Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics
Chen, Jennifer CJ, King, Oliver D, Zhang, Yuanfan, Clayton, Nicholas P, Spencer, Carrie, Wentworth, Bruce M, Emerson, Charles P, Wagner, Kathryn R
Published in Molecular therapy (01.08.2016)
Published in Molecular therapy (01.08.2016)
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Journal Article
Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease
Clayton, Nicholas P, Nelson, Carol A, Weeden, Timothy, Taylor, Kristin M, Moreland, Rodney J, Scheule, Ronald K, Phillips, Lucy, Leger, Andrew J, Cheng, Seng H, Wentworth, Bruce M
Published in Molecular therapy. Nucleic acids (01.10.2014)
Published in Molecular therapy. Nucleic acids (01.10.2014)
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Journal Article
Dimorphic effects of transforming growth factor-β signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome
Cook, Jason R, Clayton, Nicholas P, Carta, Luca, Galatioto, Josephine, Chiu, Emily, Smaldone, Silvia, Nelson, Carol A, Cheng, Seng H, Wentworth, Bruce M, Ramirez, Francesco
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2015)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2015)
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Journal Article
Sargramostim (rhu GM-CSF) Improves Survival of Non-Human Primates with Severe Bone Marrow Suppression after Acute, High-Dose, Whole-Body Irradiation
Clayton, Nicholas P, Khan-Malek, Richard C, Dangler, Charles A, Zhang, Donghui, Ascah, Alexis, Gains, Malcolm, Gardner, Brent, Mockbee, Colleen, Keutzer, Joan M, McManus, John, Authier, Simon
Published in Radiation research (01.02.2021)
Published in Radiation research (01.02.2021)
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Journal Article
An integrative systems approach identifies novel candidates in Marfan syndrome‐related pathophysiology
Bhushan, Raghu, Altinbas, Lukas, Jäger, Marten, Zaradzki, Marcin, Lehmann, Daniel, Timmermann, Bernd, Clayton, Nicholas P., Zhu, Yunxiang, Kallenbach, Klaus, Kararigas, Georgios, Robinson, Peter N.
Published in Journal of cellular and molecular medicine (01.04.2019)
Published in Journal of cellular and molecular medicine (01.04.2019)
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Journal Article
Fibrillin‐1 Regulates Skeletal Stem Cell Differentiation by Modulating TGFβ Activity Within the Marrow Niche
Smaldone, Silvia, Clayton, Nicholas P, del Solar, Maria, Pascual, Gemma, Cheng, Seng H, Wentworth, Bruce M, Schaffler, Mitchell B, Ramirez, Francesco
Published in Journal of bone and mineral research (01.01.2016)
Published in Journal of bone and mineral research (01.01.2016)
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Journal Article
In Vitro and In Vivo Characterization of Tebipenem (TBP), an Orally Active Carbapenem, against Biothreat Pathogens
Clayton, Nicholas P, Jain, Akash, Halasohoris, Stephanie A, Pysz, Lisa M, Lembirik, Sanae, Zumbrun, Steven D, Kane, Christopher D, Hackett, Michael J, Pfefferle, Denise, Smiley, M Autumn, Anderson, Michael S, Heine, Henry, Meister, Gabriel T, Pucci, Michael J
Published in Antimicrobial agents and chemotherapy (01.05.2021)
Published in Antimicrobial agents and chemotherapy (01.05.2021)
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Journal Article
Inhibiting TGF-β Activity Improves Respiratory Function in mdx Mice
Nelson, Carol A, Hunter, R. Bridge, Quigley, Lindsay A, Girgenrath, Stefan, Weber, William D, McCullough, Jennifer A, Dinardo, Carol J, Keefe, Kelly A, Ceci, Lorena, Clayton, Nicholas P, McVie-Wylie, Alison, Cheng, Seng H, Leonard, John P, Wentworth, Bruce M
Published in The American journal of pathology (01.06.2011)
Published in The American journal of pathology (01.06.2011)
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Journal Article
Systemic Delivery of a Peptide-Linked Morpholino Oligonucleotide Neutralizes Mutant RNA Toxicity in a Mouse Model of Myotonic Dystrophy
Leger, Andrew J., Mosquea, Leocadia M., Clayton, Nicholas P., Wu, I-Huan, Weeden, Timothy, Nelson, Carol A., Phillips, Lucy, Roberts, Errin, Piepenhagen, Peter A., Cheng, Seng H., Wentworth, Bruce M.
Published in Nucleic acid therapeutics (01.04.2013)
Published in Nucleic acid therapeutics (01.04.2013)
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Journal Article
Systemic Delivery of a Peptide-Linked Morpholino Oligonucleotide Neutralizes Mutant RNA Toxicity in a Mouse Model of Myotonic Dystrophy
Leger, Andrew J., Mosquea, Leocadia M., Clayton, Nicholas P., Wu, I-Huan, Weeden, Timothy, Nelson, Carol A., Phillips, Lucy, Roberts, Errin, Piepenhagen, Peter A., Cheng, Seng H., Wentworth, Bruce M.
Published in Nucleic acid therapeutics (01.04.2013)
Published in Nucleic acid therapeutics (01.04.2013)
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Journal Article
MULTIPLE OLIGONUCLEOTIDE MOIETIES ON PEPTIDE CARRIER
CAROL A NELSON, TIMOTHY E WEEDEN, BRUCE M WENTWORTH, ANDREW LEGER, NICHOLAS P CLAYTON
Year of Publication 22.04.2021
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Year of Publication 22.04.2021
Patent
Sargramostim Accelerates Leukocyte Recovery and Improves Mortality Rate at Day 60 in a Non-Human Primate Model of Hematopoietic Acute Radiation Syndrome When Administered 48 h after Total Body Irradiation
Clayton, Nicholas P., Charpentier, Eric J.J., LaCasse, Emily R., Khan-Malek, Richard C., Keutzer, Joan M.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Fibrillin-1 Regulates Skeletal Stem Cell Differentiation by Modulating TGF[beta] Activity Within the Marrow Niche
Smaldone, Silvia, Clayton, Nicholas P, del Solar, Maria, Pascual, Gemma, Cheng, Seng H, Wentworth, Bruce M, Schaffler, Mitchell B, Ramirez, Francesco
Published in Journal of bone and mineral research (01.01.2016)
Published in Journal of bone and mineral research (01.01.2016)
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Journal Article
Dimorphic effects of TGFβ signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome
Cook, Jason R., Clayton, Nicholas P., Carta, Luca, Galatioto, Josephine, Chiu, Emily, Smaldone, Silvia, Nelson, Carol A., Cheng, Seng H., Wentworth, Bruce M., Ramirez, Francesco
Published in Arteriosclerosis, thrombosis, and vascular biology (22.01.2015)
Published in Arteriosclerosis, thrombosis, and vascular biology (22.01.2015)
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Journal Article
Antisense oligonucleotide-mediated suppression of muscle glycogen synthase 1 synthesis as an approach for substrate reduction therapy of Pompe disease
Clayton, Nicholas P., Nelson, Carol A., Weeden, Timothy, Taylor, Kristin M., Moreland, Rodney J., Scheule, Ronald K., Leger, Andrew J., Phillips, Lucy, Cheng, Seng H., Wentworth, Bruce M.
Published in Molecular genetics and metabolism (01.02.2015)
Published in Molecular genetics and metabolism (01.02.2015)
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Journal Article
MULTIPLE OLIGONUCLEOTIDE MOIETIES ON PEPTIDE CARRIER
LEGER, ANDREW, CLAYTON, NICHOLAS P, NELSON, CAROL A, WEEDEN, TIMOTHY E, WENTWORTH, BRUCE M
Year of Publication 26.09.2023
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Year of Publication 26.09.2023
Patent
MULTIPLE OLIGONUCLEOTIDE MOIETIES ON PEPTIDE CARRIER
WEEDEN, Timothy E, CLAYTON, Nicholas P, LEGER, Andrew, NELSON, Carol A, WENTWORTH, Bruce M
Year of Publication 19.10.2022
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Year of Publication 19.10.2022
Patent
Multiple oligonucleotide moieties on peptide carrier
Wentworth, Bruce M, Nelson, Carol A, Clayton, Nicholas P, Weeden, Timothy E, Leger, Andrew
Year of Publication 31.08.2021
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Year of Publication 31.08.2021
Patent