The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling
Taipale, Jussi, Aaltonen, Lauri A, Tuupanen, Sari, Turunen, Mikko, Lehtonen, Rainer, Hallikas, Outi, Vanharanta, Sakari, Kivioja, Teemu, Björklund, Mikael, Wei, Gonghong, Yan, Jian, Niittymäki, Iina, Mecklin, Jukka-Pekka, Järvinen, Heikki, Ristimäki, Ari, Di-Bernardo, Mariachiara, East, Phil, Carvajal-Carmona, Luis, Houlston, Richard S, Tomlinson, Ian, Palin, Kimmo, Ukkonen, Esko, Karhu, Auli
Published in Nature genetics (01.08.2009)
Published in Nature genetics (01.08.2009)
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Allelic Imbalance at rs6983267 Suggests Selection of the Risk Allele in Somatic Colorectal Tumor Evolution
TUUPANEN, Sari, NIITTYMÄKI, Iina, NOUSIAINEN, Kari, VANHARANTA, Sakari, MECKLIN, Jukka-Pekka, NUORVA, Kyösti, JÄRVINEN, Heikki, HAUTANIEMI, Sampsa, KARHU, Auli, AALTONEN, Lauri A
Published in Cancer research (Chicago, Ill.) (2008)
Published in Cancer research (Chicago, Ill.) (2008)
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Mutations in the circadian gene CLOCK in colorectal cancer
Alhopuro, Pia, Björklund, Mikael, Sammalkorpi, Heli, Turunen, Mikko, Tuupanen, Sari, Biström, Mia, Niittymäki, Iina, Lehtonen, Heli J, Kivioja, Teemu, Launonen, Virpi, Saharinen, Juha, Nousiainen, Kari, Hautaniemi, Sampsa, Nuorva, Kyösti, Mecklin, Jukka-Pekka, Järvinen, Heikki, Orntoft, Torben, Arango, Diego, Lehtonen, Rainer, Karhu, Auli, Taipale, Jussi, Aaltonen, Lauri A
Published in Molecular cancer research (01.07.2010)
Published in Molecular cancer research (01.07.2010)
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Low-Penetrance Susceptibility Variants in Familial Colorectal Cancer
NIITTYMÄKI, Iina, KAASINEN, Eevi, TUUPANEN, Sari, KARHU, Auli, JÄRVINEN, Heikki, MECKLIN, Jukka-Pekka, TOMLINSON, Ian P. M, CHIARA DI BERNARDO, Maria, HOULSTON, Richard S, AALTONEN, Lauri A
Published in Cancer epidemiology, biomarkers & prevention (01.06.2010)
Published in Cancer epidemiology, biomarkers & prevention (01.06.2010)
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Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci
Niittymäki, Iina, Tuupanen, Sari, Li, Yilong, Järvinen, Heikki, Mecklin, Jukka-Pekka, Tomlinson, Ian P M, Houlston, Richard S, Karhu, Auli, Aaltonen, Lauri A
Published in BMC medical genetics (14.02.2011)
Published in BMC medical genetics (14.02.2011)
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High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle assembly checkpoint
NIITTYMAKI, Iina, GYLFE, Alexandra, NUORVA, Kyosti, MECKLIN, Jukka-Pekka, MÄKINEN, Markus, RISTIMÄKI, Ari, ØRNTOFT, Torben F, HAUTANIEMI, Sampsa, KARHU, Auli, KALLIO, Marko J, AALTONEN, Lauri A, LAINE, Leena, LAAKSO, Marko, LEHTONEN, Heli J, KONDELIN, Johanna, TOLVANEN, Jaana, NOUSIAINEN, Kari, POUWELS, Jeroen, JÄRVINEN, Heikki
Published in Carcinogenesis (New York) (01.03.2011)
Published in Carcinogenesis (New York) (01.03.2011)
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Mutation analysis of MYH11 in acute myeloid leukemia
Sammalkorpi, Heli, Alhopuro, Pia, Niittymäki, Iina, Ørntoft, Torben F., Hokland, Peter, Karhu, Auli, Aaltonen, Lauri A.
Published in Leukemia & lymphoma (01.01.2008)
Published in Leukemia & lymphoma (01.01.2008)
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Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33
Houlston, Richard S, Dunlop, Malcolm G, Tomlinson, Ian P M, Cheadle, Jeremy, Dobbins, Sara E, Tenesa, Albert, Jones, Angela M, Howarth, Kimberley, Spain, Sarah L, Broderick, Peter, Domingo, Enric, Farrington, Susan, Prendergast, James G D, Pittman, Alan M, Theodoratou, Evi, Smith, Christopher G, Olver, Bianca, Walther, Axel, Barnetson, Rebecca A, Churchman, Michael, Jaeger, Emma E M, Penegar, Steven, Barclay, Ella, Martin, Lynn, Gorman, Maggie, Mager, Rachel, Johnstone, Elaine, Midgley, Rachel, Niittymäki, Iina, Tuupanen, Sari, Colley, James, Idziaszczyk, Shelley, Thomas, Huw J W, Lucassen, Anneke M, Evans, D Gareth R, Maher, Eamonn R, Maughan, Timothy, Dimas, Antigone, Dermitzakis, Emmanouil, Cazier, Jean-Baptiste, Aaltonen, Lauri A, Pharoah, Paul, Kerr, David J, Carvajal-Carmona, Luis G, Campbell, Harry
Published in Nature genetics (01.11.2010)
Published in Nature genetics (01.11.2010)
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Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42 103 individuals
Dunlop, Malcolm G, Tenesa, Albert, Farrington, Susan M, Ballereau, Stephane, Brewster, David H, Koessler, Thibaud, Pharoah, Paul, Schafmayer, Clemens, Hampe, Jochen, Völzke, Henry, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, von Holst, Susanna, Picelli, Simone, Lindblom, Annika, Jenkins, Mark A, Hopper, John L, Casey, Graham, Duggan, David, Newcomb, Polly A, Abulí, Anna, Bessa, Xavier, Ruiz-Ponte, Clara, Castellví-Bel, Sergi, Niittymäki, Iina, Tuupanen, Sari, Karhu, Auli, Aaltonen, Lauri, Zanke, Brent, Hudson, Tom, Gallinger, Steven, Barclay, Ella, Martin, Lynn, Gorman, Maggie, Carvajal-Carmona, Luis, Walther, Axel, Kerr, David, Lubbe, Steven, Broderick, Peter, Chandler, Ian, Pittman, Alan, Penegar, Steven, Campbell, Harry, Tomlinson, Ian, Houlston, Richard S
Published in Gut (01.06.2013)
Published in Gut (01.06.2013)
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Candidate driver genes in microsatellite-unstable colorectal cancer
Alhopuro, Pia, Sammalkorpi, Heli, Niittymäki, Iina, Biström, Mia, Raitila, Anniina, Saharinen, Juha, Nousiainen, Kari, Lehtonen, Heli J., Heliövaara, Elina, Puhakka, Jani, Tuupanen, Sari, Sousa, Sónia, Seruca, Raquel, Ferreira, Ana M., Hofstra, Robert M. W., Mecklin, Jukka-Pekka, Järvinen, Heikki, Ristimäki, Ari, Ørntoft, Torben F., Hautaniemi, Sampsa, Arango, Diego, Karhu, Auli, Aaltonen, Lauri A.
Published in International journal of cancer (01.04.2012)
Published in International journal of cancer (01.04.2012)
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Abstract 3864: Low-penetrance variants underlying familial colorectal cancer
Niittymäki, Iina, Kaasinen, Eevi, Karhu, Auli, Järvinen, Heikki, Mecklin, Jukka-Pekka, Tomlinson, Ian PM, Houlston, Richard S., Aaltonen, Lauri A.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Abstract A57: Nonsense-mediated decay escaping mutations in microsatellite-unstable colorectal cancer
Gylfe, Alexandra, Niittymäki, Iina, Ahonen, Leena, Lehtonen, Heli, Laakso, Marko, Sirkiä, Johanna, Nousiainen, Kari, Pouwels, Jeroen, Järvinen, Heikki, Nuorva, Kyösti, Mecklin, Jukka-Pekka, Ristimäki, Ari, Ørntoft, Torben, Hautaniemi, Sampsa, Karhu, Auli, Kallio, Marko, Aaltonen, Lauri
Published in Cancer research (Chicago, Ill.) (01.12.2009)
Published in Cancer research (Chicago, Ill.) (01.12.2009)
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COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer
Tomlinson, Ian P, Dunlop, Malcolm, Campbell, Harry, Zanke, Brent, Gallinger, Steven, Hudson, Thomas J, Koessler, Thibaud, Pharoah, Paul D. P, Niittymäki, Iina, Tuupanen, Sari, Aaltonen, Lauri A, Hemminki, Kari, Lindblom, Annika, Försti, Asta, Sieber, Oliver, Lipton, Lara, Van Wezel, Tom, Morreau, Hans, Wijnen, Juul, Devilee, Peter, Matsuda, Kenji, Nakamura, Yusuke, Castellví-Bel, Sergi, Ruiz-Ponte, Clara, Castells Garangou, Antoni, Carracedo Álvarez, Ángel, Ho, J.W, Sham, Pak Chung, Hofstra, Robert, Vodicka, Pavel, Brenner, Hermann, Hampe, Jochen, Schafmayer, Clemens, Tepel, Juergen, Schreiber, Stefan, Völzke, Henry, Lerch, Markus M, Schmidt, Christian A, Buch, Stephan, Moreno Aguado, Víctor
Published in British journal of cancer (15.07.2010)
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Published in British journal of cancer (15.07.2010)
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