Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2‐Benzyl‐5‐nitroindazole‐Derived Amines
Fonseca‐Berzal, Cristina, Ibáñez‐Escribano, Alexandra, Vela, Nerea, Cumella, José, Nogal‐Ruiz, Juan José, Escario, José Antonio, da Silva, Patrícia Bernardino, Batista, Marcos Meuser, Soeiro, Maria de Nazaré C., Sifontes‐Rodríguez, Sergio, Meneses‐Marcel, Alfredo, Gómez‐Barrio, Alicia, Arán, Vicente J.
Published in ChemMedChem (20.06.2018)
Published in ChemMedChem (20.06.2018)
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Validation of a modified fluorimetric assay for the screening of trichomonacidal drugs
Escribano, Alexandra Ibáñez, Marcel, Alfredo Meneses, Tugores, Yanetsy Machado, Ruiz, Juan José Nogal, Redó, Vicente J Arán, García-Trevijano, José Antonio Escario, Barrio, Alicia Gómez
Published in Memórias do Instituto Oswaldo Cruz (01.08.2012)
Published in Memórias do Instituto Oswaldo Cruz (01.08.2012)
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Journal Article
Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles
Ibáñez-Escribano, Alexandra, Reviriego, Felipe, Vela, Nerea, Fonseca-Berzal, Cristina, Nogal-Ruiz, Juan José, Arán, Vicente J., Escario, José Antonio, Gómez-Barrio, Alicia
Published in Bioorganic & medicinal chemistry letters (01.04.2021)
Published in Bioorganic & medicinal chemistry letters (01.04.2021)
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Journal Article
Synthesis and Evaluation of 1,1′-Hydrocarbylenebis(indazol-3-ols) as Potential Antimalarial Drugs
Martins Alho, Miriam, García-Sánchez, Rory N., Nogal-Ruiz, Juan José, Escario, José Antonio, Gómez-Barrio, Alicia, Martínez-Fernández, Antonio R., Arán, Vicente J.
Published in ChemMedChem (12.01.2009)
Published in ChemMedChem (12.01.2009)
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Journal Article
In vitro trichomonacidal activity and preliminary in silico chemometric studies of 5-nitroindazolin-3-one and 3-alkoxy-5-nitroindazole derivatives
IBÁÑEZ-ESCRIBANO, ALEXANDRA, NOGAL-RUIZ, JUAN JOSÉ, GÓMEZ-BARRIO, ALICIA, ARÁN, VICENTE J., ESCARIO, JOSÉ ANTONIO
Published in Parasitology (01.01.2016)
Published in Parasitology (01.01.2016)
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Journal Article
A sequential procedure for rapid and accurate identification of putative trichomonacidal agents
Ibáñez-Escribano, Alexandra, Meneses-Marcel, Alfredo, Marrero-Ponce, Yovani, Nogal-Ruiz, Juan José, Arán, Vicente J., Gómez-Barrio, Alicia, Escario, José Antonio
Published in Journal of microbiological methods (01.10.2014)
Published in Journal of microbiological methods (01.10.2014)
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A linear discrimination analysis based virtual screening of trichomonacidal lead-like compounds: Outcomes of in silico studies supported by experimental results
Meneses-Marcel, Alfredo, Marrero-Ponce, Yovani, Machado-Tugores, Yanetsy, Montero-Torres, Alina, Pereira, David Montero, Escario, José Antonio, Nogal-Ruiz, Juan José, Ochoa, Carmen, Arán, Vicente J., Martínez-Fernández, Antonio R., García Sánchez, Rory N.
Published in Bioorganic & medicinal chemistry letters (01.09.2005)
Published in Bioorganic & medicinal chemistry letters (01.09.2005)
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Journal Article
Predicting antitrichomonal activity: A computational screening using atom-based bilinear indices and experimental proofs
Marrero-Ponce, Yovani, Meneses-Marcel, Alfredo, Castillo-Garit, Juan A., Machado-Tugores, Yanetsy, Escario, José Antonio, Barrio, Alicia Gómez, Pereira, David Montero, Nogal-Ruiz, Juan José, Arán, Vicente J., Martínez-Fernández, Antonio R., Torrens, Francisco, Rotondo, Richard, Ibarra-Velarde, Froylán, Alvarado, Ysaias J.
Published in Bioorganic & medicinal chemistry (01.10.2006)
Published in Bioorganic & medicinal chemistry (01.10.2006)
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Journal Article
Determination of internal transcribed spacer regions (ITS) in Trichomonas vaginalis isolates and differentiation among Trichomonas species
Ibáñez-Escribano, Alexandra, Nogal-Ruiz, Juan José, Arán, Vicente J, Escario, José Antonio, Gómez-Barrio, Alicia, Alderete, J.F
Published in Parasitology international (01.04.2014)
Published in Parasitology international (01.04.2014)
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Journal Article
Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles
Fonseca-Berzal, Cristina, Ibáñez-Escribano, Alexandra, Reviriego, Felipe, Cumella, José, Morales, Paula, Jagerovic, Nadine, Nogal-Ruiz, Juan José, Escario, José Antonio, da Silva, Patricia Bernardino, Soeiro, Maria de Nazaré C., Gómez-Barrio, Alicia, Arán, Vicente J.
Published in European journal of medicinal chemistry (10.06.2016)
Published in European journal of medicinal chemistry (10.06.2016)
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Journal Article
Synthesis and in vitro and in vivo biological evaluation of substituted nitroquinoxalin-2-ones and 2,3-diones as novel trichomonacidal agents
Ibáñez-Escribano, Alexandra, Reviriego, Felipe, Nogal-Ruiz, Juan José, Meneses-Marcel, Alfredo, Gómez-Barrio, Alicia, Escario, José Antonio, Arán, Vicente J.
Published in European journal of medicinal chemistry (13.04.2015)
Published in European journal of medicinal chemistry (13.04.2015)
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Trichinella: Differing effects of antigens from encapsulated and non-encapsulated species on in vitro nitric oxide production
Andrade, M. Amparo, Siles-Lucas, Mar, López-Abán, Julio, Nogal-Ruiz, Juan José, Pérez-Arellano, José Luis, Martínez-Fernández, Antonio R., Muro, Antonio
Published in Veterinary parasitology (19.01.2007)
Published in Veterinary parasitology (19.01.2007)
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Trichomonacidal Activity of 3,3′-Diindolylmethane (DIM) Is Additive to Metronidazole (MTZ) In Vitro, Supporting Future Oral/Topical Use
Alexandra Ibáñez-Escribano, Leyre Pernaute Lau, Juan José Nogal-Ruiz, Alicia Gómez-Barrio, Jose Antonio Escario, Michael A. Zeligs
Published in Proceedings (01.10.2017)
Published in Proceedings (01.10.2017)
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Immunomodulation of the Response to Excretory/Secretory Antigens of Fasciola hepatica by Anapsos® in Balb/C Mice and Rat Alveolar Macrophages
López-Abán, Julio, Andrade, Maria do Amparo, Nogal-Ruiz, Juan José, Martínez-Fernández, Antonio R, Muro, Antonio
Published in The Journal of parasitology (01.04.2007)
Published in The Journal of parasitology (01.04.2007)
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A computer-based approach to the rational discovery of new trichomonacidal drugs by atom-type linear indices
Marrero-Ponce, Yovani, Machado-Tugores, Yanetsy, Pereira, David Montero, Escario, José Antonio, Barrio, Alicia Gómez, Nogal-Ruiz, Juan José, Ochoa, Carmen, Arán, Vicente J, Martínez-Fernández, Antonio R, Sánchez, Rory N García, Montero-Torres, Alina, Torrens, Francisco, Meneses-Marcel, Alfredo
Published in Current drug discovery technologies (01.12.2005)
Published in Current drug discovery technologies (01.12.2005)
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Journal Article
COMPUESTOS DERIVADOS DE 4-AMINO-N-(4-AMINOFENIL)BENZAMIDA Y ANALOGOS Y USO DE LOS MISMOS
Cisneros Cañas, David, Gómez Barrio, Alicia, Fonseca Berzal, Cristina Rosa, Ibañez Escribano, Alexandra, Escario García-Trevijano, José Antonio, Torrado Durán, Santiago, Dardonville, Christophe, Gamarro Conde, Francisco, Nogal Ruiz, Juan José, Nué Martínez, Jorge Jonathan, Manzano González, José Ignacio
Year of Publication 12.02.2024
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Year of Publication 12.02.2024
Patent
COMPOUNDS DERIVED FROM 4-AMINO-N-(4-AMINOPHENYL)BENZAMIDE AND ANALOGUES AND USE THEREOF
CISNEROS CAÑAS, David, IBAÑEZ ESCRIBANO, Alexandra, NOGAL RUIZ, Juan José, DARDONVILLE, Christophe, TORRADO DURÁN, Santiago, FONSECA BERZAL, Cristina Rosa, ESCARIO GARCÍA-TREVIJANO, José Antonio, NUÉ MARTÍNEZ, Jorge Jonathan, GAMARRO CONDE, Francisco, MANZANO GONZÁLEZ, José Ignacio, GÓMEZ BARRIO, Alicia
Year of Publication 07.09.2023
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Year of Publication 07.09.2023
Patent
AMINES DERIVED FROM 2-BENZYL-5-NITROINDAZOLE WITH ANTIPROTOZOAL PROPERTIES AGAINST TRYPANOSOMA, LEISHMANIA AND TRICHOMONAS
VELA ORTEGA, Nerea, NOGAL RUIZ, Juan José, DARDONVILLE, Christophe, SIFONTES RODRÍGUEZ, Sergio, ESCARIO GARCÍA-TREVIJANO, José Antonio, IBANEZ ESCRIBANO, Alexandra, GOMEZ BARRIO, Alicia, FONSECA BERZAL, Cristina, MENESES MARCEL, Alfredo Irenaldo, ARAN REDO, Vicente
Year of Publication 25.04.2019
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Year of Publication 25.04.2019
Patent