PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis
Sandborn, William J., Mattheakis, Larry C., Modi, Nishit B., Pugatch, David, Bressler, Brian, Lee, Scott, Bhandari, Raj, Kanwar, Bittoo, Shames, Richard, D’Haens, Geert, Schreiber, Stefan, Danese, Silvio, Feagan, Brian, Pai, Rish K., Liu, David Y., Gupta, Suneel
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2021)
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JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans
Fourie, Anne M., Cheng, Xiaoli, Chang, Leon, Greving, Carrie, Li, Xinyi, Knight, Beverly, Polidori, David, Patrick, Aaron, Bains, Trpta, Steele, Ruth, Allen, Samantha J., Patch, Raymond J., Sun, Chengzao, Somani, Sandeep, Bhandari, Ashok, Liu, David, Huie, Keith, Li, Shu, Rodriguez, Michael A., Xue, Xiaohua, Kannan, Arun, Kosoglou, Teddy, Sherlock, Jonathan P., Towne, Jennifer, Holland, M. Claire, Modi, Nishit B.
Published in Scientific reports (30.07.2024)
Published in Scientific reports (30.07.2024)
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Journal Article
Crossover comparison of IPX066 and a standard levodopa formulation in advanced Parkinson's disease
Hauser, Robert A., Ellenbogen, Aaron L., Metman, Leo Verhagen, Hsu, Ann, O'Connell, Martin J., Modi, Nishit B., Yao, Hsuan-Ming, Kell, Sherron H., Gupta, Suneel K.
Published in Movement disorders (01.10.2011)
Published in Movement disorders (01.10.2011)
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Pharmacokinetics, pharmacodynamics, and tolerability of an aqueous formulation of rusfertide (PTG‐300), a hepcidin mimetic, in healthy volunteers: A double‐blind first‐in‐human study
Modi, Nishit B., Shames, Richard, Lickliter, Jason D., Gupta, Suneel
Published in European journal of haematology (01.09.2024)
Published in European journal of haematology (01.09.2024)
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Comparison of the pharmacokinetics of an oral extended-release capsule formulation of carbidopa-levodopa (IPX066) with immediate-release carbidopa-levodopa (Sinemet(®)), sustained-release carbidopa-levodopa (Sinemet(®) CR), and carbidopa-levodopa-entacapone (Stalevo(®))
Hsu, Ann, Yao, Hsuan-Ming, Gupta, Suneel, Modi, Nishit B
Published in Journal of clinical pharmacology (01.09.2015)
Published in Journal of clinical pharmacology (01.09.2015)
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Journal Article
Comparison of the pharmacokinetics of an oral extended‐release capsule formulation of carbidopa‐levodopa (IPX066) with immediate‐release carbidopa‐levodopa (Sinemet®), sustained‐release carbidopa‐levodopa (Sinemet® CR), and carbidopa‐levodopa‐entacapone (Stalevo®)
Hsu, Ann, Yao, Hsuan‐Ming, Gupta, Suneel, Modi, Nishit B.
Published in Journal of clinical pharmacology (01.09.2015)
Published in Journal of clinical pharmacology (01.09.2015)
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Journal Article
Rusfertide, a Hepcidin Mimetic, for Control of Erythrocytosis in Polycythemia Vera
Kremyanskaya, Marina, Kuykendall, Andrew T., Pemmaraju, Naveen, Ritchie, Ellen K., Gotlib, Jason, Gerds, Aaron, Palmer, Jeanne, Pettit, Kristen, Nath, Uttam K., Yacoub, Abdulraheem, Molina, Arturo, Saks, Samuel R., Modi, Nishit B., Valone, Frank H., Khanna, Sarita, Gupta, Suneel, Verstovsek, Srdan, Ginzburg, Yelena Z., Hoffman, Ronald
Published in The New England journal of medicine (22.02.2024)
Published in The New England journal of medicine (22.02.2024)
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Journal Article
Rusfertide for iron overload in haemochromatosis - Authors' reply
Kowdley, Kris V, Modi, Nishit B, Valone, Frank H
Published in The lancet. Gastroenterology & hepatology (01.03.2024)
Published in The lancet. Gastroenterology & hepatology (01.03.2024)
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Pharmacokinetics, metabolism, and excretion of nefopam, a dual reuptake inhibitor in healthy male volunteers
Sanga, Madhu, Banach, John, Ledvina, Aaron, Modi, Nishit B., Mittur, Aravind
Published in Xenobiotica (01.11.2016)
Published in Xenobiotica (01.11.2016)
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Journal Article
Single-Dose Pharmacokinetics and Pharmacodynamics of IPX203 in Patients With Advanced Parkinson Disease: A Comparison With Immediate-Release Carbidopa-Levodopa and With Extended-Release Carbidopa-Levodopa Capsules
Modi, Nishit B, Mittur, Aravind, Rubens, Robert, Khanna, Sarita, Gupta, Suneel
Published in Clinical neuropharmacology (01.01.2019)
Published in Clinical neuropharmacology (01.01.2019)
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Journal Article
Rusfertide for the treatment of iron overload in HFE-related haemochromatosis: an open-label, multicentre, proof-of-concept phase 2 trial
Kowdley, Kris V, Modi, Nishit B, Peltekian, Kevork, Vierling, John M, Ferris, Christopher, Valone, Frank H, Gupta, Suneel
Published in The lancet. Gastroenterology & hepatology (01.12.2023)
Published in The lancet. Gastroenterology & hepatology (01.12.2023)
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Single‐ and Multiple‐Dose Pharmacokinetics and Pharmacodynamics of PN‐943, a Gastrointestinal‐Restricted Oral Peptide Antagonist of α4β7, in Healthy Volunteers
Modi, Nishit B., Cheng, Xiaoli, Mattheakis, Larry, Hwang, Ching‐Chang, Nawabi, Roya, Liu, David, Gupta, Suneel
Published in Clinical pharmacology in drug development (01.11.2021)
Published in Clinical pharmacology in drug development (01.11.2021)
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Journal Article
Pharmacokinetics, distribution, metabolism, and excretion of the dual reuptake inhibitor [14C]-nefopam in rats
Yu, Jian, Solon, Eric, Shen, Helen, Modi, Nishit B., Mittur, Aravind
Published in Xenobiotica (01.11.2016)
Published in Xenobiotica (01.11.2016)
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Journal Article
Population Pharmacodynamics of IPX066: An Oral Extended‐Release Capsule Formulation of Carbidopa–Levodopa, and Immediate‐Release Carbidopa–Levodopa in Patients With Advanced Parkinson's Disease
Mao, Zhongping, Hsu, Ann, Gupta, Suneel, Modi, Nishit B.
Published in Journal of clinical pharmacology (01.05.2013)
Published in Journal of clinical pharmacology (01.05.2013)
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