Multi‐omics profiling of CHO parental hosts reveals cell line‐specific variations in bioprocessing traits
Lakshmanan, Meiyappan, Kok, Yee Jiun, Lee, Alison P., Kyriakopoulos, Sarantos, Lim, Hsueh Lee, Teo, Gavin, Poh, Swan Li, Tang, Wen Qin, Hong, Jongkwang, Tan, Andy Hee‐Meng, Bi, Xuezhi, Ho, Ying Swan, Zhang, Peiqing, Ng, Say Kong, Lee, Dong‐Yup
Published in Biotechnology and bioengineering (01.09.2019)
Published in Biotechnology and bioengineering (01.09.2019)
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Gold Nanoparticle‐based “Mix and Measure” Fluorimetric Assays to Quantify Antibody Titer
Sutarlie, Laura, Siak‐Wie Ow, Dave, Kong Ng, Say, Yang, Yuansheng, Su, Xiaodi
Published in Chemistry, an Asian journal (18.10.2021)
Published in Chemistry, an Asian journal (18.10.2021)
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Applications and analysis of hydrolysates in animal cell culture
Ho, Yin Ying, Lu, Hao Kim, Lim, Zhi Feng Sherman, Lim, Hao Wei, Ho, Ying Swan, Ng, Say Kong
Published in Bioresources and bioprocessing (28.09.2021)
Published in Bioresources and bioprocessing (28.09.2021)
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Application of maltose as energy source in protein-free CHO-K1 culture to improve the production of recombinant monoclonal antibody
Leong, Dawn Sow Zong, Teo, Brian Kah Hui, Tan, Janice Gek Ling, Kamari, Hayati, Yang, Yuan Sheng, Zhang, Peiqing, Ng, Say Kong
Published in Scientific reports (06.03.2018)
Published in Scientific reports (06.03.2018)
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Advances in Mammalian cell line development technologies for recombinant protein production
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Book Review
HEK293 Cell Line as a Platform to Produce Recombinant Proteins and Viral Vectors
Tan, Evan, Chin, Cara Sze Hui, Lim, Zhi Feng Sherman, Ng, Say Kong
Published in Frontiers in bioengineering and biotechnology (13.12.2021)
Published in Frontiers in bioengineering and biotechnology (13.12.2021)
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Harnessing the potential of machine learning for advancing "Quality by Design" in biomanufacturing
Walsh, Ian, Myint, Matthew, Nguyen-Khuong, Terry, Ho, Ying Swan, Ng, Say Kong, Lakshmanan, Meiyappan
Published in mAbs (31.12.2022)
Published in mAbs (31.12.2022)
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Utility of Ion-Mobility Spectrometry for Deducing Branching of Multiply Charged Glycans and Glycopeptides in a High-Throughput Positive ion LC-FLR-IMS-MS Workflow
Pallister, Edward G, Choo, Matthew S. F, Walsh, Ian, Tai, Jien Nee, Tay, Shi Jie, Yang, Yuan Sheng, Ng, Say Kong, Rudd, Pauline M, Flitsch, Sabine L, Nguyen-Khuong, Terry
Published in Analytical chemistry (Washington) (01.12.2020)
Published in Analytical chemistry (Washington) (01.12.2020)
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A human expression system based on HEK293 for the stable production of recombinant erythropoietin
Chin, Christine Lin, Goh, Justin Bryan, Srinivasan, Harini, Liu, Kaiwen Ivy, Gowher, Ali, Shanmugam, Raghuvaran, Lim, Hsueh Lee, Choo, Matthew, Tang, Wen Qin, Tan, Andy Hee-Meng, Nguyen-Khuong, Terry, Tan, Meng How, Ng, Say Kong
Published in Scientific reports (14.11.2019)
Published in Scientific reports (14.11.2019)
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Multi‐omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer, and product quality
Lee, Alison P., Kok, Yee Jiun, Lakshmanan, Meiyappan, Leong, Dawn, Zheng, Lu, Lim, Hsueh Lee, Chen, Shuwen, Mak, Shi Ya, Ang, Kok Siong, Templeton, Neil, Salim, Taha, Wei, Xiaona, Gifford, Eric, Tan, Andy Hee‐Meng, Bi, Xuezhi, Ng, Say Kong, Lee, Dong‐Yup, Ling, Wai Lam W., Ho, Ying Swan
Published in Biotechnology and bioengineering (01.11.2021)
Published in Biotechnology and bioengineering (01.11.2021)
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Exploiting the Disialyl Galactose Activity of α2,6-Sialyltransferase from Photobacterium damselae To Generate a Highly Sialylated Recombinant α‑1-Antitrypsin
Pallister, Edward G, Choo, Matthew S. F, Tai, Jien-Nee, Leong, Dawn S. Z, Tang, Wen-Qin, Ng, Say-Kong, Huang, Kun, Marchesi, Andrea, Both, Peter, Gray, Christopher, Rudd, Pauline M, Flitsch, Sabine L, Nguyen-Khuong, Terry
Published in Biochemistry (Easton) (01.09.2020)
Published in Biochemistry (Easton) (01.09.2020)
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DOK3 is required for IFN-β production by enabling TRAF3/TBK1 complex formation and IRF3 activation
Kim, Susana Soo-Yeon, Lee, Koon-Guan, Chin, Ching-Siang, Ng, Say-Kong, Pereira, Natasha Ann, Xu, Shengli, Lam, Kong-Peng
Published in The Journal of immunology (1950) (15.07.2014)
Published in The Journal of immunology (1950) (15.07.2014)
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Antibody glycan quality predicted from CHO cell culture media markers and machine learning
Lakshmanan, Meiyappan, Chia, Sean, Pang, Kuin Tian, Sim, Lyn Chiin, Teo, Gavin, Mak, Shi Ya, Chen, Shuwen, Lim, Hsueh Lee, Lee, Alison P., Bin Mahfut, Farouq, Ng, Say Kong, Yang, Yuansheng, Soh, Annie, Tan, Andy Hee-Meng, Choo, Andre, Ho, Ying Swan, Nguyen-Khuong, Terry, Walsh, Ian
Published in Computational and structural biotechnology journal (01.12.2024)
Published in Computational and structural biotechnology journal (01.12.2024)
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Investigation on environmental factors contributing to bispecific antibody stability and the reversal of self-associated aggregates
Ingavat, Nattha, Dzulkiflie, Nuruljannah, Liew, Jia Min, Wang, Xinhui, Leong, Eunice, Loh, Han Ping, Ng, Say Kong, Yang, Yuansheng, Zhang, Wei
Published in Bioresources and bioprocessing (23.08.2024)
Published in Bioresources and bioprocessing (23.08.2024)
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Heat shock protein 27 overexpression in CHO cells modulates apoptosis pathways and delays activation of caspases to improve recombinant monoclonal antibody titre in fed-batch bioreactors
Tan, Janice G L, Lee, Yih Yean, Wang, Tianhua, Yap, Miranda G S, Tan, Tin Wee, Ng, Say Kong
Published in Biotechnology journal (01.05.2015)
Published in Biotechnology journal (01.05.2015)
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