APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication
Seplyarskiy, Vladimir B, Soldatov, Ruslan A, Popadin, Konstantin Y, Antonarakis, Stylianos E, Bazykin, Georgii A, Nikolaev, Sergey I
Published in Genome research (01.02.2016)
Published in Genome research (01.02.2016)
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Responsiveness to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade in SB28 and GL261 mouse glioma models
Genoud, Vassilis, Marinari, Eliana, Nikolaev, Sergey I, Castle, John C, Bukur, Valesca, Dietrich, Pierre-Yves, Okada, Hideho, Walker, Paul R
Published in Oncoimmunology (02.12.2018)
Published in Oncoimmunology (02.12.2018)
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Genomic mutation landscape of skin cancers from DNA repair-deficient xeroderma pigmentosum patients
Yurchenko, Andrey A., Rajabi, Fatemeh, Braz-Petta, Tirzah, Fassihi, Hiva, Lehmann, Alan, Nishigori, Chikako, Wang, Jinxin, Padioleau, Ismael, Gunbin, Konstantin, Panunzi, Leonardo, Morice-Picard, Fanny, Laplante, Pierre, Robert, Caroline, Kannouche, Patricia L., Menck, Carlos F. M., Sarasin, Alain, Nikolaev, Sergey I.
Published in Nature communications (04.05.2023)
Published in Nature communications (04.05.2023)
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Journal Article
Phylogenomics reshuffles the eukaryotic supergroups
Burki, Fabien, Shalchian-Tabrizi, Kamran, Minge, Marianne, Skjaeveland, Asmund, Nikolaev, Sergey I, Jakobsen, Kjetill S, Pawlowski, Jan
Published in PloS one (29.08.2007)
Published in PloS one (29.08.2007)
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Journal Article
Deciphering resistance mechanisms in cancer: final report of MATCH-R study with a focus on molecular drivers and PDX development
Vasseur, Damien, Bigot, Ludovic, Beshiri, Kristi, Flórez-Arango, Juan, Facchinetti, Francesco, Hollebecque, Antoine, Tselikas, Lambros, Aldea, Mihaela, Blanc-Durand, Felix, Gazzah, Anas, Planchard, David, Lacroix, Ludovic, Pata-Merci, Noémie, Nobre, Catline, Da Silva, Alice, Nicotra, Claudio, Ngo-Camus, Maud, Braye, Floriane, Nikolaev, Sergey I, Michiels, Stefan, Jules-Clement, Gérôme, Olaussen, Ken André, André, Fabrice, Scoazec, Jean-Yves, Barlesi, Fabrice, Ponce, Santiago, Soria, Jean-Charles, Besse, Benjamin, Loriot, Yohann, Friboulet, Luc
Published in Molecular cancer (04.10.2024)
Published in Molecular cancer (04.10.2024)
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Gene Age Predicts the Strength of Purifying Selection Acting on Gene Expression Variation in Humans
Popadin, Konstantin Y., Gutierrez-Arcelus, Maria, Lappalainen, Tuuli, Buil, Alfonso, Steinberg, Julia, Nikolaev, Sergey I., Lukowski, Samuel W., Bazykin, Georgii A., Seplyarskiy, Vladimir B., Ioannidis, Panagiotis, Zdobnov, Evgeny M., Dermitzakis, Emmanouil T., Antonarakis, Stylianos E.
Published in American journal of human genetics (04.12.2014)
Published in American journal of human genetics (04.12.2014)
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Journal Article
Early-onset gynecological tumors in DNA repair-deficient xeroderma pigmentosum group C patients: a case series
Yurchenko, Andrey. A., Fresneau, Brice, Borghese, Bruno, Rajabi, Fatemeh, Tata, Zora, Genestie, Catherine, Sarasin, Alain, Nikolaev, Sergey I.
Published in Communications medicine (11.08.2023)
Published in Communications medicine (11.08.2023)
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Journal Article
The Twilight of Heliozoa and Rise of Rhizaria, an Emerging Supergroup of Amoeboid Eukaryotes
Nikolaev, Sergey I., Berney, Cédric, Fahrni, José F., Bolivar, Ignacio, Polet, Stephane, Mylnikov, Alexander P., Aleshin, Vladimir V., Petrov, Nikolai B., Pawlowski, Jan, Doolittle, W. Ford
Published in Proceedings of the National Academy of Sciences - PNAS (25.05.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (25.05.2004)
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Journal Article
Life-history traits drive the evolutionary rates of mammalian coding and noncoding genomic elements
Nikolaev, Sergey I, Montoya-Burgos, Juan I, Popadin, Konstantin, Parand, Leila, Margulies, Elliott H, Antonarakis, Stylianos E
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2007)
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Journal Article
Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain
Nikolaev, Sergey I, Vetiska, Sandra, Bonilla, Ximena, Boudreau, Emilie, Jauhiainen, Suvi, Rezai Jahromi, Behnam, Khyzha, Nadiya, DiStefano, Peter V, Suutarinen, Santeri, Kiehl, Tim-Rasmus, Mendes Pereira, Vitor, Herman, Alexander M, Krings, Timo, Andrade-Barazarte, Hugo, Tung, Takyee, Valiante, Taufik, Zadeh, Gelareh, Tymianski, Mike, Rauramaa, Tuomas, Ylä-Herttuala, Seppo, Wythe, Joshua D, Antonarakis, Stylianos E, Frösen, Juhana, Fish, Jason E, Radovanovic, Ivan
Published in The New England journal of medicine (18.01.2018)
Published in The New England journal of medicine (18.01.2018)
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Journal Article
Phylogenetic position of Multicilia marina and the evolution of Amoebozoa
Nikolaev, Sergey I, Berney, Cedric, Petrov, Nikolai B, Mylnikov, Alexandre P, Fahrni, Jose F, Pawlowski, Jan
Published in International journal of systematic and evolutionary microbiology (01.06.2006)
Published in International journal of systematic and evolutionary microbiology (01.06.2006)
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Journal Article
Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma
Bonilla, Ximena, Parmentier, Laurent, King, Bryan, Bezrukov, Fedor, Kaya, Gürkan, Zoete, Vincent, Seplyarskiy, Vladimir B, Sharpe, Hayley J, McKee, Thomas, Letourneau, Audrey, Ribaux, Pascale G, Popadin, Konstantin, Basset-Seguin, Nicole, Chaabene, Rouaa Ben, Santoni, Federico A, Andrianova, Maria A, Guipponi, Michel, Garieri, Marco, Verdan, Carole, Grosdemange, Kerstin, Sumara, Olga, Eilers, Martin, Aifantis, Iannis, Michielin, Olivier, de Sauvage, Frederic J, Antonarakis, Stylianos E, Nikolaev, Sergey I
Published in Nature genetics (01.04.2016)
Published in Nature genetics (01.04.2016)
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Journal Article
Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma
Nikolaev, Sergey I, Rimoldi, Donata, Iseli, Christian, Valsesia, Armand, Robyr, Daniel, Gehrig, Corinne, Harshman, Keith, Guipponi, Michel, Bukach, Olesya, Zoete, Vincent, Michielin, Olivier, Muehlethaler, Katja, Speiser, Daniel, Beckmann, Jacques S, Xenarios, Ioannis, Halazonetis, Thanos D, Jongeneel, C Victor, Stevenson, Brian J, Antonarakis, Stylianos E
Published in Nature genetics (01.02.2012)
Published in Nature genetics (01.02.2012)
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Journal Article
Evolutionary Forces Shape the Human RFPL1,2,3 Genes toward a Role in Neocortex Development
Bonnefont, Jérôme, Nikolaev, Sergey I., Perrier, Anselme L., Guo, Song, Cartier, Laetitia, Sorce, Silvia, Laforge, Térèse, Aubry, Laetitia, Khaitovich, Philipp, Peschanski, Marc, Antonarakis, Stylianos E., Krause, Karl-Heinz
Published in American journal of human genetics (01.08.2008)
Published in American journal of human genetics (01.08.2008)
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Journal Article
Detection of genomic variation by selection of a 9 mb DNA region and high throughput sequencing
Nikolaev, Sergey I, Iseli, Christian, Sharp, Andrew J, Robyr, Daniel, Rougemont, Jacques, Gehrig, Corinne, Farinelli, Laurent, Antonarakis, Stylianos E
Published in PloS one (17.08.2009)
Published in PloS one (17.08.2009)
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Journal Article
Resistance to selective FGFR inhibitors in FGFR-driven urothelial cancer
Facchinetti, Francesco, Hollebecque, Antoine, Braye, Floriane, Vasseur, Damien, Pradat, Yoann, Bahleda, Rastislav, Pobel, Cedric, Bigot, Ludovic, Deas, Olivier, Florez Arango, Juan David, Guaitoli, Giorgia, Mizuta, Hayato, Combarel, David, Tselikas, Lambros, Michiels, Stefan, Nikolaev, Sergey I, Scoazec, Jean-Yves, Ponce-Aix, Santiago, Besse, Benjamin, Olaussen, Ken A, Loriot, Yohann, Friboulet, Luc
Published in Cancer discovery (06.09.2023)
Published in Cancer discovery (06.09.2023)
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Journal Article
Exome sequencing identifies putative drivers of progression of transient myeloproliferative disorder to AMKL in infants with Down syndrome
Nikolaev, Sergey I., Santoni, Federico, Vannier, Anne, Falconnet, Emilie, Giarin, Emanuela, Basso, Giuseppe, Hoischen, Alexander, Veltman, Joris A., Groet, Jurgen, Nizetic, Dean, Antonarakis, Stylianos E.
Published in Blood (25.07.2013)
Published in Blood (25.07.2013)
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Integrative Pan-Cancer Genomic and Transcriptomic Analyses of Refractory Metastatic Cancer
Pradat, Yoann, Viot, Julien, Yurchenko, Andrey A, Gunbin, Konstantin, Cerbone, Luigi, Deloger, Marc, Grisay, Guillaume, Verlingue, Loic, Scott, Véronique, Padioleau, Ismael, Panunzi, Leonardo, Michiels, Stefan, Hollebecque, Antoine, Jules-Clément, Gérôme, Mezquita, Laura, Lainé, Antoine, Loriot, Yohann, Besse, Benjamin, Friboulet, Luc, André, Fabrice, Cournède, Paul-Henry, Gautheret, Daniel, Nikolaev, Sergey I
Published in Cancer discovery (04.05.2023)
Published in Cancer discovery (04.05.2023)
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Journal Article
Frequent cases of RAS-mutated Down syndrome acute lymphoblastic leukaemia lack JAK2 mutations
Nikolaev, Sergey I., Garieri, Marco, Santoni, Federico, Falconnet, Emilie, Ribaux, Pascale, Guipponi, Michel, Murray, Aoife, Groet, Jürgen, Giarin, Emanuela, Basso, Giuseppe, Nizetic, Dean, Antonarakis, Stylianos E.
Published in Nature communications (08.08.2014)
Published in Nature communications (08.08.2014)
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