Light-Induced Modular Ligation of Conventional RAFT Polymers
Oehlenschlaeger, Kim K., Mueller, Jan O., Heine, Niklas B., Glassner, Mathias, Guimard, Nathalie K., Delaittre, Guillaume, Schmidt, Friedrich G., Barner-Kowollik, Christopher
Published in Angewandte Chemie International Edition (07.01.2013)
Published in Angewandte Chemie International Edition (07.01.2013)
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Journal Article
Efficient Modular Synthesis of Isomeric Mono- and Bispyridyl[2.2]paracyclophanes by Palladium-Catalyzed Cross- Coupling Reactions
Braun, Carolin, Spuling, Eduard, Heine, Niklas B., Cakici, Murat, Nieger, Martin, Bräse, Stefan
Published in Advanced synthesis & catalysis (19.05.2016)
Published in Advanced synthesis & catalysis (19.05.2016)
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Journal Article
Synthesis of Chiral Piperazinones Using Amphoteric Aziridine Aldehyde Dimers and Functionalized Isocyanides
Heine, Niklas B, Kaldas, Sherif J, Belding, Lee, Shmatova, Olga, Dudding, Travis, Nenajdenko, Valentine G, Studer, Armido, Yudin, Andrei K
Published in Journal of organic chemistry (17.06.2016)
Published in Journal of organic chemistry (17.06.2016)
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Journal Article
Efficient assembly of peptomers on continuous surfaces
Ast, Thomas, Heine, Niklas, Germeroth, Lothar, Schneider-Mergener, Jens, Wenschuh, Holger
Published in Tetrahedron letters (04.06.1999)
Published in Tetrahedron letters (04.06.1999)
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Journal Article
Identification of Highly Selective Orexin 1 Receptor Antagonists Driven by Structure-Based Design
Lessel, Uta, Ferrara, Marco, Heine, Niklas, Marelli, Chiara, Carrettoni, Laura, Pfau, Roland, Schmidt, Esther, Riether, Doris
Published in Journal of chemical information and modeling (27.12.2021)
Published in Journal of chemical information and modeling (27.12.2021)
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Journal Article
Discovery of BI-9787, a potent zwitterionic ketohexokinase inhibitor with oral bioavailability
Heine, Niklas, Weber, Alexander, Pautsch, Alexander, Gottschling, Dirk, Uphues, Ingo, Bauer, Margit, Ebenhoch, Rebecca, Magarkar, Aniket, Nosse, Bernd, Kley, Jörg Thomas
Published in Bioorganic & medicinal chemistry letters (01.11.2024)
Published in Bioorganic & medicinal chemistry letters (01.11.2024)
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Journal Article
Crystal structures of human and mouse ketohexokinase provide a structural basis for species‐ and isoform‐selective inhibitor design
Ebenhoch, Rebecca, Bauer, Margit, Romig, Helmut, Gottschling, Dirk, Kley, Jörg Thomas, Heine, Niklas, Weber, Alexander, Uphues, Ingo, Nar, Herbert, Pautsch, Alexander
Published in Acta crystallographica. Section D, Biological crystallography. (01.10.2023)
Published in Acta crystallographica. Section D, Biological crystallography. (01.10.2023)
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Journal Article
Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators
Gerlach, Kai, Hobson, Scott, Eickmeier, Christian, Groß, Ulrike, Braun, Clemens, Sieger, Peter, Garneau, Michel, Hoerer, Stefan, Heine, Niklas
Published in Bioorganic & medicinal chemistry (23.07.2018)
Published in Bioorganic & medicinal chemistry (23.07.2018)
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Journal Article
Lichtinduzierte modulare Ligation von konventionellen RAFT-Polymeren
Oehlenschlaeger, Kim K., Mueller, Jan O., Heine, Niklas B., Glassner, Mathias, Guimard, Nathalie K., Delaittre, Guillaume, Schmidt, Friedrich G., Barner-Kowollik, Christopher
Published in Angewandte Chemie (07.01.2013)
Published in Angewandte Chemie (07.01.2013)
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Journal Article
Process Development of the BACE Inhibitors BI 1147560 BS and BI 1181181 MZ
Li, Guisheng, Tan, Zhulin, Xu, Yibo, Sidhu, Kanwar P. S., Qu, Bo, Herbage, Melissa A., Eriksson, Magnus C., Zeng, Xingzhong, Busacca, Carl A., Desrosiers, Jean-Nicolas, Hampel, Thomas, Niemeier, Oliver, Reichel, Carsten, Quynh Dang, Mai Thi, Schoerer, Marvin, Kemmer, Dirk, Eick, Melanie, Werle, Holger, Kim, Soojin, Li, Zhibin, Venkatraman, Shankar, Jia, Lanqi, Claremon, David A., Fuchs, Klaus, Heine, Niklas, Byrne, Denis, Narayanan, Bikshandarkoil, Sarvestani, Max, Johnson, Joe, Premasiri, Ajith, Nummy, Larry J., Lorenz, Jon C., Haddad, Nizar, Gonnella, Nina C., Pennino, Scott, Krawiec, Mariusz, Senanayake, Chris H., Buono, Frederic, Lee, Heewon, Hossain, Azad, Song, Jinhua J., Reeves, Jonathan T.
Published in Organic process research & development (16.12.2022)
Published in Organic process research & development (16.12.2022)
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Journal Article
ChemInform Abstract: Synthesis of Chiral Piperazinones Using Amphoteric Aziridine Aldehyde Dimers and Functionalized Isocyanides
Heine, Niklas B., Kaldas, Sherif J., Belding, Lee, Shmatova, Olga, Dudding, Travis, Nenajdenko, Valentine G., Studer, Armido, Yudin, Andrei K.
Published in ChemInform (01.10.2016)
Published in ChemInform (01.10.2016)
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Journal Article
PYRIDINE CARBONYL DERIVATIVE AND THERAPEUTIC USE THEREOF AS TRPC6 INHIBITOR
CHRISTOPHER RONALD SARKO, TURNER MICHAEL R, MICHAEL D LOWE, HOSSEIN RAZAVI, WU XINYUAN, NIKLAS HEINE, TAKAHASHI SHUSUKE, LANA LOUISE SMITH KEENAN, SIMON SURPRENANT, DIRK GOTTSCHLING, THIERRY BOUYSSOU
Year of Publication 28.01.2021
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Year of Publication 28.01.2021
Patent
Synthesis and screening of peptoid arrays on cellulose membranes
Heine, Niklas, Ast, Thomas, Schneider-Mergener, Jens, Reineke, Ulrich, Germeroth, Lothar, Wenschuh, Holger
Published in Tetrahedron (08.12.2003)
Published in Tetrahedron (08.12.2003)
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Journal Article
INHIBITORS OF -SECRETASE
DAVID A CLAREMON, LAWRENCE W DILLARD, NIKLAS HEINE, SALVACION CACATIAN, ANGEL MORALES-RAMOS, ZHENG YAJUN, WU ZHONGREN, LANQI JIA, KATERINA LEFTHERIS, SHANKAR VENKATRAMAN, YUAN JING, XU ZHENRONG, KLAUS FUCHS, SINGH SURESH, WU GUOXIAN, BRIAN MCKEEVER
Year of Publication 20.08.2015
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Year of Publication 20.08.2015
Patent