Preclinical activity of nanoliposomal irinotecan is governed by tumor deposition and intratumor prodrug conversion
Kalra, Ashish V, Kim, Jaeyeon, Klinz, Stephan G, Paz, Nancy, Cain, Jason, Drummond, Daryl C, Nielsen, Ulrik B, Fitzgerald, Jonathan B
Published in Cancer research (Chicago, Ill.) (01.12.2014)
Published in Cancer research (Chicago, Ill.) (01.12.2014)
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Journal Article
Identification and high-throughput genotyping of single nucleotide polymorphism markers in a non-model conifer (Abies nordmanniana (Steven) Spach)
Ousmael, Kedra, Whetten, Ross W., Xu, Jing, Nielsen, Ulrik B., Lamour, Kurt, Hansen, Ole K.
Published in Scientific reports (15.12.2023)
Published in Scientific reports (15.12.2023)
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Journal Article
Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data
Schoeberl, Birgit, Nielsen, Ulrik B, Niepel, Mario, Sorger, Peter K, Jasper, Paul J, Chen, William W, Lauffenburger, Douglas A
Published in Molecular systems biology (2009)
Published in Molecular systems biology (2009)
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Journal Article
Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis
Schoeberl, Birgit, Pace, Emily A, Fitzgerald, Jonathan B, Harms, Brian D, Xu, Lihui, Nie, Lin, Linggi, Bryan, Kalra, Ashish, Paragas, Violette, Bukhalid, Raghida, Grantcharova, Viara, Kohli, Neeraj, West, Kip A, Leszczyniecka, Magdalena, Feldhaus, Michael J, Kudla, Arthur J, Nielsen, Ulrik B
Published in Science signaling (30.06.2009)
Published in Science signaling (30.06.2009)
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Journal Article
MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM
Casaletto, Jessica B., Geddie, Melissa L., Abu-Yousif, Adnan O., Masson, Kristina, Fulgham, Aaron, Boudot, Antoine, Maiwald, Tim, Kearns, Jeffrey D., Kohli, Neeraj, Su, Stephen, Razlog, Maja, Raue, Andreas, Kalra, Ashish, Håkansson, Maria, Logan, Derek T., Welin, Martin, Chattopadhyay, Shrikanta, Harms, Brian D., Nielsen, Ulrik B., Schoeberl, Birgit, Lugovskoy, Alexey A., MacBeath, Gavin
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2019)
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Journal Article
Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302)
Geretti, Elena, Leonard, Shannon Curtis, Dumont, Nancy, Lee, Helen, Zheng, Jinzi, De Souza, Raquel, Gaddy, Daniel F, Espelin, Christopher W, Jaffray, David A, Moyo, Victor, Nielsen, Ulrik B, Wickham, Thomas J, Hendriks, Bart S
Published in Molecular cancer therapeutics (01.09.2015)
Published in Molecular cancer therapeutics (01.09.2015)
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Journal Article
HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B
Kirouac, Daniel C, Du, Jinyan, Lahdenranta, Johanna, Onsum, Matthew D, Nielsen, Ulrik B, Schoeberl, Birgit, McDonagh, Charlotte F
Published in PLoS computational biology (01.04.2016)
Published in PLoS computational biology (01.04.2016)
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Journal Article
Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies
Zhou, Yu, Goenaga, Anne-Laure, Harms, Brian D, Zou, Hao, Lou, Jianlong, Conrad, Fraser, Adams, Gregory P, Schoeberl, Birgit, Nielsen, Ulrik B, Marks, James D
Published in Molecular cancer therapeutics (01.07.2012)
Published in Molecular cancer therapeutics (01.07.2012)
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Journal Article
Insulin‐Like Growth Factor Promotes Cardiac Lineage Induction In Vitro by Selective Expansion of Early Mesoderm
Engels, Marc C., Rajarajan, Kuppusamy, Feistritzer, Rebecca, Sharma, Arun, Nielsen, Ulrik B., Schalij, Martin J., Vries, Antoine A.F., Pijnappels, Daniël A., Wu, Sean M.
Published in Stem cells (Dayton, Ohio) (01.06.2014)
Published in Stem cells (Dayton, Ohio) (01.06.2014)
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Journal Article
The Response of Human Epithelial Cells to TNF Involves an Inducible Autocrine Cascade
Janes, Kevin A., Gaudet, Suzanne, Albeck, John G., Nielsen, Ulrik B., Lauffenburger, Douglas A., Sorger, Peter K.
Published in Cell (24.03.2006)
Published in Cell (24.03.2006)
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Journal Article
Multiplexed sandwich assays in microarray format
Nielsen, Ulrik B, Geierstanger, Bernhard H
Published in Journal of Immunological Methods (01.07.2004)
Published in Journal of Immunological Methods (01.07.2004)
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Book Review
Journal Article
Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle
Zhang, Kathy, Geddie, Melissa L, Kohli, Neeraj, Kornaga, Tad, Kirpotin, Dmitri B, Jiao, Yang, Rennard, Rachel, Drummond, Daryl C, Nielsen, Ulrik B, Xu, Lihui, Lugovskoy, Alexey A
Published in mAbs (01.01.2015)
Published in mAbs (01.01.2015)
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Journal Article
Selection of tumor-specific internalizing human antibodies from phage libraries
Poul, Marie-Alix, Becerril, Baltazar, Nielsen, Ulrik B, Morisson, Peter, Marks, James D
Published in Journal of molecular biology (01.09.2000)
Published in Journal of molecular biology (01.09.2000)
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Journal Article
Systems biology and combination therapy in the quest for clinical efficacy
Sorger, Peter K, Fitzgerald, Jonathan B, Schoeberl, Birgit, Nielsen, Ulrik B
Published in Nature chemical biology (01.09.2006)
Published in Nature chemical biology (01.09.2006)
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Journal Article
Reviewing emerging markets: context, concepts and future research
Nielsen, Ulrik B, Hannibal, Martin, Larsen, Nathalie N
Published in International journal of emerging markets (29.11.2018)
Published in International journal of emerging markets (29.11.2018)
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Journal Article
Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3
McDonagh, Charlotte F, Huhalov, Alexandra, Harms, Brian D, Adams, Sharlene, Paragas, Violette, Oyama, Shinji, Zhang, Bo, Luus, Lia, Overland, Ryan, Nguyen, Stephanie, Gu, Jinming, Kohli, Neeraj, Wallace, Matt, Feldhaus, Michael J, Kudla, Arthur J, Schoeberl, Birgit, Nielsen, Ulrik B
Published in Molecular cancer therapeutics (01.03.2012)
Published in Molecular cancer therapeutics (01.03.2012)
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Journal Article
Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models
Kirpotin, Dmitri B, Drummond, Daryl C, Shao, Yi, Shalaby, M Refaat, Hong, Keelung, Nielsen, Ulrik B, Marks, James D, Benz, Christopher C, Park, John W
Published in Cancer research (Chicago, Ill.) (01.07.2006)
Published in Cancer research (Chicago, Ill.) (01.07.2006)
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Journal Article