Search Results - "NICHOLSON, Neville H" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB2 agonists for the treatment of inflammatory pain

Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB2 agonists for the treatment of inflammatory pain

by GLEAVE, Robert J, BESWICK, Paul J, ROOMANS, Susan, SLINGSBY, Brian P, SWARBRICK, Martin E, BROWN, Andrew J, GIBLIN, Gerard M. P, GOLDSMITH, Paul, HASLAM, Carl P, MITCHELL, William L, NICHOLSON, Neville H, PAGE, Lee W, PATEL, Sadhana
Published in Bioorganic & medicinal chemistry letters (15.01.2010)

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2-Amino-5-aryl-pyridines as selective CB2 agonists: Synthesis and investigation of structure-activity relationships

2-Amino-5-aryl-pyridines as selective CB2 agonists: Synthesis and investigation of structure-activity relationships

by GLEAVE, Robert J, BESWICK, Paul J, SWARBRICK, Martin E, BROWN, Andrew J, GIBLIN, Gerard M. P, HASLAM, Carl P, LIVERMORE, David, MOSES, Andrew, NICHOLSON, Neville H, PAGE, Lee W, SLINGSBY, Brian
Published in Bioorganic & medicinal chemistry letters (01.12.2009)

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The Discovery of a Selective, Small Molecule Agonist for the Mas-Related Gene X1 Receptor

The Discovery of a Selective, Small Molecule Agonist for the Mas-Related Gene X1 Receptor

by Wroblowski, Berthold, Wigglesworth, Mark J, Szekeres, Philip G, Smith, Graham D, Rahman, Shahzad S, Nicholson, Neville H, Muir, Alison I, Hall, Adrian, Heer, Jag P, Garland, Stephen L, Coates, William J
Published in Journal of medicinal chemistry (12.02.2009)

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Cycloadditions of Cephalosporins. A Comprehensive Study of the Reaction of Cephalosporin Triflates with Olefins, Acetylenes, and Dienes To Form [2 + 2] and [4 + 2] Adducts

Cycloadditions of Cephalosporins. A Comprehensive Study of the Reaction of Cephalosporin Triflates with Olefins, Acetylenes, and Dienes To Form [2 + 2] and [4 + 2] Adducts

by Elliott, Richard L, Nicholson, Neville H, Peaker, Fiona E, Takle, Andrew K, Richardson, Christine M, Tyler, John W, White, Janet, Pearson, Michael J, Eggleston, Drake S, Haltiwanger, R. Curtis
Published in Journal of organic chemistry (25.07.1997)

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Cycloadditions of cephalosporins. The formation of [4+2] adducts with 5-membered heterocycles

Cycloadditions of cephalosporins. The formation of [4+2] adducts with 5-membered heterocycles

by Elliott, Richard L, Nicholson, Neville H, Peaker, Fiona E, Takle, Andrew K, Tyler, John W, White, Janet
Published in Journal of organic chemistry (01.04.1994)

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Novel C-2 Substituted Carbapenem Derivatives: Part II. Synthesis and Structure-activity Relationships of Isoxazolin-2-yl, Isoxazolidin-2-yl and 2-Pyrazolin-2-yl Carbapenems Generated Using 1, 3-Dipolar Cycloaddition Chemistry

Novel C-2 Substituted Carbapenem Derivatives: Part II. Synthesis and Structure-activity Relationships of Isoxazolin-2-yl, Isoxazolidin-2-yl and 2-Pyrazolin-2-yl Carbapenems Generated Using 1, 3-Dipolar Cycloaddition Chemistry

by BURTON, GEORGE, CLARKE, GRAHAM J., DOUGLAS, JAMES D., EGLINGTON, A. JOHN, FRYDRYCH, COLIN H., MINKS, JEREMY D., HIRD, NICHOLAS W., HUNT, ERIC, MOSS, STEPHEN F., NAYLOR, ANTOINETTE, NICHOLSON, NEVILLE H., PEARSON, MICHAEL J.
Published in Journal of antibiotics (01.12.1996)

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Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB sub(2) agonists for the treatment of inflammatory pain

Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB sub(2) agonists for the treatment of inflammatory pain

by Gleave, Robert J, Beswick, Paul J, Brown, Andrew J, Giblin, Gerard MP, Goldsmith, Paul, Haslam, Carl P, Mitchell, William L, Nicholson, Neville H, Page, Lee W, Patel, Sadhana, Roomans, Susan, Slingsby, Brian P, Swarbrick, Martin E
Published in Bioorganic & medicinal chemistry letters (15.01.2010)

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Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB 2 agonists for the treatment of inflammatory pain

Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB 2 agonists for the treatment of inflammatory pain

by Gleave, Robert J., Beswick, Paul J., Brown, Andrew J., Giblin, Gerard M.P., Goldsmith, Paul, Haslam, Carl P., Mitchell, William L., Nicholson, Neville H., Page, Lee W., Patel, Sadhana, Roomans, Susan, Slingsby, Brian P., Swarbrick, Martin E.
Published in Bioorganic & medicinal chemistry letters (2010)

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Studies on the biosynthesis of clavulanic acid. Part 5. Absolute stereochemistry of proclavaminic acid, the monocyclic biosynthetic precursor of clavulanic acid

Studies on the biosynthesis of clavulanic acid. Part 5. Absolute stereochemistry of proclavaminic acid, the monocyclic biosynthetic precursor of clavulanic acid

by Baggaley, Keith H., Elson, Stephen W., Nicholson, Neville H., Sime, John T.
Published in Journal of the Chemical Society, Perkin Transactions 1 (1990)

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Studies on the biosynthesis of clavulanic acid. Part 4. Synthetic routes to the monocyclic β-lactam precursor, proclavaminic acid

Studies on the biosynthesis of clavulanic acid. Part 4. Synthetic routes to the monocyclic β-lactam precursor, proclavaminic acid

by Baggaley, Keith H., Elson, Stephen W., Nicholson, Neville H., Sime, John T.
Published in J. Chem. Soc., Perkin Trans. 1 (1990)

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2-Amino-5-aryl-pyridines as selective CB 2 agonists: Synthesis and investigation of structure–activity relationships

2-Amino-5-aryl-pyridines as selective CB 2 agonists: Synthesis and investigation of structure–activity relationships

by Gleave, Robert J., Beswick, Paul J., Brown, Andrew J., Giblin, Gerard M.P., Haslam, Carl P., Livermore, David, Moses, Andrew, Nicholson, Neville H., Page, Lee W., Slingsby, Brian, Swarbrick, Martin E.
Published in Bioorganic & medicinal chemistry letters (2009)

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Product-substrate engineering by bacteria: Studies on clavaminate synthase, a trifunctional dioxygenase

Product-substrate engineering by bacteria: Studies on clavaminate synthase, a trifunctional dioxygenase

by Lloyd, Matthew D., Merritt, Kirsten D., Lee, Victor, Sewell, Timothy J., Wha-Son, Byeng, Baldwin, Jack E., Schofield, Christopher J., Elson, Steve W., Baggaley, Keith H., Nicholson, Neville H.
Published in Tetrahedron (13.08.1999)

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The identification of three new biosynthetic intermediates and one further biosynthetic enzyme in the clavulanic acid pathway

The identification of three new biosynthetic intermediates and one further biosynthetic enzyme in the clavulanic acid pathway

by ELSON, S. W, BAGGALEY, K. H, DAVISON, M, FULSTON, M, NICHOLSON, N. H, RISBRIDGER, G. D, TYLER, J. W
Published in Journal of the Chemical Society. Chemical communications (1993)

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EVIDENCE THAT THE IMMEDIATE BIOSYNTHETIC PRECURSOR OF CLAVULANIC ACID IS ITS N-ALDEHYDE ANALOG

EVIDENCE THAT THE IMMEDIATE BIOSYNTHETIC PRECURSOR OF CLAVULANIC ACID IS ITS N-ALDEHYDE ANALOG

by NICHOLSON, NH, BAGGALEY, KH, CASSELS, R, DAVISON, M, ELSON, SW, FULSTON, M, TYLER, JW, WORONIECKI
Published in Journal of the Chemical Society. Chemical communications (1994)

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Evidence that arginine is a later metabolic intermediate than ornithine in the biosynthesis of clavulanic acid by Streptomyces clavuligerus

Evidence that arginine is a later metabolic intermediate than ornithine in the biosynthesis of clavulanic acid by Streptomyces clavuligerus

by VALENTINE, B. P, BAILEY, C. R, DOHERTY, A, MORRIS, J, ELSON, S. W, BAGGALEY, K. H, NICHOLSON, N. H
Published in Journal of the Chemical Society. Chemical communications (1993)

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A SUBSTRATE-ANALOG STUDY ON CLAVAMINIC ACID SYNTHASE - POSSIBLE CLUES TO THE BIOSYNTHETIC ORIGIN OF PROCLAVAMIC ACID

A SUBSTRATE-ANALOG STUDY ON CLAVAMINIC ACID SYNTHASE - POSSIBLE CLUES TO THE BIOSYNTHETIC ORIGIN OF PROCLAVAMIC ACID

by BALDWIN, JE, LLOYD, MD, WHASON, B, SCHOFIELD, CJ, ELSON, SW, BAGGALEY, KH, NICHOLSON, NH
Published in Journal of the Chemical Society. Chemical communications (1993)

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Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB(2) agonists for the treatment of inflammatory pain

Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB(2) agonists for the treatment of inflammatory pain

by Gleave, Robert J, Beswick, Paul J, Brown, Andrew J, Giblin, Gerard M P, Goldsmith, Paul, Haslam, Carl P, Mitchell, William L, Nicholson, Neville H, Page, Lee W, Patel, Sadhana, Roomans, Susan, Slingsby, Brian P, Swarbrick, Martin E
Published in Bioorganic & medicinal chemistry letters (15.01.2010)

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Isolation of two novel intracellular β-lactams and a novel dioxygenase cyclising enzyme from Streptomyces clavuligerus

Isolation of two novel intracellular β-lactams and a novel dioxygenase cyclising enzyme from Streptomyces clavuligerus

by ELSON, S. W, BAGGALEY, K. H, GILLETT, J, HOLLAND, S, NICHOLSON, N. H, SIME, J. T, WORONIECKI, S. R
Published in Journal of the Chemical Society. Chemical communications (1987)

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Two novel arginine derivatives from a mutant of Streptomyces clavuligerus

Two novel arginine derivatives from a mutant of Streptomyces clavuligerus

by ELSON, S. W, BAGGALEY, K. H, FULSTON, M, NICHOLSON, N. H, TYLER, J. W, EDWARDS, J, HOLMS, H, HAMILTON, I, MOUSDALE, D. M
Published in Journal of the Chemical Society. Chemical communications (1993)

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ABSOLUTE STEREOCHEMISTRY OF PROCLAVAMINIC ACID, THE MONOCYCLIC BIOSYNTHETIC PRECURSOR OF CLAVULANIC ACID

ABSOLUTE STEREOCHEMISTRY OF PROCLAVAMINIC ACID, THE MONOCYCLIC BIOSYNTHETIC PRECURSOR OF CLAVULANIC ACID

by BAGGALEY, KH, NICHOLSON, NH, SIME, JT
Published in Journal of the Chemical Society. Chemical communications (1988)

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