Action of chelators in iron-loaded cardiac cells: accessibility to intracellular labile iron and functional consequences
Glickstein, Hava, El, Rinat Ben, Link, Gabi, Breuer, William, Konijn, Abraham M., Hershko, Chaim, Nick, Hanspeter, Cabantchik, Z. Ioav
Published in Blood (01.11.2006)
Published in Blood (01.11.2006)
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Cardiac iron determines cardiac T2, T2, and T1 in the gerbil model of iron cardiomyopathy
WOOD, John C, OTTO-DUESSEL, Maya, AGUILAR, Michelle, NICK, Hanspeter, NELSON, Marvin D, COATES, Thomas D, POLLACK, Harvey, MOATS, Rex
Published in Circulation (New York, N.Y.) (26.07.2005)
Published in Circulation (New York, N.Y.) (26.07.2005)
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Journal Article
Pharmacokinetics, Distribution, Metabolism, and Excretion of Deferasirox and Its Iron Complex in Rats
BRUIN, Gerard J. M, FALLER, Thomas, WIEGAND, Hansjörg, SCHWEITZER, Alain, NICK, Hanspeter, SCHNEIDER, Josef, BOERNSEN, K.-Olaf, WALDMEIER, Felix
Published in Drug metabolism and disposition (01.12.2008)
Published in Drug metabolism and disposition (01.12.2008)
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Journal Article
Development of Tridentate Iron Chelators: From Desferrithiocin to ICL670
Nick, Hanspeter, Acklin, Pierre, Lattmann, René, Buehlmayer, Peter, Hauffe, Suzanne, Schupp, Joachim, Alberti, Daniele
Published in Current medicinal chemistry (01.06.2003)
Published in Current medicinal chemistry (01.06.2003)
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Identification of cardiac glycoside molecules as inhibitors of c-Myc IRES-mediated translation
Didiot, Marie-Cecile, Hewett, Jeffrey, Varin, Thibault, Freuler, Felix, Selinger, Douglas, Nick, Hanspeter, Reinhardt, Juergen, Buckler, Alan, Myer, Vic, Schuffenhauer, Ansgar, Guy, Chantale T, Parker, Christian N
Published in Journal of biomolecular screening (01.04.2013)
Published in Journal of biomolecular screening (01.04.2013)
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Journal Article
Deferasirox reduces iron overload in a murine model of juvenile hemochromatosis
Nick, Hanspeter, Allegrini, Peter R, Fozard, Lucy, Junker, Ursula, Rojkjaer, Lisa, Salie, Rishard, Niederkofler, Vera, O'Reilly, Terrence
Published in Experimental biology and medicine (Maywood, N.J.) (01.05.2009)
Published in Experimental biology and medicine (Maywood, N.J.) (01.05.2009)
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Journal Article
Comparison of twice-daily vs once-daily deferasirox dosing in a gerbil model of iron cardiomyopathy
Otto-Duessel, Maya, Aguilar, Michelle, Nick, Hanspeter, Moats, Rex, Wood, John C
Published in Experimental hematology (01.07.2007)
Published in Experimental hematology (01.07.2007)
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Journal Article
The new orally active iron chelator ICL670A exhibits a higher antiproliferative effect in human hepatocyte cultures than O-trensox
Chantrel-Groussard, Karine, Gaboriau, François, Pasdeloup, Nicole, Havouis, René, Nick, Hanspeter, Pierre, Jean-Louis, Brissot, Pierre, Lescoat, Gérard
Published in European journal of pharmacology (17.07.2006)
Published in European journal of pharmacology (17.07.2006)
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Journal Article
Ability of deferasirox to bind iron during measurement of iron
Lebitasy, Massin, Ampe, Els, Hecq, Jean-Daniel, Karmani, Linda, Nick, Hanspeter, Galanti, Laurence
Published in Clinical chemistry and laboratory medicine (01.03.2010)
Published in Clinical chemistry and laboratory medicine (01.03.2010)
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Journal Article
In vitro and in situ permeability of a 'second generation' hydroxypyridinone oral iron chelator : Correlation with physico-chemical properties and oral activity
LOWTHER, N, FOX, R, FALLER, B, NICK, H, YI JIN, SERGEJEW, T, HIRSCHBERG, Y, OBERLE, R, DONNELLY, H
Published in Pharmaceutical research (01.03.1999)
Published in Pharmaceutical research (01.03.1999)
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Journal Article
Reduction in labile plasma iron during treatment with deferasirox, a once-daily oral iron chelator, in heavily iron-overloaded patients with β-thalassaemia
Daar, Shahina, Pathare, Anil, Nick, Hanspeter, Kriemler-Krahn, Ulrike, Hmissi, Abdel, Habr, Dany, Taher, Ali
Published in European journal of haematology (01.06.2009)
Published in European journal of haematology (01.06.2009)
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Journal Article
Deferasirox and deferiprone remove cardiac iron in the iron-overloaded gerbil
Wood, John C., Otto-Duessel, Maya, Gonzalez, Ignacio, Aguilar, Michelle I., Shimada, Hiro, Nick, Hanspeter, Nelson, Marvin, Moats, Rex
Published in Translational research : the journal of laboratory and clinical medicine (01.11.2006)
Published in Translational research : the journal of laboratory and clinical medicine (01.11.2006)
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Journal Article
Comparison of Two Animal Models for Evaluation of Defersirox Iron Chelation
Otto-Duessel, Maya, Brewer, Casey, Hyderi, Aleya, Lykkesfeldt, Jens, Nielson, Peter, Nick, Hanspeter, Wood, John C
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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