Inhibition of transforming growth factor beta signaling reduces pancreatic adenocarcinoma growth and invasiveness
Gaspar, Nicholas J, Li, Lingyun, Kapoun, Ann M, Medicherla, Satyanarayana, Reddy, Mamatha, Li, Georgia, O'Young, Gilbert, Quon, Diana, Henson, Margaret, Damm, Deborah L, Muiru, Gladys T, Murphy, Alison, Higgins, Linda S, Chakravarty, Sarvajit, Wong, Darren H
Published in Molecular pharmacology (01.07.2007)
Published in Molecular pharmacology (01.07.2007)
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Journal Article
Antitumor Activity of TGF-β Inhibitor is Dependent on the Microenvironment
MEDICHERLA, Satyanarayana, LINGYUN LI, WONG, Darren H, HIGGINS, Linda S, JING YING MA, KAPOUN, Ann M, GASPAR, Nicholas J, LIU, Yu-Wang, MANGADU, Ruban, O'YOUNG, Gilbert, PROTTER, Andrew A, SCHREINER, George F
Published in Anticancer research (01.11.2007)
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Published in Anticancer research (01.11.2007)
Journal Article
Transforming Growth Factor-β Receptor Type 1 (TGFβRI) Kinase Activity but Not p38 Activation Is Required for TGFβRI-Induced Myofibroblast Differentiation and Profibrotic Gene Expression
Kapoun, Ann M., Gaspar, Nicholas J., Wang, Ying, Damm, Debby, Liu, Yu-Wang, O'Young, Gilbert, Quon, Diana, Lam, Andrew, Munson, Kimberly, Tran, Thomas-Toan, Ma, Jing Ying, Murphy, Alison, Dugar, Sundeep, Chakravarty, Sarvajit, Protter, Andrew A., Wen, Fu-Qiang, Liu, Xiangde, Rennard, Stephen I., Higgins, Linda Slanec
Published in Molecular pharmacology (01.08.2006)
Published in Molecular pharmacology (01.08.2006)
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Journal Article
Activation of Key Profibrotic Mechanisms in Transgenic Fibroblasts Expressing Kinase-deficient Type II Transforming Growth Factor-β Receptor (TβRIIΔk)
Denton, Christopher P., Lindahl, Gisela E., Khan, Korsa, Shiwen, Xu, Ong, Voon H., Gaspar, Nicholas J., Lazaridis, Konstantinos, Edwards, Dylan R., Leask, Andrew, Eastwood, Mark, Leoni, Patricia, Renzoni, Elisabetta A., Bou Gharios, George, Abraham, David J., Black, Carol M.
Published in The Journal of biological chemistry (22.04.2005)
Published in The Journal of biological chemistry (22.04.2005)
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Journal Article
Inhibition of Transforming Growth Factor β Signaling Reduces Pancreatic Adenocarcinoma Growth and Invasiveness
Nicholas J. Gaspar, Lingyun Li, Ann M. Kapoun, Satyanarayana Medicherla, Mamatha Reddy, Georgia Li, Gilbert O'Young, Diana Quon, Margaret Henson, Deborah L. Damm, Gladys T. Muiru, Alison Murphy, Linda S. Higgins, Sarvajit Chakravarty, Darren H. Wong
Published in Molecular pharmacology (01.07.2007)
Published in Molecular pharmacology (01.07.2007)
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Journal Article
Antitumor Activity of TGF-β, Inhibitor is Dependent on the Microenvironment
SATYANARAYANA MEDICHERLA, LINGYUN LI, JING YING MA, ANN M. KAPOUN, NICHOLAS J. GASPAR, YU-WANG LIU, RUBAN MANGADU, GILBERT O'YOUNG, ANDREW A. PROTTER, GEORGE F. SCHREINER, DARREN H. WONG, LINDA S. HIGGINS
Published in Anticancer research (01.11.2007)
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Published in Anticancer research (01.11.2007)
Journal Article
Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression
Kapoun, Ann M, Gaspar, Nicholas J, Wang, Ying, Damm, Debby, Liu, Yu-Wang, O'young, Gilbert, Quon, Diana, Lam, Andrew, Munson, Kimberly, Tran, Thomas-Toan, Ma, Jing Ying, Murphy, Alison, Dugar, Sundeep, Chakravarty, Sarvajit, Protter, Andrew A, Wen, Fu-Qiang, Liu, Xiangde, Rennard, Stephen I, Higgins, Linda Slanec
Published in Molecular pharmacology (01.08.2006)
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Published in Molecular pharmacology (01.08.2006)
Journal Article
Transforming Growth Factor-β Receptor Type 1 (TGFβRI) Kinase Activity but Not p38 Activation Is Required for TGFβRI-Induced Myofibroblast Differentiation and Profibrotic Gene Expression
Ann M. Kapoun, Nicholas J. Gaspar, Ying Wang, Debby Damm, Yu-Wang Liu, Gilbert O'Young, Diana Quon, Andrew Lam, Kimberly Munson, Thomas-Toan Tran, Jing Ying Ma, Alison Murphy, Sundeep Dugar, Sarvajit Chakravarty, Andrew A. Protter, Fu-Qiang Wen, Xiangde Liu, Stephen I. Rennard, Linda Slanec Higgins
Published in Molecular pharmacology (01.08.2006)
Published in Molecular pharmacology (01.08.2006)
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Journal Article
Activation of key profibrotic mechanisms in transgenic fibroblasts expressing kinase-deficient type II Transforming growth factor-{beta} receptor (T{beta}RII{delta}k)
Denton, Christopher P, Lindahl, Gisela E, Khan, Korsa, Shiwen, Xu, Ong, Voon H, Gaspar, Nicholas J, Lazaridis, Konstantinos, Edwards, Dylan R, Leask, Andrew, Eastwood, Mark, Leoni, Patricia, Renzoni, Elisabetta A, Bou Gharios, George, Abraham, David J, Black, Carol M
Published in The Journal of biological chemistry (22.04.2005)
Get full text
Published in The Journal of biological chemistry (22.04.2005)
Journal Article
Activation of Key Profibrotic Mechanisms in Transgenic Fibroblasts Expressing Kinase-deficient Type II Transforming Growth Factor-β Receptor (TβRIIÎk)
Christopher P. Denton, Gisela E. Lindahl, Korsa Khan, Xu Shiwen, Voon H. Ong, Nicholas J. Gaspar, Konstantinos Lazaridis, Dylan R. Edwards, Andrew Leask, Mark Eastwood, Patricia Leoni, Elisabetta A. Renzoni, George Bou Gharios, David J. Abraham, Carol M. Black
Published in The Journal of biological chemistry (22.04.2005)
Published in The Journal of biological chemistry (22.04.2005)
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Journal Article