Discovery of Novel 2‑Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors
Iijima, Daisuke, Sugama, Hiroshi, Awai, Nobumasa, Takahashi, Yoichi, Togashi, Yuko, Takebe, Tohru, Xie, Jianshu, Shen, Jingkang, Ke, Ying, Akatsuka, Hidenori, Kawaguchi, Takayuki, Takedomi, Kei, Kashima, Akiko, Nishio, Masashi, Inui, Yosuke, Yoneda, Hikaru, Xia, Guangxin, Iijima, Toru
Published in ACS medicinal chemistry letters (11.08.2022)
Published in ACS medicinal chemistry letters (11.08.2022)
Get full text
Journal Article
COMPOSTOS DE SULFONAMIDA TENDO ATIVIDADE ANTAGONISTA TRPM8
YASUYUKI TSUZUKI, TAKU KATO, TOSHIAKI SAKAMOTO, NOBUMASA AWAI, YASUKI NIWA, DAISUKE SAWAMOTO
Year of Publication 27.09.2022
Get full text
Year of Publication 27.09.2022
Patent
FUSED BICYCLIC COMPOUND
TAKAHASHI, YOICHI, AWAI, NOBUMASA, AKATSUKA, HIDENORI, IIJIMA, TORU, KAWAGUCHI, TAKAYUKI
Year of Publication 07.09.2015
Get full text
Year of Publication 07.09.2015
Patent
FUSED BICYCLIC COMPOUND
TAKAHASHI, YOICHI, AWAI, NOBUMASA, AKATSUKA, HIDENORI, IIJIMA, TORU, KAWAGUCHI, TAKAYUKI
Year of Publication 07.09.2015
Get full text
Year of Publication 07.09.2015
Patent
SULFONAMIDE COMPOUNDS HAVING TRPM8 ANTAGONISTIC ACTIVITY
SAWAMOTO, Daisuke, SAKAMOTO, Toshiaki, NIWA, Yasuki, KATO, Taku, AWAI, Nobumasa, TSUZUKI, Yasuyuki
Year of Publication 28.07.2017
Get full text
Year of Publication 28.07.2017
Patent
compostos de sulfonamida tendo atividade antagonista trpm8
YASUYUKI TSUZUKI, TAKU KATO, TOSHIAKI SAKAMOTO, NOBUMASA AWAI, YASUKI NIWA, DAISUKE SAWAMOTO
Year of Publication 18.07.2017
Get full text
Year of Publication 18.07.2017
Patent
Composto bicíclico fundido
TAKAYUKI KAWAGUCHI, YOICHI TAKAHASHI, NOBUMASA AWAI, HIDENORI AKATSUKA, TORU IJIMA
Year of Publication 17.03.2015
Get full text
Year of Publication 17.03.2015
Patent
SULFONAMIDE COMPOUNDS HAVING TRPM8 ANTAGONISTIC ACTIVITY
KATO TAKU, SAWAMOTO DAISUKE, TSUZUKI YASUYUKI, AWAI NOBUMASA, NIWA YASUKI, SAKAMOTO TOSHIAKI
Year of Publication 31.01.2017
Get full text
Year of Publication 31.01.2017
Patent
Sulfonamide compounds having TRPM8 antagonistic activity
Awai Nobumasa, Sakamoto Toshiaki, Kato Taku, Tsuzuki Yasuyuki, Niwa Yasuki, Sawamoto Daisuke
Year of Publication 10.01.2017
Get full text
Year of Publication 10.01.2017
Patent
SULFONAMIDE COMPOUNDS HAVING TRPM8 ANTAGONISTIC ACTIVITY
YASUYUKI TSUZUKI, TAKU KATO, TOSHIAKI SAKAMOTO, NOBUMASA AWAI, YASUKI NIWA, DAISUKE SAWAMOTO
Year of Publication 02.11.2016
Get full text
Year of Publication 02.11.2016
Patent
Sulfonamidforbindelser med TRPM8-antagonistisk aktivitet
SAWAMOTO, Daisuke, SAKAMOTO, Toshiaki, NIWA, Yasuki, KATO, Taku, AWAI, Nobumasa, TSUZUKI, Yasuyuki
Year of Publication 24.10.2016
Get full text
Year of Publication 24.10.2016
Patent
SULFONAMIDE COMPOUNDS HAVING TRPM8 ANTAGONISTIC ACTIVITY
AWAI, NOBUMASA, TSUZUKI, YASUYUKI, KATO, TAKU, SAWAMOTO, DAISUKE, SAKAMOTO, TOSHIAKI, NIWA, YASUKI
Year of Publication 10.08.2016
Get full text
Year of Publication 10.08.2016
Patent
Compostos de sulfonamida tendo atividade antagonista trpm8
KATO TAKU, SAWAMOTO DAISUKE, TSUZUKI YASUYUKI, AWAI NOBUMASA, NIWA YASUKI, SAKAMOTO TOSHIAKI
Year of Publication 08.09.2021
Get full text
Year of Publication 08.09.2021
Patent
SULFONAMIDE COMPOUNDS HAVING TRPM8 ANTAGONISTIC ACTIVITY
AWAI, NOBUMASA, TSUZUKI, YASUYUKI, KATO, TAKU, SAWAMOTO, DAISUKE, SAKAMOTO, TOSHIAKI, NIWA, YASUKI
Year of Publication 26.07.2016
Get full text
Year of Publication 26.07.2016
Patent
MORPHOLINE DERIVATIVES AS RENIN INHIBITORS
KAWAGUCHI, Takayuki, IIJIMA, Toru, AKATSUKA, Hidenori, SUGAMA, Hiroshi, AWAI, Nobumasa, SHEN, Jingkang, XIA, Guangxin, TAKAHASHI, Yoichi, XIE, Jianshu
Year of Publication 15.02.2017
Get full text
Year of Publication 15.02.2017
Patent
FUSED BICYCLIC COMPOUND
TAKAHASHI, YOICHI, AWAI, NOBUMASA, AKATSUKA, HIDENORI, IIJIMA, TORU, KAWAGUCHI, TAKAYUKI
Year of Publication 26.06.2013
Get full text
Year of Publication 26.06.2013
Patent
Sulfonamide compounds having TRPM8 antagonistic activity
AWAI, NOBUMASA, TSUZUKI, YASUYUKI, KATO, TAKU, SAWAMOTO, DAISUKE, SAKAMOTO, TOSHIAKI, NIWA, YASUKI
Year of Publication 03.09.2015
Get full text
Year of Publication 03.09.2015
Patent
SULFONAMIDE COMPOUNDS HAVING TRPM8 ANTAGONISTIC ACTIVITY
KATO TAKU, SAWAMOTO DAISUKE, TSUZUKI YASUYUKI, AWAI NOBUMASA, NIWA YASUKI, SAKAMOTO TOSHIAKI
Year of Publication 06.08.2015
Get full text
Year of Publication 06.08.2015
Patent
Fused bicyclic compound
KAWAGUCHI TAKAYUKI, AKATSUKA HIDENORI, AWAI NOBUMASA, ILJIMA TORU, TAKAHASHI YOICHI
Year of Publication 02.04.2013
Get full text
Year of Publication 02.04.2013
Patent