506 Samelisant: Baseline Characteristics from a Phase 2 Study Evaluating Efficacy and Safety in Patients with Narcolepsy
Nirogi, Ramakrishna, Ravula, Jyothsna, Jayarajan, Pradeep, Jetta, Satish, Bhyrapuneni, Gopinadh, Benade, Vijay, Shinde, Anil, Goyal, Vinod
Published in Sleep (New York, N.Y.) (03.05.2021)
Published in Sleep (New York, N.Y.) (03.05.2021)
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Journal Article
0054 SUVN-G3031, a Histamine H3 Receptor Inverse Agonist Produces Wake Promoting Effect in Orexin-2-saporin Lesioned Rats
Benade, Vijay, Daripelli, Saivishal, Tirumalasetty, Chaitanya, Subramanian, Ramkumar, Petlu, Surendra, Badange, Rajesh, Nirogi, Ramakrishna
Published in Sleep (New York, N.Y.) (13.04.2019)
Published in Sleep (New York, N.Y.) (13.04.2019)
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Journal Article
005 Samelisant (SUVN-G3031), a histamine H3 receptor inverse agonist in animal models of sleep disorders
Daripelli, Saivishal, Molgara, Parusharamulu, Muddana, Nageswararao, Jayarajan, Pradeep, Mekala, Venkat Reddy, Reballi, Veena, Achanta, Pramod Kumar, Nirogi, Ramakrishna
Published in Sleep (New York, N.Y.) (03.05.2021)
Published in Sleep (New York, N.Y.) (03.05.2021)
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Journal Article
004 Samelisant (SUVN-G3031), Differentiating features over current treatments of narcolepsy
Shinde, Anil, Subramanian, Ramkumar, Palacharla, Raghava, Benade, Vijay, Abraham, Renny, Kamuju, Venkatesh, Pandey, Santosh, Badange, Rajesh, Achanta, Pramod Kumar, Nirogi, Ramakrishna
Published in Sleep (New York, N.Y.) (03.05.2021)
Published in Sleep (New York, N.Y.) (03.05.2021)
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Journal Article
Potential beneficial effects of masupirdine (SUVN‐502) on agitation/aggression and psychosis in patients with moderate Alzheimer's disease: Exploratory post hoc analyses
Nirogi, Ramakrishna, Jayarajan, Pradeep, Benade, Vijay, Shinde, Anil, Goyal, Vinod Kumar, Jetta, Satish, Ravula, Jyothsna, Abraham, Renny, Grandhi, Venkata Ramalingayya, Subramanian, Ramkumar, Pandey, Santosh Kumar, Badange, Rajesh Kumar, Mohammed, Abdul Rasheed, Jasti, Venkat, Ballard, Clive, Cummings, Jeffrey
Published in International journal of geriatric psychiatry (01.10.2022)
Published in International journal of geriatric psychiatry (01.10.2022)
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Journal Article
0139 SUVN-G3031, A Potent and Selective Histamine H3 Receptor Inverse Agonist - Phase-2 Investigational New Drug for the Treatment of Narcolepsy - Differentiating Factors with Competitor Clinical Candidates
Nirogi, Ramakrishna, Bhyrapuneni, Gopinadh, Abraham, Renny, Subramanian, Ramkumar, Goyal, Vinod Kumar, Pandey, Santosh Kumar, Badange, Rajesh, Shinde, Anil
Published in Sleep (New York, N.Y.) (13.04.2019)
Published in Sleep (New York, N.Y.) (13.04.2019)
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Journal Article
Samelisant (SUVN-G3031), a potent, selective and orally active histamine H3 receptor inverse agonist for the potential treatment of narcolepsy: pharmacological and neurochemical characterisation
Nirogi, Ramakrishna, Benade, Vijay, Daripelli, Saivishal, Subramanian, Ramkumar, Kamuju, Venkatesh, Bhyrapuneni, Gopinadh, Muddana, Nageswara Rao, Mekala, Venkat Reddy, Petlu, Surendra, Jayarajan, Pradeep, Badange, Rajesh, Shinde, Anil, Jasti, Venkat
Published in Psychopharmacology (01.06.2021)
Published in Psychopharmacology (01.06.2021)
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Journal Article
Design, synthesis and pharmacological evaluation of 4-(piperazin-1-yl methyl)-N1-arylsulfonyl indole derivatives as 5-HT6 receptor ligands
Nirogi, Ramakrishna V.S., Badange, Rajeshkumar, Kambhampati, Ramasastri, Chindhe, Anil, Deshpande, Amol D., Tiriveedhi, Vinaykumar, Kandikere, Vishwottam, Muddana, Nageswararao, Abraham, Renny, Khagga, Mukkanti
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
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Journal Article
N,N-Dimethyl-[9-(arylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl]amines as novel, potent and selective 5-HT6 receptor antagonists
Nirogi, Ramakrishna V.S., Konda, Jagadishu Babu, Kambhampati, Ramasastry, Shinde, Anil, Bandyala, Thrinath Reddy, Gudla, Parandhama, Kandukuri, Kiran Kumar, Jayarajan, Pradeep, Kandikere, Vishwottam, Dubey, P.K.
Published in Bioorganic & medicinal chemistry letters (15.11.2012)
Published in Bioorganic & medicinal chemistry letters (15.11.2012)
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Journal Article
0120 SUVN-G3031, a Novel, Potent and Selective Histamine H3 Receptor Inverse Agonist for the Treatment of Narcolepsy: Preclinical Characterization
Bhayrapuneni, Gopinadh, Kamuju, Venkatesh, Gandipudi, Sudhakar, Jayarajan, Pradeep, Abraham, Renny, Bojja, Kumar, Pandey, Santosh Kumar, Mekala, Venkat Reddy, Nirogi, Ramakrishna
Published in Sleep (New York, N.Y.) (13.04.2019)
Published in Sleep (New York, N.Y.) (13.04.2019)
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Journal Article
Progress in Investigational Agents Targeting Serotonin-6 Receptors for the Treatment of Brain Disorders
Nirogi, Ramakrishna, Jayarajan, Pradeep, Shinde, Anil, Mohammed, Abdul Rasheed, Grandhi, Venkata Ramalingayya, Benade, Vijay, Goyal, Vinod Kumar, Abraham, Renny, Jasti, Venkat, Cummings, Jeffrey
Published in Biomolecules (Basel, Switzerland) (07.02.2023)
Published in Biomolecules (Basel, Switzerland) (07.02.2023)
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Journal Article
Histamine 3 receptor inverse agonist Samelisant (SUVN-G3031): Pharmacological characterization of an investigational agent for the treatment of cognitive disorders
Nirogi, Ramakrishna, Grandhi, Venkata R, Medapati, Rajesh B, Ganuga, Narender, Benade, Vijay, Gandipudi, Sudhakar, Manoharan, Arunkumar, Abraham, Renny, Jayarajan, Pradeep, Bhyrapuneni, Gopinadh, Shinde, Anil, Badange, Rajesh K, Subramanian, Ramkumar, Petlu, Surendra, Jasti, Venkat
Published in Journal of psychopharmacology (Oxford) (01.06.2021)
Published in Journal of psychopharmacology (Oxford) (01.06.2021)
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Journal Article
Synthesis and biological evaluation of novel N1-phenylsulphonyl indole derivatives as potent and selective 5-HT6R ligands for the treatment of cognitive disorders
Nirogi, Ramakrishna V. S., Bandyala, Thrinath Reddy, Gangadasari, Pamuletinarasimha Reddy, Khagga, Mukkanti
Published in Journal of enzyme inhibition and medicinal chemistry (01.11.2016)
Published in Journal of enzyme inhibition and medicinal chemistry (01.11.2016)
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Journal Article
0053 SUVN-G3031: Safety, Tolerability and Pharmacokinetics of a Potent and Selective Histamine H3 Receptor Inverse Agonist - Single and Multiple Ascending Doses in Healthy Subjects
Nirogi, Ramakrishna, Shinde, Anil, Mudigonda, Koteshwara, Bhyrapuneni, Gopinadh, Muddana, Nageswara Rao, Palacharla, Raghava Chowdary, Ajjala, Devender Reddy, Goyal, Vinod Kumar, Ravula, Jyothsna, Jetta, Satish, Mohammed, Abdul Rasheed
Published in Sleep (New York, N.Y.) (13.04.2019)
Published in Sleep (New York, N.Y.) (13.04.2019)
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Journal Article
1‐[2‐(1‐Cyclobutylpiperidin‐4‐yloxy)‐6,7‐dihydro‐4H‐thiazolo[5,4‐c]pyridin‐5‐yl]propan‐1‐one: a Histamine H3 Receptor Inverse Agonist with Efficacy in Animal Models of Cognition
Shinde, Anil Karbhari, Badange, Rajesh Kumar, Reballi, Veena, Achanta, Pramod Kumar, Bojja, Kumar, Manchineella, Sravanthi, Rao Muddana, Nageswara, Subramanian, Ramkumar, Choudary Palacharla, Raghava, Benade, Vijay, Jayarajan, Pradeep, Thentu, Jagadeesh Babu, Lingavarapu, Bujji Babu, Yarra, Sivasekhar, Kagita, Narendra, Rao Doguparthi, Mallikarjuna, Mohammed, Abdul Rasheed, Nirogi, Ramakrishna
Published in ChemMedChem (04.02.2022)
Published in ChemMedChem (04.02.2022)
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Journal Article
Comparison of manual and automated filaments for evaluation of neuropathic pain behavior in rats
Nirogi, Ramakrishna, Goura, Venkatesh, Shanmuganathan, Dhanalakshmi, Jayarajan, Pradeep, Abraham, Renny
Published in Journal of pharmacological and toxicological methods (01.07.2012)
Published in Journal of pharmacological and toxicological methods (01.07.2012)
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Journal Article
Development, validation, and application of an ultra-high performance liquid chromatography-tandem mass spectrometry method for the estimation of Ropanicant in human plasma and urine
Nirogi, Ramakrishna, Kalaikadhiban, Ilayaraja, Rayapati, Lakshmi Prasanna, Pantangi, Hanumanth Rao, Chunduru, Prathyusha, Jetta, Satish, Jubre, Avinash, Mohammed, Abdul Rasheed
Published in Journal of Chromatography Open (01.11.2023)
Published in Journal of Chromatography Open (01.11.2023)
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Journal Article
Inhibition of cytochrome P450 enzymes by saturated and unsaturated fatty acids in human liver microsomes, characterization of enzyme kinetics in the presence of bovine serum albumin (0.1 and 1.0% w/v) and in vitro – in vivo extrapolation of hepatic clearance
Palacharla, Raghava Choudary, Uthukam, Venkatesham, Manoharan, Arunkumar, Ponnamaneni, Ranjith Kumar, Padala, Nagasurya Prakash, Boggavarapu, Rajesh Kumar, Bhyrapuneni, Gopinadh, Ajjala, Devender Reddy, Nirogi, Ramakrishna
Published in European journal of pharmaceutical sciences (01.04.2017)
Published in European journal of pharmaceutical sciences (01.04.2017)
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Journal Article
Synthesis and biological evaluation of novel N 1 -phenylsulphonyl indole derivatives as potent and selective 5-HT 6 R ligands for the treatment of cognitive disorders
Nirogi, Ramakrishna V S, Bandyala, Thrinath Reddy, Gangadasari, Pamuletinarasimha Reddy, Khagga, Mukkanti
Published in Journal of enzyme inhibition and medicinal chemistry (01.11.2016)
Published in Journal of enzyme inhibition and medicinal chemistry (01.11.2016)
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Journal Article