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Published in Journal of medicinal chemistry (22.10.2020)
Published in Journal of medicinal chemistry (22.10.2020)
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Rapid Multistep Synthesis of 1,2,4-Oxadiazoles in a Single Continuous Microreactor Sequence
Grant, Daniel, Dahl, Russell, Cosford, Nicholas D. P
Published in Journal of organic chemistry (19.09.2008)
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Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins
Finlay, Darren, Teriete, Peter, Vamos, Mitchell, Cosford, Nicholas D P, Vuori, Kristiina
Published in F1000 research (2017)
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Design and Synthesis of Systemically Active Metabotropic Glutamate Subtype‑2 and -3 (mGlu2/3) Receptor Positive Allosteric Modulators (PAMs): Pharmacological Characterization and Assessment in a Rat Model of Cocaine Dependence
Dhanya, Raveendra-Panickar, Sheffler, Douglas J, Dahl, Russell, Davis, Melinda, Lee, Pooi San, Yang, Li, Nickols, Hilary Highfield, Cho, Hyekyung P, Smith, Layton H, D’Souza, Manoranjan S, Conn, P. Jeffrey, Der-Avakian, Andre, Markou, Athina, Cosford, Nicholas D. P
Published in Journal of medicinal chemistry (22.05.2014)
Published in Journal of medicinal chemistry (22.05.2014)
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Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis
Welsh, Kate, Milutinovic, Snezana, Ardecky, Robert J, Gonzalez-Lopez, Marcos, Ganji, Santhi Reddy, Teriete, Peter, Finlay, Darren, Riedl, Stefan, Matsuzawa, Shu-Ichi, Pinilla, Clemencia, Houghten, Richard, Vuori, Kristiina, Reed, John C, Cosford, Nicholas D P
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Published in PloS one (12.09.2016)
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Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7‑((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4‑[11C]methoxyphenyl) quinoline-2-carboxamide, for Imaging of Metabotropic Glutamate Receptor 2
Zhang, Xiaofei, Kumata, Katsushi, Yamasaki, Tomoteru, Cheng, Ran, Hatori, Akiko, Ma, Longle, Zhang, Yiding, Xie, Lin, Wang, Lu, Kang, Hye Jin, Sheffler, Douglas J, Cosford, Nicholas D. P, Zhang, Ming-Rong, Liang, Steven H
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Published in ACS chemical neuroscience (20.09.2017)
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Potent, Selective, and Orally Available Benzoisothiazolone Phosphomannose Isomerase Inhibitors as Probes for Congenital Disorder of Glycosylation Ia
Dahl, Russell, Bravo, Yalda, Sharma, Vandana, Ichikawa, Mie, Dhanya, Raveendra-Panickar, Hedrick, Michael, Brown, Brock, Rascon, Justin, Vicchiarelli, Michael, Mangravita-Novo, Arianna, Yang, Li, Stonich, Derek, Su, Ying, Smith, Layton H, Sergienko, Eduard, Freeze, Hudson H, Cosford, Nicholas D. P
Published in Journal of medicinal chemistry (26.05.2011)
Published in Journal of medicinal chemistry (26.05.2011)
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Design and synthesis of pyrazole derivatives as potent and selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP)
Sidique, Shyama, Ardecky, Robert, Su, Ying, Narisawa, Sonoko, Brown, Brock, Millán, José Luis, Sergienko, Eduard, Cosford, Nicholas D.P.
Published in Bioorganic & medicinal chemistry letters (01.01.2009)
Published in Bioorganic & medicinal chemistry letters (01.01.2009)
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Orally Active Metabotropic Glutamate Subtype 2 Receptor Positive Allosteric Modulators: Structure–Activity Relationships and Assessment in a Rat Model of Nicotine Dependence
Sidique, Shyama, Dhanya, Raveendra-Panickar, Sheffler, Douglas J, Nickols, Hilary Highfield, Yang, Li, Dahl, Russell, Mangravita-Novo, Arianna, Smith, Layton H, D’Souza, Manoranjan S, Semenova, Svetlana, Conn, P. Jeffrey, Markou, Athina, Cosford, Nicholas D. P
Published in Journal of medicinal chemistry (26.11.2012)
Published in Journal of medicinal chemistry (26.11.2012)
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Structure–activity relationship and improved hydrolytic stability of pyrazole derivatives that are allosteric inhibitors of West Nile Virus NS2B-NS3 proteinase
Sidique, Shyama, Shiryaev, Sergey A., Ratnikov, Boris I., Herath, Ananda, Su, Ying, Strongin, Alex Y., Cosford, Nicholas D.P.
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer
Ren, Huiyu, Bakas, Nicole A, Vamos, Mitchell, Chaikuad, Apirat, Limpert, Allison S, Wimer, Carina D, Brun, Sonja N, Lambert, Lester J, Tautz, Lutz, Celeridad, Maria, Sheffler, Douglas J, Knapp, Stefan, Shaw, Reuben J, Cosford, Nicholas D. P
Published in Journal of medicinal chemistry (10.12.2020)
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Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia
Bata, Nicole, Chaikuad, Apirat, Bakas, Nicole A, Limpert, Allison S, Lambert, Lester J, Sheffler, Douglas J, Berger, Lena M, Liu, Guoxiong, Yuan, Cunxiang, Wang, Li, Peng, Yi, Dong, Jing, Celeridad, Maria, Layng, Fabiana, Knapp, Stefan, Cosford, Nicholas D. P
Published in Journal of medicinal chemistry (27.01.2022)
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Perturbation of the c‑Myc–Max Protein–Protein Interaction via Synthetic α‑Helix Mimetics
Jung, Kwan-Young, Wang, Huabo, Teriete, Peter, Yap, Jeremy L, Chen, Lijia, Lanning, Maryanna E, Hu, Angela, Lambert, Lester J, Holien, Toril, Sundan, Anders, Cosford, Nicholas D. P, Prochownik, Edward V, Fletcher, Steven
Published in Journal of medicinal chemistry (09.04.2015)
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Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP
González-Lόpez, Marcos, Welsh, Kate, Finlay, Darren, Ardecky, Robert J., Ganji, Santhi Reddy, Su, Ying, yuan, Hongbin, Teriete, Peter, Mace, Peter D., Riedl, Stefan J., Vuori, Kristiina, Reed, John C., Cosford, Nicholas D.P.
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
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Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors
Noberini, Roberta, Koolpe, Mitchell, Peddibhotla, Satyamaheshwar, Dahl, Russell, Su, Ying, Cosford, Nicholas D.P., Roth, Gregory P., Pasquale, Elena B.
Published in The Journal of biological chemistry (24.10.2008)
Published in The Journal of biological chemistry (24.10.2008)
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