Synthesis and evaluation of novel dual BRD4/HDAC inhibitors
Amemiya, Seika, Yamaguchi, Takao, Hashimoto, Yuichi, Noguchi-Yachide, Tomomi
Published in Bioorganic & medicinal chemistry (15.07.2017)
Published in Bioorganic & medicinal chemistry (15.07.2017)
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Design, synthesis and structure–activity relationship of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxyisoprop-2-yl)phenylsilane derivatives as liver X receptor agonists
Namba, Nao, Noguchi-Yachide, Tomomi, Matsumoto, Yuichiro, Hashimoto, Yuichi, Fujii, Shinya
Published in Bioorganic & medicinal chemistry (15.07.2022)
Published in Bioorganic & medicinal chemistry (15.07.2022)
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Image-based screen capturing misfolding status of Niemann-Pick type C1 identifies potential candidates for chaperone drugs
Shioi, Ryuta, Karaki, Fumika, Yoshioka, Hiromasa, Noguchi-Yachide, Tomomi, Ishikawa, Minoru, Dodo, Kosuke, Hashimoto, Yuichi, Sodeoka, Mikiko, Ohgane, Kenji
Published in PloS one (14.12.2020)
Published in PloS one (14.12.2020)
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Structure–Activity Relationship Study of N6-Benzoyladenine-Type BRD4 Inhibitors and Their Effects on Cell Differentiation and TNF-α Production
Amemiya, Seika, Yamaguchi, Takao, Sakai, Taki, Hashimoto, Yuichi, Noguchi-Yachide, Tomomi
Published in Chemical & pharmaceutical bulletin (01.09.2016)
Published in Chemical & pharmaceutical bulletin (01.09.2016)
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Phenanthridin-6-one derivatives as the first class of non-steroidal pharmacological chaperones for Niemann-Pick disease type C1 protein
Fukuda, Hiromitsu, Karaki, Fumika, Dodo, Kosuke, Noguchi-Yachide, Tomomi, Ishikawa, Minoru, Hashimoto, Yuichi, Ohgane, Kenji
Published in Bioorganic & medicinal chemistry letters (15.06.2017)
Published in Bioorganic & medicinal chemistry letters (15.06.2017)
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Structural Development of Liver X Receptor (LXR) Antagonists Derived from Thalidomide-Related Glucosidase Inhibitors
Noguchi-Yachide, Tomomi, Miyachi, Hiroyuki, Aoyama, Hiroshi, Aoyama, Atsushi, Makishima, Makoto, Hashimoto, Yuichi
Published in Chemical & Pharmaceutical Bulletin (01.12.2007)
Published in Chemical & Pharmaceutical Bulletin (01.12.2007)
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Development of Tubulin-Polymerization Inhibitors Based on the Thalidomide Skeleton
Aoyama, Hiroshi, Noguchi, Tomomi, Misawa, Takashi, Nakamura, Takanori, Miyachi, Hiroyuki, Hashimoto, Yuichi, Kobayashi, Hisayoshi
Published in Chemical & Pharmaceutical Bulletin (01.06.2007)
Published in Chemical & Pharmaceutical Bulletin (01.06.2007)
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Small-molecular inhibitors of Ca2+-induced mitochondrial permeability transition (MPT) derived from muscle relaxant dantrolene
Murasawa, Shinpei, Iuchi, Katsuya, Sato, Shinichi, Noguchi-Yachide, Tomomi, Sodeoka, Mikiko, Yokomatsu, Tsutomu, Dodo, Kosuke, Hashimoto, Yuichi, Aoyama, Hiroshi
Published in Bioorganic & medicinal chemistry (01.11.2012)
Published in Bioorganic & medicinal chemistry (01.11.2012)
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Antiproliferative and apoptosis-inducing activities of alkyl gallate and gallamide derivatives related to (−)-epigallocatechin gallate
Dodo, Kosuke, Minato, Taro, Noguchi-Yachide, Tomomi, Suganuma, Masami, Hashimoto, Yuichi
Published in Bioorganic & medicinal chemistry (01.09.2008)
Published in Bioorganic & medicinal chemistry (01.09.2008)
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Effects of alkyl side chains and terminal hydrophilicity on vitamin D receptor (VDR) agonistic activity based on the diphenylpentane skeleton
Misawa, Takashi, Yorioka, Momoko, Demizu, Yosuke, Noguchi-Yachide, Tomomi, Ohoka, Nobumichi, Kurashima-Kinoshita, Megumi, Motoyoshi, Hitomi, Nojiri, Hisao, Kittaka, Atsushi, Makishima, Makoto, Naito, Mikihiko, Kurihara, Masaaki
Published in Bioorganic & medicinal chemistry letters (15.11.2015)
Published in Bioorganic & medicinal chemistry letters (15.11.2015)
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