Cul-Catalyzed Fluorodesulfurization for the Synthesis of Monofluoromethyl Aryl Ethers
Geng, Yang, Liang, Apeng, Gao, Xianying, Niu, Chengshan, Li, Jingya, Zou, Dapeng, Wu, Yusheng, Wu, Yangjie
Published in Journal of organic chemistry (18.08.2017)
Published in Journal of organic chemistry (18.08.2017)
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CuI-Catalyzed Fluorodesulfurization for the Synthesis of Monofluoromethyl Aryl Ethers
Geng, Yang, Liang, Apeng, Gao, Xianying, Niu, Chengshan, Li, Jingya, Zou, Dapeng, Wu, Yusheng, Wu, Yangjie
Published in Journal of organic chemistry (18.08.2017)
Published in Journal of organic chemistry (18.08.2017)
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O-Difluorodeuteromethylation of phenols using difluorocarbene precursors and deuterium oxideElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ob03088f
Geng, Yang, Zhu, Mingxiang, Liang, Apeng, Niu, Chengshan, Li, Jingya, Zou, Dapeng, Wu, Yusheng, Wu, Yangjie
Year of Publication 14.03.2018
Year of Publication 14.03.2018
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Metabolism and pharmacokinetic study of deuterated osimertinib
Zhan, Xuyi, Bao, Shaoyin, Li, Xumei, Zhou, Shaojun, Dahar, Maha Raja, Lin, Nengming, Chen, Xiugui, Niu, Chengshan, Ji, Kaige, Wu, Yusheng, Zeng, Kui, Tang, Zhihua, Yu, Lushan
Published in Biopharmaceutics & drug disposition (01.04.2023)
Published in Biopharmaceutics & drug disposition (01.04.2023)
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EGFR 단백질 분해용 화합물 및 이의 용도
HAN SHUNXUN, LI JUN, LIANG APENG, CHEN SHAOQING, WU YUSHENG, DONG SHENGLI, NIU CHENGSHAN
Year of Publication 10.07.2024
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Year of Publication 10.07.2024
Patent
CDK 키나아제 억제제로 사용되는 화합물 및 이의 용도
LI MEIHUA, LI JUN, CHEN MINGTAO, LIANG APENG, WU YUSHENG, DONG SHENGLI, NIU CHENGSHAN
Year of Publication 16.02.2024
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Year of Publication 16.02.2024
Patent
Abstract 3400: TY-2136b, a next generation ROS1/TRK/ALK inhibitor, potently inhibits kinase and cell proliferation activities of tumor cells bearing drug-dependent acquired mutations
Niu, Chengshan, Liang, Apeng, Dou, Yuge, Ji, Kaige, Li, Meihua, Zhao, Yanchao, Zhang, Yan, Guo, Zhongwei, Gong, Aishen, Jiang, Mingyu, Chen, Shaoqing, Chen, Xiugui, Li, Jun, Wu, Yusheng
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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CDK7 키나아제 억제제로서의 화합물 및 이의 용도
LI MEIHUA, LI JUN, LIANG APENG, WU YUSHENG, DONG SHENGLI, NIU CHENGSHAN
Year of Publication 31.03.2023
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Year of Publication 31.03.2023
Patent
Abstract 3419: TY-1091, a highly selective and potent second-generation RET inhibitor, demonstrates superior antitumor activity in multiple RET-mutant models
Niu, Chengshan, Zheng, Maolin, Wang, Huan, Ji, Kaige, Li, Meihua, Wang, Guohui, Ni, Rongzhen, Liang, Apeng, Gong, Aishen, Zhang, Yazhen, Su, Hui, Jiang, Mingyu, Chen, Shaoqing, Chen, Xiugui, Li, Jun, Wu, Yusheng
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 4488: TY-4028: a novel, targeted therapy for non small-cell lung cancer with EGFR exon 20 or HER2 exon 20 insertion mutations
Li, Jun, Niu, Chengshan, Guo, Zhongwei, Wang, Huan, Zheng, Bailu, Dou, Yuge, Liang, Apeng, Ji, Kaige, Dong, Shengli, Li, Meihua, Zhao, Yanchao, Zhang, Yazhen, Gong, Aishen, Liu, Hao, Hu, Xinmiao, Su, Hui, Jiang, Mingyu, Chen, Shaoqing, Chen, Xiugui, Wu, Yusheng
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 4491: TY-0584: A potent, orally available small molecule YAP/TEAD inhibitor, exhibits anti-tumor effects in vitro and in vivo
Liang, Apeng, Dong, Shengli, Liu, Guangbin, Guo, Zhengfei, Li, Meihua, Han, Shuaibo, Cao, Yundi, Tu, Yian, Zhou, Chao, Yu, Yu, Xiao, Linglin, Huang, Wei, Yang, Xinlong, Fang, Lian, Li, Haoyun, Niu, Chengshan, Jiang, Mingyu, Xing, Feng, Chen, Shaoqing, Li, Jun, Wu, Yusheng
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 5979: TY-0540, a highly potent CDK2/4/6 inhibitor, attenuates acquired resistance against CDK4/6 inhibition
Li, Meihua, Niu, Chengshan, Chen, Mingtao, Ji, Kaige, Xu, Hui, Dong, Shengli, Zhang, Yan, Meng, Qinguo, Dou, Yuge, Wang, Yijun, Wu, Rui, Tu, Yian, Zhou, Chao, Liang, Apeng, Wang, Huan, Ni, Rongzhen, Gong, Aishen, Su, Hui, Jiang, Mingyu, Xing, Feng, Chen, Shaoqing, Chen, Xiugui, Li, Jun, Wu, Yusheng
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 5981: TY-2699a is a highly potent CDK7 inhibitor to abolish dysfunctional tumor cell cycle for clinical development
Dong, Shengli, Liang, Apeng, Zhu, Jian, Wang, Huan, Li, Meihua, Wang, Kai, Ni, Rongzhen, Li, Haoyun, Cao, Yundi, Xiao, Linglin, Li, Hongqiang, Tu, Yian, Zhou, Chao, Gong, Aishen, Xu, Shuyi, Su, Hui, Niu, Chengshan, Jiang, Mingyu, Xing, Feng, Chen, Xiugui, Chen, Shaoqing, Li, Jun, Wu, Yusheng
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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