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Glanville, Jacob, Zhai, Wenwu, Berka, Jan, Telman, Dilduz, Huerta, Gabriella, Mehta, Gautam R, Ni, Irene, Mei, Li, Sundar, Purnima D, Day, Giles M.R, Cox, David, Rajpal, Arvind, Pons, Jaume
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Published in Proceedings of the National Academy of Sciences - PNAS (01.12.2009)
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Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2012)
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Published in Nature communications (18.11.2016)
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Campos Carrascosa, Lucia, van Beek, Adriaan A, de Ruiter, Valeska, Doukas, Michail, Wei, Jie, Fisher, Timothy S, Ching, Keith, Yang, Wenjing, van Loon, Karlijn, Boor, Patrick P C, Rakké, Yannick S, Noordam, Lisanne, Doornebosch, Pascal, Grünhagen, Dirk, Verhoef, Kees, Polak, Wojciech G, IJzermans, Jan N M, Ni, Irene, Yeung, Yik Andy, Salek-Ardakani, Shahram, Sprengers, Dave, Kwekkeboom, Jaap
Published in Journal for immunotherapy of cancer (01.09.2020)
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Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts
Sarup, Jay, Jin, Pei, Turin, Lisa, Bai, Xiaomei, Beryt, Malgorzata, Brdlik, Cathleen, Higaki, Jeffrey N, Jorgensen, Brett, Lau, Francis W, Lindley, Peter, Liu, Jim, Ni, Irene, Rozzelle, James, Kumari, Rajendra, Watson, Susan A, Zhang, Juan, Shepard, H Michael
Published in Molecular cancer therapeutics (01.10.2008)
Published in Molecular cancer therapeutics (01.10.2008)
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An Optimized Full-Length FLT3/CD3 Bispecific Antibody Demonstrates Potent Anti-leukemia Activity and Reversible Hematological Toxicity
Yeung, Yik Andy, Krishnamoorthy, Veena, Dettling, Danielle, Sommer, Cesar, Poulsen, Kris, Ni, Irene, Pham, Amber, Chen, Wei, Liao-Chan, Sindy, Lindquist, Kevin, Chin, S. Michael, Chunyk, Allison Given, Hu, Wenyue, Sasu, Barbra, Chaparro-Riggers, Javier, Djuretic, Ivana
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Published in Molecular therapy (04.03.2020)
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GS-005 - Selective activation of the IL-2 pathway in CD8+ T cells drives antiviral activity to Hepatitis B Virus (HBV)
Andreata, Francesco, Moynihan, Kelly, Di Lucia, Pietro, Peppas, Danielle, Ni, Irene, Nguyen, Henri, Perucchini, Chiara, Chin, Mike, Bono, Elisa, Giustini, Leonardo, Bessette, Paul, Yeung, Andy, Gibbs, Craig, Djuretic, Ivana, Iannacone, Matteo
Published in Journal of hepatology (01.06.2023)
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Selective activation of the IL-2 pathway in CD8+ T cells drives antiviral activity to Hepatitis B Virus (HBV)
Andreata, Francesco, Moynihan, Kelly, Di Lucia, Pietro, Peppas, Danielle, Ni, Irene, Nguyen, Henri, Perucchini, Chiara, Chin, Mike, Bono, Elisa, Giustini, Leonardo, Bessette, Paul, Yeung, Andy, Gibbs, Craig, Djuretic, Ivana, Iannacone, Matteo
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
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CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus
Andreata, Francesco, Moynihan, Kelly D, Fumagalli, Valeria, Di Lucia, Pietro, Pappas, Danielle C, Kawashima, Keigo, Ni, Irene, Bessette, Paul H, Perucchini, Chiara, Bono, Elisa, Giustini, Leonardo, Nguyen, Henry C, Chin, S Michael, Yeung, Yik Andy, Gibbs, Craig S, Djuretic, Ivana, Iannacone, Matteo
Published in Science translational medicine (10.01.2024)
Published in Science translational medicine (10.01.2024)
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IL2 Targeted to CD8+ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity
Moynihan, Kelly D, Kumar, Manu P, Sultan, Hussein, Pappas, Danielle C, Park, Terrence, Chin, S Michael, Bessette, Paul, Lan, Ruth Y, Nguyen, Henry C, Mathewson, Nathan D, Ni, Irene, Chen, Wei, Lee, Yonghee, Liao-Chan, Sindy, Chen, Jessie, Schumacher, Ton N M, Schreiber, Robert D, Yeung, Yik A, Djuretic, Ivana M
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Published in Cancer discovery (01.07.2024)
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An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity
Xu, Yuanming, Carrascosa, Lucia Campos, Yeung, Yik Andy, Chu, Matthew Ling-Hon, Yang, Wenjing, Djuretic, Ivana, Pappas, Danielle C, Zeytounian, John, Ge, Zhouhong, de Ruiter, Valeska, Starbeck-Miller, Gabriel R, Patterson, James, Rigas, Diamanda, Chen, Shih-Hsun, Kraynov, Eugenia, Boor, Patrick P, Noordam, Lisanne, Doukas, Michael, Tsao, Dave, Ijzermans, Jan N, Guo, Jie, Grünhagen, Dirk J, Erdmann, Joris, Verheij, Joanne, van Royen, Martin E, Doornebosch, Pascal G, Feldman, Renny, Park, Terrence, Mahmoudi, Salah, Dorywalska, Magdalena, Ni, Irene, Chin, Sherman M, Mistry, Tina, Mosyak, Lidia, Lin, Laura, Ching, Keith A, Lindquist, Kevin C, Ji, Changhua, Londono, Luz Marina, Kuang, Bing, Rickert, Robert, Kwekkeboom, Jaap, Sprengers, Dave, Huang, Tzu-Hsuan, Chaparro-Riggers, Javier
Published in Cancer immunology research (01.10.2021)
Published in Cancer immunology research (01.10.2021)
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Synthetic Antibodies Designed on Natural Sequence Landscapes
Zhai, Wenwu, Glanville, Jacob, Fuhrmann, Markus, Mei, Li, Ni, Irene, Sundar, Purnima D., Van Blarcom, Thomas, Abdiche, Yasmina, Lindquist, Kevin, Strohner, Ralf, Telman, Dilduz, Cappuccilli, Guido, Finlay, William J.J., Van den Brulle, Jan, Cox, David R., Pons, Jaume, Rajpal, Arvind
Published in Journal of molecular biology (09.09.2011)
Published in Journal of molecular biology (09.09.2011)
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Abstract 2882: Selective activation of CD8+ T cells by a CD8-targeted IL-21 results in enhanced anti-tumor efficacy and safety
Greer, Renee, Liu, David, Nguyen, Henry, Lan, Ruth, Prior, Wei Wei, Sukthankar, Meghana, Mesko, Paul, Ni, irene, Chin, Mike, Moynihan, Kelly, Schumacher, Ton, Djuretic, Ivana, Yeung, Andy
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 3518: AB248 is a CD8+ T cell selective IL-2 designed for superior safety and anti-tumor efficacy
Moynihan, Kelly D., Pappas, Danielle, Park, Terrence, Chen, Wei, Ni, Irene, Bessette, Paul, Nguyen, Henry, Liu, David, Chin, Mike, Lan, Ruth, Arvey, Aaron, Schumacher, Ton N., Yeung, Yik Andy, Djuretic, Ivana
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Blockade of CD127 Exerts a Dichotomous Clinical Effect in Marmoset Experimental Autoimmune Encephalomyelitis
Dunham, Jordon, Lee, Li-Fen, van Driel, Nikki, Laman, Jon D., Ni, Irene, Zhai, Wenwu, Tu, Guang-Huan, Lin, John C., Bauer, Jan, ‘t Hart, Bert A., Kap, Yolanda S.
Published in Journal of neuroimmune pharmacology (01.03.2016)
Published in Journal of neuroimmune pharmacology (01.03.2016)
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Correction: Anti-IL-7 receptor-α reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function
Lee, Li-Fen, Logronio, Kathryn, Tu, Guang Huan, Zhai, Wenwu, Ni, Irene, Mei, Li, Dilley, Jeanette, Yu, Jessica, Rajpal, Arvind, Brown, Colleen, Appah, Charles, Chin, Sherman Michael, Han, Bora, Affolter, Timothy, Lin, John C.
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2012)
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Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2012)
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