The support of human genetic evidence for approved drug indications
Nelson, Matthew R, Tipney, Hannah, Painter, Jeffery L, Shen, Judong, Nicoletti, Paola, Shen, Yufeng, Floratos, Aris, Sham, Pak Chung, Li, Mulin Jun, Wang, Junwen, Cardon, Lon R, Whittaker, John C, Sanseau, Philippe
Published in Nature genetics (01.08.2015)
Published in Nature genetics (01.08.2015)
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Journal Article
Elucidating Compound Mechanism of Action by Network Perturbation Analysis
Woo, Jung Hoon, Shimoni, Yishai, Yang, Wan Seok, Subramaniam, Prem, Iyer, Archana, Nicoletti, Paola, Rodríguez Martínez, María, López, Gonzalo, Mattioli, Michela, Realubit, Ronald, Karan, Charles, Stockwell, Brent R., Bansal, Mukesh, Califano, Andrea
Published in Cell (16.07.2015)
Published in Cell (16.07.2015)
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Journal Article
Polygenic architecture informs potential vulnerability to drug-induced liver injury
Koido, Masaru, Kawakami, Eri, Fukumura, Junko, Noguchi, Yui, Ohori, Momoko, Nio, Yasunori, Nicoletti, Paola, Aithal, Guruprasad P., Daly, Ann K., Watkins, Paul B., Anayama, Hisashi, Dragan, Yvonne, Shinozawa, Tadahiro, Takebe, Takanori
Published in Nature medicine (01.10.2020)
Published in Nature medicine (01.10.2020)
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Journal Article
Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles
Nicoletti, Paola, Aithal, Guruprasad P, Chamberlain, Thomas C, Coulthard, Sally, Alshabeeb, Mohammad, Grove, Jane I, Andrade, Raul J, Bjornsson, Einar, Dillon, John F, Hallberg, Par, Lucena, M Isabel, Maitland-van der Zee, Anke H, Martin, Jennifer H, Molokhia, Mariam, Pirmohamed, Munir, Wadelius, Mia, Shen, Yufeng, Nelson, Matthew R, Daly, Ann K
Published in Clinical pharmacology and therapeutics (01.07.2019)
Published in Clinical pharmacology and therapeutics (01.07.2019)
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Journal Article
CGRP receptors in the control of pain and inflammation
Benemei, Silvia, Nicoletti, Paola, Capone, Jay G, Geppetti, Pierangelo
Published in Current opinion in pharmacology (01.02.2009)
Published in Current opinion in pharmacology (01.02.2009)
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Journal Article
Urinary Exosomes Identify Inflammatory Pathways in Vancomycin Associated Acute Kidney Injury
Awdishu, Linda, Le, Amy, Amato, Jordan, Jani, Vidhyut, Bal, Soma, Mills, Robert H, Carrillo-Terrazas, Marvic, Gonzalez, David J, Tolwani, Ashita, Acharya, Anjali, Cerda, Jorge, Joy, Melanie S, Nicoletti, Paola, Macedo, Etienne, Vaingankar, Sucheta, Mehta, Ravindra, RamachandraRao, Satish P, On Behalf Of The Direct Investigators
Published in International journal of molecular sciences (10.03.2021)
Published in International journal of molecular sciences (10.03.2021)
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Journal Article
Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice
Grant, Andrew D., Cottrell, Graeme S., Amadesi, Silvia, Trevisani, Marcello, Nicoletti, Paola, Materazzi, Serena, Altier, Christophe, Cenac, Nicolas, Zamponi, Gerald W., Bautista‐Cruz, Francisco, Lopez, Carlos Barajas, Joseph, Elizabeth K., Levine, Jon D., Liedtke, Wolfgang, Vanner, Stephen, Vergnolle, Nathalie, Geppetti, Pierangelo, Bunnett, Nigel W.
Published in The Journal of physiology (01.02.2007)
Published in The Journal of physiology (01.02.2007)
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Journal Article
The transient receptor potential vanilloid 1: Role in airway inflammation and disease
Geppetti, Pierangelo, Materazzi, Serena, Nicoletti, Paola
Published in European journal of pharmacology (08.03.2006)
Published in European journal of pharmacology (08.03.2006)
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Journal Article
Pharmacogenetics in Italy: current landscape and future prospects
Floris, Matteo, Moschella, Antonino, Alcalay, Myriam, Montella, Annalaura, Tirelli, Matilde, Fontana, Laura, Idda, Maria Laura, Guarnieri, Paolo, Capasso, Mario, Mammì, Corrado, Nicoletti, Paola, Miozzo, Monica
Published in Human genomics (10.07.2024)
Published in Human genomics (10.07.2024)
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Journal Article
ABC transporters and the proteasome complex are implicated in susceptibility to Stevens-Johnson syndrome and toxic epidermal necrolysis across multiple drugs
Nicoletti, Paola, Bansal, Mukesh, Lefebvre, Celine, Guarnieri, Paolo, Shen, Yufeng, Pe'er, Itsik, Califano, Andrea, Floratos, Aris
Published in PloS one (25.06.2015)
Published in PloS one (25.06.2015)
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Journal Article
Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi‐Ethnic Allele and Copy Number Variant Detection
Scott, Stuart A., Scott, Erick R., Seki, Yoshinori, Chen, Annette J., Wallsten, Richard, Owusu Obeng, Aniwaa, Botton, Mariana R., Cody, Neal, Shi, Huanzhi, Zhao, Geping, Brake, Paul, Nicoletti, Paola, Yang, Yao, Delio, Maria, Shi, Lisong, Kornreich, Ruth, Schadt, Eric E., Edelmann, Lisa
Published in Clinical and translational science (01.01.2021)
Published in Clinical and translational science (01.01.2021)
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Journal Article
Hydrogen sulfide causes vanilloid receptor 1‐mediated neurogenic inflammation in the airways
Trevisani, Marcello, Patacchini, Riccardo, Nicoletti, Paola, Gatti, Raffaele, Gazzieri, David, Lissi, Nicola, Zagli, Giovanni, Creminon, Christophe, Geppetti, Pierangelo, Harrison, Selena
Published in British journal of pharmacology (01.08.2005)
Published in British journal of pharmacology (01.08.2005)
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Journal Article
Identifying the Potential Mechanism of Action of SNPs Associated With Breast Cancer Susceptibility With GVITamIN
Nguyen, An-Phi, Nicoletti, Paola, Arnol, Damien, Califano, Andrea, Rodríguez Martínez, María
Published in Frontiers in bioengineering and biotechnology (04.08.2020)
Published in Frontiers in bioengineering and biotechnology (04.08.2020)
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Journal Article
The Influence of Alpha1 -Adrenoreceptors on Neuropeptide Release from Primary Sensory Neurons of the Lower Urinary Tract
Trevisani, Marcello, Campi, Barbara, Gatti, Raffaele, André, Eunice, Materazzi, Serena, Nicoletti, Paola, Gazzieri, David, Geppetti, Pierangelo
Published in European urology (01.09.2007)
Published in European urology (01.09.2007)
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Journal Article
Erratum to “Uterine Tumor Resembling Ovarian Sex Cord Tumors Type II with Vaginal Vault Recurrence”
Piccione, Emilio, Sesti, Francesco, Patrizi, Lodovico, Pietropolli, Adalgisa, Facchetti, Simone, Mauriello, A., Nicoletti, Paola, Marrucci, Oriana, Ticconi, Carlo
Published in Case reports in obstetrics and gynecology (01.01.2020)
Published in Case reports in obstetrics and gynecology (01.01.2020)
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Journal Article
Genetic Polymorphisms Implicated in Nonalcoholic Liver Disease or Selected Other Disorders Have No Influence on Drug‐Induced Liver Injury
Bonkovsky, Herbert L., Severson, Tyler, Nicoletti, Paola, Barnhart, Huiman, Serrano, Jose, Chalasani, Naga, Fontana, Robert J., Watkins, Paul B., Navarro, Victor, Stolz, Andrew, Daly, Ann K., Aithal, Guruparasad P., Odin, Joseph
Published in Hepatology communications (01.08.2019)
Published in Hepatology communications (01.08.2019)
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Journal Article
Uterine Tumor Resembling Ovarian Sex Cord Tumors Type II with Vaginal Vault Recurrence
Piccione, Emilio, Ticconi, Carlo, Patrizi, Lodovico, Facchetti, Simone, Mauriello, A., Nicoletti, Paola, Marrucci, Oriana, Sesti, Francesco
Published in Case reports in obstetrics and gynecology (2019)
Published in Case reports in obstetrics and gynecology (2019)
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Journal Article
Experimental colitis modulates the functional properties of NMDA receptors in dorsal root ganglia neurons
Li, Jichang, McRoberts, James A, Ennes, Helena S, Trevisani, Marcello, Nicoletti, Paola, Mittal, Yash, Mayer, Emeran A
Published in American journal of physiology: Gastrointestinal and liver physiology (01.08.2006)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.08.2006)
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Journal Article
Response to Rollins and Abaza
Chalasani, Naga, Phillips, Elizabeth, Nicoletti, Paola
Published in The American journal of gastroenterology (01.02.2024)
Published in The American journal of gastroenterology (01.02.2024)
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Journal Article