Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature
Wolking, Stefan, Schaeffeler, Elke, Lerche, Holger, Schwab, Matthias, Nies, Anne T.
Published in Clinical pharmacokinetics (01.07.2015)
Published in Clinical pharmacokinetics (01.07.2015)
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Journal Article
Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs)
Nies, Anne T, Hofmann, Ute, Resch, Claudia, Schaeffeler, Elke, Rius, Maria, Schwab, Matthias
Published in PloS one (14.07.2011)
Published in PloS one (14.07.2011)
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Journal Article
Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver
Nies, Anne T., Koepsell, Hermann, Winter, Stefan, Burk, Oliver, Klein, Kathrin, Kerb, Reinhold, Zanger, Ulrich M., Keppler, Dietrich, Schwab, Matthias, Schaeffeler, Elke
Published in Hepatology (Baltimore, Md.) (01.10.2009)
Published in Hepatology (Baltimore, Md.) (01.10.2009)
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Journal Article
A phosphotyrosine switch regulates organic cation transporters
Sprowl, Jason A., Ong, Su Sien, Gibson, Alice A., Hu, Shuiying, Du, Guoqing, Lin, Wenwei, Li, Lie, Bharill, Shashank, Ness, Rachel A., Stecula, Adrian, Offer, Steven M., Diasio, Robert B., Nies, Anne T., Schwab, Matthias, Cavaletti, Guido, Schlatter, Eberhard, Ciarimboli, Giuliano, Schellens, Jan H. M., Isacoff, Ehud Y., Sali, Andrej, Chen, Taosheng, Baker, Sharyn D., Sparreboom, Alex, Pabla, Navjotsingh
Published in Nature communications (16.03.2016)
Published in Nature communications (16.03.2016)
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Journal Article
Role of ABC Transporters in Fluoropyrimidine-Based Chemotherapy Response
Nies, Anne T, Magdy, Tarek, Schwab, Matthias, Zanger, Ulrich M
Published in ABC Transporters and Cancer (2015)
Published in ABC Transporters and Cancer (2015)
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Book Chapter
Journal Article
Inhibition of organic cation transporter 3 activity by tyrosine kinase inhibitors
Alim, Karima, Moreau, Amélie, Bruyère, Arnaud, Jouan, Elodie, Denizot, Claire, Nies, Anne T., Parmentier, Yannick, Fardel, Olivier
Published in Fundamental & clinical pharmacology (01.10.2021)
Published in Fundamental & clinical pharmacology (01.10.2021)
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Journal Article
Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation
Nies, Anne T., König, Jörg, Leuthold, Patrick, Damme, Katja, Winter, Stefan, Haag, Mathias, Masuda, Satohiro, Kruck, Stephan, Daniel, Hannelore, Spanier, Britta, Fromm, Martin F., Bedke, Jens, Inui, Ken-ichi, Schwab, Matthias, Schaeffeler, Elke
Published in Pharmacological research (01.10.2023)
Published in Pharmacological research (01.10.2023)
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Journal Article
Interaction of Remdesivir with Clinically Relevant Hepatic Drug Uptake Transporters
Nies, Anne T, König, Jörg, Hofmann, Ute, Kölz, Charlotte, Fromm, Martin F, Schwab, Matthias
Published in Pharmaceutics (10.03.2021)
Published in Pharmaceutics (10.03.2021)
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Journal Article
Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation
Tremmel, Roman, Nies, Anne T., van Eijck, Barbara A. C., Handin, Niklas, Haag, Mathias, Winter, Stefan, Büttner, Florian A., Kölz, Charlotte, Klein, Franziska, Mazzola, Pascale, Hofmann, Ute, Klein, Kathrin, Hoffmann, Per, Nöthen, Markus M., Gaugaz, Fabienne Z., Artursson, Per, Schwab, Matthias, Schaeffeler, Elke
Published in International journal of molecular sciences (01.07.2022)
Published in International journal of molecular sciences (01.07.2022)
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Journal Article
ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier
BRONGER, Holger, KÖNIG, Jörg, KOPPLOW, Kathrin, STEINER, Hans-Herbert, AHMADI, Rezvan, HEROLD-MENDE, Christel, KEPPLER, Dietrich, NIES, Anne T
Published in Cancer research (Chicago, Ill.) (15.12.2005)
Published in Cancer research (Chicago, Ill.) (15.12.2005)
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Journal Article
Mammalian MATE (SLC47A) transport proteins: impact on efflux of endogenous substrates and xenobiotics
Damme, Katja, Nies, Anne T., Schaeffeler, Elke, Schwab, Matthias
Published in Drug metabolism reviews (01.11.2011)
Published in Drug metabolism reviews (01.11.2011)
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Journal Article
The importance of drug transporter characterization to precision medicine
Fisel, Pascale, Nies, Anne T, Schaeffeler, Elke, Schwab, Matthias
Published in Expert opinion on drug metabolism & toxicology (03.04.2017)
Published in Expert opinion on drug metabolism & toxicology (03.04.2017)
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Journal Article
Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1)
Nies, Anne T., Herrmann, Elke, Brom, Manuela, Keppler, Dietrich
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.02.2008)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.02.2008)
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Journal Article
The Membrane Transporter OAT7 (SLC22A9) Is Not a Susceptibility Factor for Osteoporosis in Europeans
Nies, Anne T, Weiss, Stefan, Schaeffeler, Elke, Hannemann, Anke, Völker, Uwe, Wallaschofski, Henri, Schwab, Matthias
Published in Frontiers in endocrinology (Lausanne) (18.08.2020)
Published in Frontiers in endocrinology (Lausanne) (18.08.2020)
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Journal Article
Effects of a Common Eight Base Pairs Duplication at the Exon 7-Intron 7 Junction on Splicing, Expression, and Function of OCT1
Römer, Sarah, Meyer, Marleen J., Klein, Kathrin, Schneider, Lennart V., Matthaei, Johannes, Tzvetkova, Ana, Łapczuk-Romańska, Joanna, Gaedcke, Jochen, Droździk, Marek, Brockmöller, Jürgen, Nies, Anne T., Tzvetkov, Mladen V.
Published in Frontiers in pharmacology (07.05.2021)
Published in Frontiers in pharmacology (07.05.2021)
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Journal Article