Co-expression of GRK2 reveals a novel conformational state of the µ-opioid receptor
Nickolls, Sarah A, Humphreys, Sian, Clark, Mellissa, McMurray, Gordon
Published in PloS one (20.12.2013)
Published in PloS one (20.12.2013)
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Journal Article
Molecular Determinants of Melanocortin 4 Receptor Ligand Binding and MC4/MC3 Receptor Selectivity
Nickolls, Sarah A, Cismowski, Mary I, Wang, Xiaochuan, Wolff, Meira, Conlon, Paul J, Maki, Richard A
Published in The Journal of pharmacology and experimental therapeutics (01.03.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2003)
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Journal Article
Residues W320 and Y328 within the binding site of the μ-opioid receptor influence opiate ligand bias
Hothersall, J. Daniel, Torella, Rubben, Humphreys, Sian, Hooley, Monique, Brown, Alastair, McMurray, Gordon, Nickolls, Sarah A.
Published in Neuropharmacology (15.05.2017)
Published in Neuropharmacology (15.05.2017)
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Journal Article
Functional Selectivity of Melanocortin 4 Receptor Peptide and Nonpeptide Agonists: Evidence for Ligand-Specific Conformational States
Nickolls, Sarah A, Fleck, Beth, Hoare, Sam R J, Maki, Rich A
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2005)
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Journal Article
Design and Identification of a Novel, Functionally Subtype Selective GABAA Positive Allosteric Modulator (PF-06372865)
Owen, Robert M, Blakemore, David, Cao, Lishuang, Flanagan, Neil, Fish, Rebecca, Gibson, Karl R, Gurrell, Rachel, Huh, Chan Woo, Kammonen, Juha, Mortimer-Cassen, Elisabeth, Nickolls, Sarah A, Omoto, Kiyoyuki, Owen, Dafydd, Pike, Andy, Pryde, David C, Reynolds, David S, Roeloffs, Rosemarie, Rose, Colin, Stead, Clara, Takeuchi, Mifune, Warmus, Joseph S, Watson, Christine
Published in Journal of medicinal chemistry (27.06.2019)
Published in Journal of medicinal chemistry (27.06.2019)
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Journal Article
Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABAA receptor positive allosteric modulator PF‐06372865
Nickolls, Sarah A, Gurrell, Rachel, Amerongen, Guido, Kammonen, Juha, Cao, Lishuang, Brown, Adam R, Stead, Clara, Mead, Andy, Watson, Christine, Hsu, Cathleen, Owen, Robert M, Pike, Andy, Fish, Rebecca L, Chen, Laigao, Qiu, Ruolun, Morris, Evan D, Feng, Gang, Whitlock, Mark, Gorman, Donal, Gerven, Joop, Reynolds, David S, Dua, Pinky, Butt, Richard P
Published in British journal of pharmacology (01.02.2018)
Published in British journal of pharmacology (01.02.2018)
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Journal Article
Design and Identification of a Novel, Functionally Subtype Selective GABA(A) Positive Allosteric Modulator (PF-06372865)
Owen, Robert M., Blakemore, David, Cao, Lishuan, Flanagan, Neil, Fish, Rebecca, Gibson, Karl R., Gurrell, Rachel, Huh, Chan Woo, Kammonen, Juha, Mortimer-Cassen, Elisabeth, Nickolls, Sarah A., Omoto, Kiyoyuki, Owen, Dafydd, Pike, Andy, Pryde, David C., Reynolds, David S., Roeloffs, Rosemarie, Rose, Colin, Stead, Clara, Takeuchi, Mifune, Warmus, Joseph S., Watson, Christine
Published in Journal of medicinal chemistry (27.06.2019)
Published in Journal of medicinal chemistry (27.06.2019)
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Journal Article
A potential role for cannabinoid receptors in the therapeutic action of fenofibrate
Priestley, Richard S, Nickolls, Sarah A, Alexander, Stephen P H, Kendall, David A
Published in The FASEB journal (01.04.2015)
Published in The FASEB journal (01.04.2015)
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Journal Article
Identification of CC Chemokine Receptor 7 Residues Important for Receptor Activation
Ott, Thomas R, Pahuja, Anil, Nickolls, Sarah A, Alleva, David G, Struthers, R Scott
Published in The Journal of biological chemistry (08.10.2004)
Published in The Journal of biological chemistry (08.10.2004)
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Journal Article
Identification of a novel BODIPY minihepcidin tool for the high content analysis of ferroportin (SLC40A1) pharmacology
Skerratt, Sarah. E, Humphreys, Sian, Ferreira, Rita, Jorgensen, Csilla, Warmus, Joe, Zhao, Lei, Tong, Xiaohe, Nickolls, Sarah A
Published in MedChemComm (11.08.2016)
Published in MedChemComm (11.08.2016)
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Journal Article
Molecular Interactions of Nonpeptide Agonists and Antagonists with the Melanocortin-4 Receptor
Fleck, Beth A, Chen, Yang, Weidong, Huntley, Rajesh, Markison, Stacy, Nickolls, Sarah A, Foster, Alan C, Hoare, Sam R. J
Published in Biochemistry (Easton) (08.11.2005)
Published in Biochemistry (Easton) (08.11.2005)
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Journal Article
Agonist Regulation of D2 Dopamine Receptor/G Protein Interaction
Cordeaux, Yolande, Nickolls, Sarah A., Flood, Lori A., Graber, Stephen G., Strange, Philip G.
Published in The Journal of biological chemistry (03.08.2001)
Published in The Journal of biological chemistry (03.08.2001)
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Journal Article
Co-Expression of GRK2 Reveals a Novel Conformational State of the [micro]-Opioid Receptor
Nickolls, Sarah A, Humphreys, Sian, Clark, Mellissa, McMurray, Gordon
Published in PloS one (20.12.2013)
Published in PloS one (20.12.2013)
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Journal Article
Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABA A receptor positive allosteric modulator PF-06372865
Nickolls, Sarah A, Gurrell, Rachel, van Amerongen, Guido, Kammonen, Juha, Cao, Lishuang, Brown, Adam R, Stead, Clara, Mead, Andy, Watson, Christine, Hsu, Cathleen, Owen, Robert M, Pike, Andy, Fish, Rebecca L, Chen, Laigao, Qiu, Ruolun, Morris, Evan D, Feng, Gang, Whitlock, Mark, Gorman, Donal, van Gerven, Joop, Reynolds, David S, Dua, Pinky, Butt, Richard P
Published in British journal of pharmacology (01.02.2018)
Published in British journal of pharmacology (01.02.2018)
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Journal Article