mRNA levels can be reduced by antisense oligonucleotides via no-go decay pathway
Liang, Xue-Hai, Nichols, Joshua G, Hsu, Chih-Wei, Vickers, Timothy A, Crooke, Stanley T
Published in Nucleic acids research (26.07.2019)
Published in Nucleic acids research (26.07.2019)
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Journal Article
Golgi-endosome transport mediated by M6PR facilitates release of antisense oligonucleotides from endosomes
Liang, Xue-hai, Sun, Hong, Hsu, Chih-Wei, Nichols, Joshua G, Vickers, Timothy A, De Hoyos, Cheryl L, Crooke, Stanley T
Published in Nucleic acids research (20.02.2020)
Published in Nucleic acids research (20.02.2020)
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Journal Article
Perinuclear positioning of endosomes can affect PS-ASO activities
Liang, Xue-hai, Nichols, Joshua G, Tejera, Dario, Crooke, Stanley T
Published in Nucleic acids research (16.12.2021)
Published in Nucleic acids research (16.12.2021)
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Journal Article
COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways
Liang, Xue-hai, Sun, Hong, Nichols, Joshua G, Allen, Nickolas, Wang, Shiyu, Vickers, Timothy A, Shen, Wen, Hsu, Chih-Wei, Crooke, Stanley T
Published in Nucleic acids research (02.11.2018)
Published in Nucleic acids research (02.11.2018)
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Journal Article
Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins
Migawa, Michael T, Shen, Wen, Wan, W Brad, Vasquez, Guillermo, Oestergaard, Michael E, Low, Audrey, De Hoyos, Cheryl L, Gupta, Ruchi, Murray, Susan, Tanowitz, Michael, Bell, Melanie, Nichols, Joshua G, Gaus, Hans, Liang, Xue-Hai, Swayze, Eric E, Crooke, Stanley T, Seth, Punit P
Published in Nucleic acids research (20.06.2019)
Published in Nucleic acids research (20.06.2019)
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Journal Article
Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activity
Liang, Xue-Hai, Shen, Wen, Sun, Hong, Kinberger, Garth A, Prakash, Thazha P, Nichols, Joshua G, Crooke, Stanley T
Published in Nucleic acids research (05.05.2016)
Published in Nucleic acids research (05.05.2016)
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Journal Article
Translation can affect the antisense activity of RNase H1-dependent oligonucleotides targeting mRNAs
Liang, Xue-Hai, Nichols, Joshua G, Sun, Hong, Crooke, Stanley T
Published in Nucleic acids research (09.01.2018)
Published in Nucleic acids research (09.01.2018)
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Journal Article
Hsc70 Facilitates Mannose-6-Phosphate Receptor-Mediated Intracellular Trafficking and Enhances Endosomal Release of Phosphorothioate-Modified Antisense Oligonucleotides
Liang, Xue-Hai, Nichols, Joshua G, Hsu, Chih-Wei, Crooke, Stanley T
Published in Nucleic acid therapeutics (01.08.2021)
Published in Nucleic acid therapeutics (01.08.2021)
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Journal Article
Democratic Multiplicity: Perceiving, Enacting, and Integrating Democratic Diversity
Tully, James, Cherry, Keith, Forman, Fonna, Morefield, Jeanne, Nichols, Joshua, Ouziel, Pablo, Owen, David, Schmidtke, Oliver
Year of Publication 21.07.2022
Year of Publication 21.07.2022
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Use of a conformational switching aptamer for rapid and specific ex vivo identification of central nervous system lymphoma in a xenograft model
Georges, Joseph F, Liu, Xiaowei, Eschbacher, Jennifer, Nichols, Joshua, Mooney, Michael A, Joy, Anna, Spetzler, Robert F, Feuerstein, Burt G, Preul, Mark C, Anderson, Trent, Yan, Hao, Nakaji, Peter
Published in PloS one (15.04.2015)
Published in PloS one (15.04.2015)
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Journal Article
PCR-based approach to distinguish group A human rotavirus genotype 1 vs. genotype 2 genes
McKell, Allison O., Nichols, Joshua C., McDonald, Sarah M.
Published in Journal of virological methods (01.12.2013)
Published in Journal of virological methods (01.12.2013)
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Journal Article