Identification of an orally active small-molecule PTHR1 agonist for the treatment of hypoparathyroidism
Tamura, Tatsuya, Noda, Hiroshi, Joyashiki, Eri, Hoshino, Maiko, Watanabe, Tomoyuki, Kinosaki, Masahiko, Nishimura, Yoshikazu, Esaki, Tohru, Ogawa, Kotaro, Miyake, Taiji, Arai, Shinichi, Shimizu, Masaru, Kitamura, Hidetomo, Sato, Haruhiko, Kawabe, Yoshiki
Published in Nature communications (18.11.2016)
Published in Nature communications (18.11.2016)
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Journal Article
Radioprotection of mice by lactoferrin against irradiation with sublethal X-rays
Nishimura, Yoshikazu, Homma-Takeda, Shino, Kim, Hee-Sun, Kakuta, Izuru
Published in Journal of radiation research (01.03.2014)
Published in Journal of radiation research (01.03.2014)
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Journal Article
Estimation of hydroxyl radical generation by salicylate hydroxylation method in kidney of mice exposed to ferric nitrilotriacetate and potassium bromate
Ueno, Shunji, Kashimoto, Takashige, Susa, Nobuyuki, Shiho, Kensuke, Seki, Takashi, Ito, Nobuhiko, Takeda-Homma, Shino, Nishimura, Yoshikazu, Sugiyama, Masayasu
Published in Free radical research (01.11.2007)
Published in Free radical research (01.11.2007)
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Journal Article
Estimation of hydroxyl radical generation by salicylate hydroxylation method in multiple organs of mice exposed to whole-body X-ray irradiation
Ueno, Shunji, Kashimoto, Takashige, Susa, Nobuyuki, Wada, Kohshin, Ito, Nobuhiko, Takeda-Homma, Shino, Nishimura, Yoshikazu, Sugiyama, Masayasu
Published in Free radical research (01.09.2006)
Published in Free radical research (01.09.2006)
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Journal Article
Unsupervised Speaker Adaptation for DNN-based Speech Synthesis using Input Codes
Takaki, Shinji, Nishimura, Yoshikazu, Yamagishi, Junichi
Published in 2018 Asia-Pacific Signal and Information Processing Association Annual Summit and Conference (APSIPA ASC) (01.11.2018)
Published in 2018 Asia-Pacific Signal and Information Processing Association Annual Summit and Conference (APSIPA ASC) (01.11.2018)
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Conference Proceeding
Radioprotective Effect of Chitosan in Sub-lethally X-ray Irradiated Mice
Nishimura, Yoshikazu, Kim, Hee-Sun, Ikota, Nobuo, Arima, Hiromi, Bom, Hee-Seung, Kim, Young-Ho, Watanabe, Yoshito, Yukawa, Masae, Ozawa, Toshihiko
Published in JOURNAL OF RADIATION RESEARCH (01.03.2003)
Published in JOURNAL OF RADIATION RESEARCH (01.03.2003)
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Journal Article
Synthesis and Biological Evaluations of Novel Human Parathyroid Hormone 1 Receptor (hPTHR1) Agonists Bearing Bicyclic Aromatic Moiety
Nishimura, Yoshikazu, Esaki, Toru, Isshiki, Yoshiaki, Furuta, Yoshiyuki, Emura, Takashi, Watanabe, Yoshiaki, Ohta, Masateru, Arai, Shinichi, Noda, Hiroshi, Shimizu, Masaru, Tamura, Tatsuya, Sato, Haruhiko
Published in ChemMedChem (01.03.2024)
Published in ChemMedChem (01.03.2024)
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Journal Article
Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets
Ohta, Atsushi, Tanada, Mikimasa, Shinohara, Shojiro, Morita, Yuya, Nakano, Kazuhiko, Yamagishi, Yusuke, Takano, Ryusuke, Kariyuki, Shiori, Iida, Takeo, Matsuo, Atsushi, Ozeki, Kazuhisa, Emura, Takashi, Sakurai, Yuuji, Takano, Koji, Higashida, Atsuko, Kojima, Miki, Muraoka, Terushige, Takeyama, Ryuuichi, Kato, Tatsuya, Kimura, Kaori, Ogawa, Kotaro, Ohara, Kazuhiro, Tanaka, Shota, Kikuchi, Yasufumi, Hisada, Nozomi, Hayashi, Ryuji, Nishimura, Yoshikazu, Nomura, Kenichi, Tachibana, Tatsuhiko, Irie, Machiko, Kawada, Hatsuo, Torizawa, Takuya, Murao, Naoaki, Kotake, Tomoya, Tanaka, Masahiko, Ishikawa, Shiho, Miyake, Taiji, Tamiya, Minoru, Arai, Masako, Chiyoda, Aya, Akai, Sho, Sase, Hitoshi, Kuramoto, Shino, Ito, Toshiya, Shiraishi, Takuya, Kojima, Tetsuo, Iikura, Hitoshi
Published in Journal of the American Chemical Society (08.11.2023)
Published in Journal of the American Chemical Society (08.11.2023)
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Journal Article
Lead Optimization and Avoidance of Reactive Metabolite Leading to PCO371, a Potent, Selective, and Orally Available Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist
Nishimura, Yoshikazu, Esaki, Toru, Isshiki, Yoshiaki, Furuta, Yoshiyuki, Mizutani, Akemi, Kotake, Tomoya, Emura, Takashi, Watanabe, Yoshiaki, Ohta, Masateru, Nakagawa, Toshito, Ogawa, Kotaro, Arai, Shinichi, Noda, Hiroshi, Kitamura, Hidetomo, Shimizu, Masaru, Tamura, Tatsuya, Sato, Haruhiko
Published in Journal of medicinal chemistry (28.05.2020)
Published in Journal of medicinal chemistry (28.05.2020)
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Journal Article
Structure-activity relationships of middle-size cyclic peptides, KRAS inhibitors derived from an mRNA display
Kage, Mirai, Hayashi, Ryuji, Matsuo, Atsushi, Tamiya, Minoru, Kuramoto, Shino, Ohara, Kazuhiro, Irie, Machiko, Chiyoda, Aya, Takano, Koji, Ito, Toshiya, Kotake, Tomoya, Takeyama, Ryuuichi, Ishikawa, Shiho, Nomura, Kenichi, Furuichi, Noriyuki, Morita, Yuya, Hashimoto, Satoshi, Kawada, Hatsuo, Nishimura, Yoshikazu, Nii, Keiji, Sase, Hitoshi, Ohta, Atsushi, Kojima, Tetsuo, Iikura, Hitoshi, Tanada, Mikimasa, Shiraishi, Takuya
Published in Bioorganic & medicinal chemistry (01.08.2024)
Published in Bioorganic & medicinal chemistry (01.08.2024)
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Journal Article
Anesthetic case report of a patient with chronic inflammatory demyelinating polyneuropathy
Kashiwagi, Rieko, Nishimura, Yoshikazu, Nishikawa, Haruko, Satoh, Minako, Fujimoto, Keiko, Okazaki, Kaoru
Published in Masui. The Japanese journal of anesthesiology (01.04.2009)
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Published in Masui. The Japanese journal of anesthesiology (01.04.2009)
Journal Article
Development of a Novel Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist (CH5447240), a Potent and Orally Available Small Molecule for Treatment of Hypoparathyroidism
Nishimura, Yoshikazu, Esaki, Toru, Isshiki, Yoshiaki, Okamoto, Naoki, Furuta, Yoshiyuki, Kotake, Tomoya, Watanabe, Yoshiaki, Ohta, Masateru, Nakagawa, Toshito, Noda, Hiroshi, Shimizu, Masaru, Saito, Hitoshi, Tamura, Tatsuya, Sato, Haruhiko
Published in Journal of medicinal chemistry (26.07.2018)
Published in Journal of medicinal chemistry (26.07.2018)
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Journal Article