Search Results - "NIWA, TOSHIRO" :: K.UTB vyhledávací portál

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Metabolic Activities Catalyzed by Human Cytochrome P450 (CYP) 2D6 and CYP3A Subfamily Members and Effect of Various Compounds, Including Endogenous Steroid Hormones, on These Activities

by Niwa, Toshiro
Published in YAKUGAKU ZASSHI (01.01.2024)

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Regioselective hydroxylation of steroid hormones by human cytochromes P450

by Niwa, Toshiro, Murayama, Norie, Imagawa, Yurie, Yamazaki, Hiroshi
Published in Drug metabolism reviews (01.05.2015)

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Drug interactions between nine antifungal agents and drugs metabolized by human cytochromes P450

by Niwa, Toshiro, Imagawa, Yurie, Yamazaki, Hiroshi
Published in Current drug metabolism (01.01.2014)

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Comparison of the Stimulatory and Inhibitory Effects of Steroid Hormones and α-Naphthoflavone on Steroid Hormone Hydroxylation Catalyzed by Human Cytochrome P450 3A Subfamilies

by Niwa, Toshiro, Toyota, Manami, Kawasaki, Hinako, Ishii, Risa, Sasaki, Shoko
Published in Biological & pharmaceutical bulletin (01.04.2021)

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Role of amino acids at positions 34, 296, and 486 of cytochrome P450 2D6 in the stimulatory and inhibitory effects of psychotropic agents on dopamine formation from p-tyramine

by Niwa, Toshiro, Arima, Juri, Michihiro, Yurina
Published in Xenobiotica (02.11.2021)

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Inhibitory and Stimulatory Effects of Selective Serotonin Reuptake Inhibitors on Cytochrome P450 2D6-mediated Dopamine Formation from p-Tyramine

by Niwa, Toshiro, Sugimoto, Shizuya
Published in Journal of pharmacy & pharmaceutical sciences (2019)

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Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies

by Niwa, Toshiro, Okamoto, Ayaka, Narita, Kanae, Toyota, Manami, Kato, Kyoko, Kobayashi, Kyoko, Sasaki, Shoko
Published in Archives of biochemistry and biophysics (30.03.2020)

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Effect of genetic polymorphism on the inhibition of dopamine formation from p-tyramine catalyzed by brain cytochrome P450 2D6

by Niwa, Toshiro, Shizuku, Marina, Yamano, Kaori
Published in Archives of biochemistry and biophysics (15.04.2017)

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Effect of Antifungal Drugs on Cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 Activities in Human Liver Microsomes

by Niwa, Toshiro, Shiraga, Toshifumi, Takagi, Akira
Published in Biological & Pharmaceutical Bulletin (01.09.2005)

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ヒト薬物代謝酵素シトクロムP450（CYP）2D6及びCYP3Aサブファミリーの代謝反応及び内在性ステロイドホルモンなどによる相互作用

by 丹羽, 俊朗
Published in YAKUGAKU ZASSHI (01.02.2024)

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Effect of Human Cytochrome P450 2D6 Polymorphism on Progesterone Hydroxylation

by Niwa, Toshiro, Sasaki, Shoko, Yamamoto, Yuka, Tanaka, Mayu
Published in European journal of drug metabolism and pharmacokinetics (01.09.2022)

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Substrate Specificity of Human Cytochrome P450 (CYP) 2C Subfamily and Effect of Azole Antifungal Agents on CYP2C8

by Niwa, Toshiro, Imagawa, Yurie
Published in Journal of pharmacy & pharmaceutical sciences (02.11.2016)

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Comparison of Steroid Hormone Hydroxylations by and Docking to Human Cytochromes P450 3A4 and 3A5

by Niwa, Toshiro, Narita, Kanae, Okamoto, Ayaka, Murayama, Norie, Yamazaki, Hiroshi
Published in Journal of pharmacy & pharmaceutical sciences (2019)

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Effect of Cytochrome P450 (CYP) 2D6 Genetic Polymorphism on the Inhibitory Action of Antidepressants on CYP2D6-Mediated Dopamine Formation from p-Tyramine

by Niwa, Toshiro, Yanai, Mayumi, Matsumoto, Maya, Shizuku, Marina
Published in Journal of pharmacy & pharmaceutical sciences (30.03.2018)

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Effect of penicillin-based antibiotics, amoxicillin, ampicillin, and piperacillin, on drug-metabolizing activities of human hepatic cytochromes P450

by Niwa, Toshiro, Morimoto, Mari, Hirai, Takako, Hata, Tomomi, Hayashi, Misato, Imagawa, Yurie
Published in Journal of toxicological sciences (01.02.2016)

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Relative contribution of rat CYP isoforms responsible for stereoselective metabolism of carvedilol

by Iwaki, Masahiro, Niwa, Toshiro, Nakamura, Yukiko, Kawase, Atsushi, Komura, Hiroshi
Published in Journal of toxicological sciences (01.01.2018)

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Comparison of cytochrome P450 2C subfamily members in terms of drug oxidation rates and substrate inhibition

by Niwa, Toshiro, Yamazaki, Hiroshi
Published in Current drug metabolism (01.10.2012)

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Prediction of Hepatic Clearance of Stereoselective Metabolism of Carvedilol in Liver Microsomes and Hepatocytes of Sprague-Dawley and Cytochrome P450 2D-Deficient Dark Agouti Rats

by Iwaki, Masahiro, Niwa, Toshiro, Tanaka, Hiroyuki, Kawase, Atsushi, Komura, Hiroshi
Published in Journal of pharmacy & pharmaceutical sciences (2019)

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Comparison of kinetic parameters for drug oxidation rates and substrate inhibition potential mediated by cytochrome P450 3A4 and 3A5

by Niwa, Toshiro, Murayama, Norie, Emoto, Chie, Yamazaki, Hiroshi
Published in Current drug metabolism (01.01.2008)

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Application of substrate depletion assay to evaluation of CYP isoforms responsible for stereoselective metabolism of carvedilol

by Iwaki, Masahiro, Niwa, Toshiro, Bandoh, Saya, Itoh, Megumi, Hirose, Hitomi, Kawase, Atsushi, Komura, Hiroshi
Published in Drug metabolism and pharmacokinetics (01.12.2016)

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