiro, Okamoto, Kiyoshi, Adachi, Yusuke, Semba, Taro, Uesugi, Mai, Ozawa, Yoichi, Tohyama, Osamu, Uehara, Taisuke, Kimura, Takayuki, Watanabe, Hideki, Asano, Makoto, Kawano, Satoshi, Tizon, Xavier, McCracken, Paul J., Matsui, Junji, Aoshima, Ken, Nomoto, Kenichi, Oda, Yoshiya
Published in Cancer science (01.10.2014)
Published in Cancer science (01.10.2014)
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Lenvatinib induces death of human hepatocellular carcinoma cells harboring an activated FGF signaling pathway through inhibition of FGFR–MAPK cascades
Hoshi, Taisuke, Watanabe Miyano, Saori, Watanabe, Hideki, Sonobe, Regina Mikie Kanada, Seki, Yuki, Ohta, Etsuko, Nomoto, Kenichi, Matsui, Junji, Funahashi, Yasuhiro
Published in Biochemical and biophysical research communications (21.05.2019)
Published in Biochemical and biophysical research communications (21.05.2019)
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Journal Article
The Connection between Gamma-Ray Bursts and Extremely Metal-poor Stars: Black Hole-forming Supernovae with Relativistic Jets
Tominaga, Nozomu, Maeda, Keiichi, Umeda, Hideyuki, Nomoto, Ken’ichi, Tanaka, Masaomi, Iwamoto, Nobuyuki, Suzuki, Tomoharu, Mazzali, Paolo A
Published in The Astrophysical journal (10.03.2007)
Published in The Astrophysical journal (10.03.2007)
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High absolute lymphocyte counts are associated with longer overall survival in patients with metastatic breast cancer treated with eribulin—but not with treatment of physician’s choice—in the EMBRACE study
Miyoshi, Yasuo, Yoshimura, Yuta, Saito, Kenichi, Muramoto, Kenzo, Sugawara, Michiko, Alexis, Karenza, Nomoto, Kenichi, Nakamura, Seigo, Saeki, Toshiaki, Watanabe, Junichiro, Perez-Garcia, Jose Manuel, Cortes, Javier
Published in Breast cancer (Tokyo, Japan) (01.07.2020)
Published in Breast cancer (Tokyo, Japan) (01.07.2020)
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Peripheral Neuropathy Induced by Microtubule-Targeted Chemotherapies: Insights into Acute Injury and Long-term Recovery
Wozniak, Krystyna M, Vornov, James J, Wu, Ying, Liu, Ying, Carozzi, Valentina A, Rodriguez-Menendez, Virginia, Ballarini, Elisa, Alberti, Paola, Pozzi, Eleonora, Semperboni, Sara, Cook, Brett M, Littlefield, Bruce A, Nomoto, Kenichi, Condon, Krista, Eckley, Sean, DesJardins, Christopher, Wilson, Leslie, Jordan, Mary A, Feinstein, Stuart C, Cavaletti, Guido, Polydefkis, Michael, Slusher, Barbara S
Published in Cancer research (Chicago, Ill.) (01.02.2018)
Published in Cancer research (Chicago, Ill.) (01.02.2018)
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The Dual MEK/FLT3 Inhibitor E6201 Exerts Cytotoxic Activity against Acute Myeloid Leukemia Cells Harboring Resistance-Conferring FLT3 Mutations
Zhang, Weiguo, Borthakur, Gautam, Gao, Chen, Chen, Ye, Mu, Hong, Ruvolo, Vivian R, Nomoto, Kenichi, Zhao, Nanding, Konopleva, Marina, Andreeff, Michael
Published in Cancer research (Chicago, Ill.) (15.03.2016)
Published in Cancer research (Chicago, Ill.) (15.03.2016)
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Journal Article
Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61
Huang, Kuan-Chun, Chen, Zhihong, Jiang, Yimin, Akare, Sandeep, Kolber-Simonds, Donna, Condon, Krista, Agoulnik, Sergei, Tendyke, Karen, Shen, Yongchun, Wu, Kuo-Ming, Mathieu, Steven, Choi, Hyeong-Wook, Zhu, Xiaojie, Shimizu, Hajime, Kotake, Yoshihiko, Gerwick, William H, Uenaka, Toshimitsu, Woodall-Jappe, Mary, Nomoto, Kenichi
Published in Molecular cancer therapeutics (01.06.2016)
Published in Molecular cancer therapeutics (01.06.2016)
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E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling
McGonigle, Sharon, Chen, Zhihong, Wu, Jiayi, Chang, Paul, Kolber-Simonds, Donna, Ackermann, Karen, Twine, Natalie C, Shie, Jue-Lon, Miu, Jingzang Tao, Huang, Kuan-Chun, Moniz, George A, Nomoto, Kenichi
Published in Oncotarget (01.12.2015)
Published in Oncotarget (01.12.2015)
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EP4 Antagonism by E7046 diminishes Myeloid immunosuppression and synergizes with Treg-reducing IL-2-Diphtheria toxin fusion protein in restoring anti-tumor immunity
Albu, Diana I., Wang, Zichun, Huang, Kuan-Chun, Wu, Jiayi, Twine, Natalie, Leacu, Sarah, Ingersoll, Christy, Parent, Lana, Lee, Winnie, Liu, Diana, Wright-Michaud, Renee, Kumar, Namita, Kuznetsov, Galina, Chen, Qian, Zheng, Wanjun, Nomoto, Kenichi, Woodall-Jappe, Mary, Bao, Xingfeng
Published in Oncoimmunology (03.08.2017)
Published in Oncoimmunology (03.08.2017)
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Journal Article
Comparison of Neuropathy-Inducing Effects of Eribulin Mesylate, Paclitaxel, and Ixabepilone in Mice
WOZNIAK, Krystyna M, NOMOTO, Kenichi, SLUSHER, Barbara S, LAPIDUS, Rena G, YING WU, CAROZZI, Valentina, CAVALETTI, Guido, HAYAKAWA, Kazuhiro, HOSOKAWA, Satoru, TOWLE, Murray J, LITTLEFIELD, Bruce A
Published in Cancer research (Chicago, Ill.) (01.06.2011)
Published in Cancer research (Chicago, Ill.) (01.06.2011)
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Journal Article
Three-dimensional Simulation of Double Detonations in the Double-degenerate Model for Type Ia Supernovae and Interaction of Ejecta with a Surviving White Dwarf Companion
Tanikawa, Ataru, Nomoto, Ken'ichi, Nakasato, Naohito
Published in The Astrophysical journal (01.12.2018)
Published in The Astrophysical journal (01.12.2018)
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Journal Article
Pulsational Pair-instability Supernovae. I. Pre-collapse Evolution and Pulsational Mass Ejection
Leung, Shing-Chi, Nomoto, Ken'ichi, Blinnikov, Sergei
Published in The Astrophysical journal (10.12.2019)
Published in The Astrophysical journal (10.12.2019)
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Journal Article
The Initial Mass Function of the First Stars Inferred from Extremely Metal-poor Stars
Ishigaki, Miho N., Tominaga, Nozomu, Kobayashi, Chiaki, Nomoto, Ken'ichi
Published in The Astrophysical journal (10.04.2018)
Published in The Astrophysical journal (10.04.2018)
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Journal Article
Recent advances of MEK inhibitors and their clinical progress
Wang, John Yuan, Wilcoxen, Keith M, Nomoto, Kenichi, Wu, Sara
Published in Current topics in medicinal chemistry (01.07.2007)
Published in Current topics in medicinal chemistry (01.07.2007)
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Journal Article
A Model for the Fast Blue Optical Transient AT2018cow: Circumstellar Interaction of a Pulsational Pair-instability Supernova
Leung, Shing-Chi, Blinnikov, Sergei, Nomoto, Ken'ichi, Baklanov, Petr, Sorokina, Elena, Tolstov, Alexey
Published in The Astrophysical journal (01.11.2020)
Published in The Astrophysical journal (01.11.2020)
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