Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin
Graham, Rona K., Deng, Yu, Slow, Elizabeth J., Haigh, Brendan, Bissada, Nagat, Lu, Ge, Pearson, Jacqueline, Shehadeh, Jacqueline, Bertram, Lisa, Murphy, Zoe, Warby, Simon C., Doty, Crystal N., Roy, Sophie, Wellington, Cheryl L., Leavitt, Blair R., Raymond, Lynn A., Nicholson, Donald W., Hayden, Michael R.
Published in Cell (16.06.2006)
Published in Cell (16.06.2006)
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Journal Article
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
Green, Douglas R, Nicholson, Donald W, Saleh, Maya, Mathison, John C, Wolinski, Melissa K, Bensinger, Steve J, Fitzgerald, Patrick, Droin, Nathalie, Ulevitch, Richard J
Published in Nature (20.04.2006)
Published in Nature (20.04.2006)
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The Long Form of FLIP Is an Activator of Caspase-8 at the Fas Death-inducing Signaling Complex
Micheau, Olivier, Thome, Margot, Schneider, Pascal, Holler, Nils, Tschopp, Jürg, Nicholson, Donald W, Briand, Christophe, Grütter, Markus G
Published in The Journal of biological chemistry (22.11.2002)
Published in The Journal of biological chemistry (22.11.2002)
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Lung eQTLs to help reveal the molecular underpinnings of asthma
Hao, Ke, Bossé, Yohan, Nickle, David C, Paré, Peter D, Postma, Dirkje S, Laviolette, Michel, Sandford, Andrew, Hackett, Tillie L, Daley, Denise, Hogg, James C, Elliott, W Mark, Couture, Christian, Lamontagne, Maxime, Brandsma, Corry-Anke, van den Berge, Maarten, Koppelman, Gerard, Reicin, Alise S, Nicholson, Donald W, Malkov, Vladislav, Derry, Jonathan M, Suver, Christine, Tsou, Jeffrey A, Kulkarni, Amit, Zhang, Chunsheng, Vessey, Rupert, Opiteck, Greg J, Curtis, Sean P, Timens, Wim, Sin, Don D
Published in PLoS genetics (01.11.2012)
Published in PLoS genetics (01.11.2012)
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Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection
Yeretssian, Garabet, Doiron, Karine, Shao, Wei, Leavitt, Blair R, Hayden, Michael R, Nicholson, Donald W, Saleh, Maya
Published in Proceedings of the National Academy of Sciences - PNAS (02.06.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (02.06.2009)
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Journal Article
Caspase Cleavage of Mutant Huntingtin Precedes Neurodegeneration in Huntington's Disease
Wellington, Cheryl L, Ellerby, Lisa M, Gutekunst, Claire-Anne, Rogers, Danny, Warby, Simon, Graham, Rona K, Loubser, Odell, van Raamsdonk, Jeremy, Singaraja, Roshni, Yang, Yu-Zhou, Gafni, Juliette, Bredesen, Dale, Hersch, Steven M, Leavitt, Blair R, Roy, Sophie, Nicholson, Donald W, Hayden, Michael R
Published in The Journal of neuroscience (15.09.2002)
Published in The Journal of neuroscience (15.09.2002)
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Journal Article
Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi
Nicholson, Donald W, Gervais, François G, Singaraja, Roshni, Xanthoudakis, Steven, Gutekunst, Claire-Anne, Leavitt, Blair R, Metzler, Martina, Hackam, Abigail S, Tam, John, Vaillancourt, John P, Houtzager, Vicky, Rasper, Dita M, Roy, Sophie, Hayden, Michael R
Published in Nature cell biology (01.02.2002)
Published in Nature cell biology (01.02.2002)
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Journal Article
Caspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis
Mancini, Marie, Machamer, Carolyn E., Roy, Sophie, Nicholson, Donald W., Thornberry, Nancy A., Casciola-Rosen, Livia A., Rosen, Antony
Published in The Journal of cell biology (01.05.2000)
Published in The Journal of cell biology (01.05.2000)
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Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation
Flavell, Richard A, Zheng, Timothy S, Hunot, Stéphane, Kuida, Keisuke, Momoi, Takashi, Srinivasan, Anu, Nicholson, Donald W, Lazebnik, Yuri
Published in Nature medicine (01.11.2000)
Published in Nature medicine (01.11.2000)
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Journal Article
Confinement of caspase-12 proteolytic activity to autoprocessing
Roy, Sophie, Sharom, Jeffrey R, Houde, Caroline, Loisel, Thomas P, Vaillancourt, John P, Shao, Wei, Saleh, Maya, Nicholson, Donald W
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2008)
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MerCASBA: an updated and refined database of caspase substrates
Fridman, Arthur, Pak, Irene, Butts, Brent D., Hoek, Maarten, Nicholson, Donald W., Mehmet, Huseyin
Published in Apoptosis (London) (01.03.2013)
Published in Apoptosis (London) (01.03.2013)
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Journal Article
Bax-Dependent Caspase-3 Activation Is a Key Determinant in p53-Induced Apoptosis in Neurons
Cregan, Sean P, MacLaurin, Jason G, Craig, Constance G, Robertson, George S, Nicholson, Donald W, Park, David S, Slack, Ruth S
Published in The Journal of neuroscience (15.09.1999)
Published in The Journal of neuroscience (15.09.1999)
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Journal Article
The Caspase-3 Precursor Has a Cytosolic and Mitochondrial Distribution: Implications for Apoptotic Signaling
Mancini, Marie, Nicholson, Donald W., Roy, Sophie, Thornberry, Nancy A., Peterson, Erin P., Casciola-Rosen, Livia A., Rosen, Antony
Published in The Journal of cell biology (23.03.1998)
Published in The Journal of cell biology (23.03.1998)
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Selective, Reversible Caspase-3 Inhibitor Is Neuroprotective and Reveals Distinct Pathways of Cell Death after Neonatal Hypoxic-ischemic Brain Injury
Han, Byung Hee, Xu, Daigen, Choi, Junjeong, Han, Yongxin, Xanthoudakis, Steven, Roy, Sophie, Tam, John, Vaillancourt, John, Colucci, John, Siman, Robert, Giroux, Andre, Robertson, George S., Zamboni, Robert, Nicholson, Donald W., Holtzman, David M.
Published in The Journal of biological chemistry (16.08.2002)
Published in The Journal of biological chemistry (16.08.2002)
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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
Nicholson, Donald W, Ali, Ambereen, Thornberry, Nancy A, Vaillancourt, John P, Ding, Connie K, Gallant, Michel, Gareau, Yves, Griffin, Patrick R, Labelle, Marc, Lazebnik, Yuri A, Munday, Neil A, Raju, Sayyaparaju M, Smulson, Mark E, Yamin, Ting-Ting, Yu, Violeta L, Miller, Douglas K
Published in Nature (London) (06.07.1995)
Published in Nature (London) (06.07.1995)
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Neuroprotection by the Inhibition of Apoptosis
Robertson, George S., Crocker, Stephen J., Nicholson, Donald W., Schulz, Jörg B.
Published in Brain pathology (Zurich, Switzerland) (01.04.2000)
Published in Brain pathology (Zurich, Switzerland) (01.04.2000)
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Journal Article
The Neuronal Apoptosis Inhibitory Protein Is a Direct Inhibitor of Caspases 3 and 7
Maier, Johannes K. X, Lahoua, Zahia, Gendron, Nathalie H, Fetni, Raouf, Johnston, Anne, Davoodi, Jamshid, Rasper, Dita, Roy, Sophie, Slack, Ruth S, Nicholson, Donald W, MacKenzie, Alex E
Published in The Journal of neuroscience (15.03.2002)
Published in The Journal of neuroscience (15.03.2002)
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Journal Article
Caspases 3 and 9 Send a Pro-Apoptotic Signal from Synapse to Cell Body in Olfactory Receptor Neurons
Cowan, Catherine M, Thai, Jimmy, Krajewski, Stanislaw, Reed, John C, Nicholson, Donald W, Kaufmann, Scott H, Roskams, A. Jane
Published in The Journal of neuroscience (15.09.2001)
Published in The Journal of neuroscience (15.09.2001)
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