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Published in The New England journal of medicine (29.08.2013)
Published in The New England journal of medicine (29.08.2013)
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Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial
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Published in The Lancet (British edition) (04.01.2014)
Published in The Lancet (British edition) (04.01.2014)
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Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis
Adams, David, Gonzalez-Duarte, Alejandra, O’Riordan, William D, Yang, Chih-Chao, Ueda, Mitsuharu, Kristen, Arnt V, Tournev, Ivailo, Schmidt, Hartmut H, Coelho, Teresa, Berk, John L, Lin, Kon-Ping, Vita, Giuseppe, Attarian, Shahram, Planté-Bordeneuve, Violaine, Mezei, Michelle M, Campistol, Josep M, Buades, Juan, Brannagan, Thomas H, Kim, Byoung J, Oh, Jeeyoung, Parman, Yesim, Sekijima, Yoshiki, Hawkins, Philip N, Solomon, Scott D, Polydefkis, Michael, Dyck, Peter J, Gandhi, Pritesh J, Goyal, Sunita, Chen, Jihong, Strahs, Andrew L, Nochur, Saraswathy V, Sweetser, Marianne T, Garg, Pushkal P, Vaishnaw, Akshay K, Gollob, Jared A, Suhr, Ole B
Published in The New England journal of medicine (05.07.2018)
Published in The New England journal of medicine (05.07.2018)
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Clinical Proof of Concept for a Novel Hepatocyte-Targeting GalNAc-siRNA Conjugate
Zimmermann, Tracy S., Karsten, Verena, Chan, Amy, Chiesa, Joseph, Boyce, Malcolm, Bettencourt, Brian R., Hutabarat, Renta, Nochur, Saraswathy, Vaishnaw, Akshay, Gollob, Jared
Published in Molecular therapy (04.01.2017)
Published in Molecular therapy (04.01.2017)
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First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement
Tabernero, Josep, Shapiro, Geoffrey I, LoRusso, Patricia M, Cervantes, Andres, Schwartz, Gary K, Weiss, Glen J, Paz-Ares, Luis, Cho, Daniel C, Infante, Jeffrey R, Alsina, Maria, Gounder, Mrinal M, Falzone, Rick, Harrop, Jamie, White, Amy C Seila, Toudjarska, Iva, Bumcrot, David, Meyers, Rachel E, Hinkle, Gregory, Svrzikapa, Nenad, Hutabarat, Renta M, Clausen, Valerie A, Cehelsky, Jeffrey, Nochur, Saraswathy V, Gamba-Vitalo, Christina, Vaishnaw, Akshay K, Sah, Dinah W Y, Gollob, Jared A, Burris, 3rd, Howard A
Published in Cancer discovery (01.04.2013)
Published in Cancer discovery (01.04.2013)
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Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis
Butler, James S., Chan, Amy, Costelha, Susete, Fishman, Shannon, Willoughby, Jennifer L. S., Borland, Todd D., Milstein, Stuart, Foster, Donald J., Gonçalves, Paula, Chen, Qingmin, Qin, June, Bettencourt, Brian R., Sah, Dinah W., Alvarez, Rene, Rajeev, Kallanthottathil G., Manoharan, Muthiah, Fitzgerald, Kevin, Meyers, Rachel E., Nochur, Saraswathy V., Saraiva, Maria J., Zimmermann, Tracy S.
Published in Amyloid (01.06.2016)
Published in Amyloid (01.06.2016)
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Phase I First-in-Humans Trial of ALN-TTRsc, a Novel RNA Interference Therapeutic for the Treatment of Familial Amyloidotic Cardiomyopathy (FAC)
Zimmermann, Tracy, Karsten, Verena, Harrop, Jamie, Chan, Amy, Chiesa, Joseph, Peters, Gary, Falzone, Rick, Cehelsky, Jeffrey, Nochur, Saraswathy, Vaishnaw, Akshay, Gollob, Jared
Published in Journal of cardiac failure (01.08.2013)
Published in Journal of cardiac failure (01.08.2013)
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Viral Load Drives Disease in Humans Experimentally Infected with Respiratory Syncytial Virus
DEVINCENZO, John P, WILKINSON, Tom, OXFORD, John, PAREEK, Rajat, MOORE, Ryves, WALSH, Ed, STUDHOLME, Robert, DORSETT, Preston, ALVAREZ, Rene, LAMBKIN-WILLIAMS, Robert, VAISHNAW, Akshay, CEHELSKY, Jeff, MEYERS, Rachel, NOCHUR, Saraswathy, HARRISON, Lisa, MEEKING, Patricia, MANN, Alex, MOANE, Elizabeth
Published in American journal of respiratory and critical care medicine (15.11.2010)
Published in American journal of respiratory and critical care medicine (15.11.2010)
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Assessing unintended hybridization-induced biological effects of oligonucleotides
Lindow, Morten, Vornlocher, Hans-Peter, Riley, Donald, Kornbrust, Douglas J, Burchard, Julja, Whiteley, Laurence O, Kamens, Joanne, Thompson, James D, Nochur, Saraswathy, Younis, Husam, Bartz, Steven, Parry, Joel, Ferrari, Nicolay, Henry, Scott P, Levin, Arthur A
Published in Nature biotechnology (01.10.2012)
Published in Nature biotechnology (01.10.2012)
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METHODS AND COMPOSITIONS FOR PREVENTION OR TREATMENT OF RSV INFECTION
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Year of Publication 25.09.2014
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ELBASHIR, SAYDA, MEYERS, RACHEL, VAISHNAW, AKSHAY, NOCHUR, SARASWATHY, MANOHARAN, MUTHIAH
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Year of Publication 28.09.2012
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Methods And Compositions For Prevention Or Treatment Of RSV Infection
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ELBASHIR, SAYDA, MEYERS, RACHEL, VAISHNAW, AKSHAY, NOCHUR, SARASWATHY, MANOHARAN, MUTHIAH
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Year of Publication 12.01.2011
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