SARS-CoV-2 Mpro inhibitors and activity-based probes for patient-sample imaging
Rut, Wioletta, Groborz, Katarzyna, Zhang, Linlin, Sun, Xinyuanyuan, Zmudzinski, Mikolaj, Pawlik, Bartlomiej, Wang, Xinyu, Jochmans, Dirk, Neyts, Johan, Młynarski, Wojciech, Hilgenfeld, Rolf, Drag, Marcin
Published in Nature chemical biology (01.02.2021)
Published in Nature chemical biology (01.02.2021)
Get full text
Journal Article
Update on hepatitis E virology: Implications for clinical practice
Debing, Yannick, Moradpour, Darius, Neyts, Johan, Gouttenoire, Jérôme
Published in Journal of hepatology (01.07.2016)
Published in Journal of hepatology (01.07.2016)
Get full text
Journal Article
The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern
Abdelnabi, Rana, Foo, Caroline S., Jochmans, Dirk, Vangeel, Laura, De Jonghe, Steven, Augustijns, Patrick, Mols, Raf, Weynand, Birgit, Wattanakul, Thanaporn, Hoglund, Richard M., Tarning, Joel, Mowbray, Charles E., Sjö, Peter, Escudié, Fanny, Scandale, Ivan, Chatelain, Eric, Neyts, Johan
Published in Nature communications (15.02.2022)
Published in Nature communications (15.02.2022)
Get full text
Journal Article
Clinical practices underlie COVID-19 patient respiratory microbiome composition and its interactions with the host
Lloréns-Rico, Verónica, Gregory, Ann C., Van Weyenbergh, Johan, Jansen, Sander, Van Buyten, Tina, Qian, Junbin, Braz, Marcos, Menezes, Soraya Maria, Van Mol, Pierre, Vanderbeke, Lore, Dooms, Christophe, Gunst, Jan, Hermans, Greet, Meersseman, Philippe, Wauters, Els, Neyts, Johan, Lambrechts, Diether, Wauters, Joost, Raes, Jeroen
Published in Nature communications (29.10.2021)
Published in Nature communications (29.10.2021)
Get full text
Journal Article
Antiviral drug discovery against arthritogenic alphaviruses: Tools and molecular targets
Abdelnabi, Rana, Jacobs, Sofie, Delang, Leen, Neyts, Johan
Published in Biochemical pharmacology (01.04.2020)
Published in Biochemical pharmacology (01.04.2020)
Get full text
Journal Article
Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture
DE WILDE, Adriaan H, JOCHMANS, Dirk, POSTHUMA, Clara C, ZEVENHOVEN-DOBBE, Jessika C, VAN NIEUWKOOP, Stefan, BESTEBROER, Theo M, VAN DEN HOOGEN, Bernadette G, NEYTS, Johan, SNIJDER, Eric J
Published in Antimicrobial agents and chemotherapy (01.08.2014)
Published in Antimicrobial agents and chemotherapy (01.08.2014)
Get full text
Journal Article
The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model
Zmurko, Joanna, Marques, Rafael E, Schols, Dominique, Verbeken, Erik, Kaptein, Suzanne J F, Neyts, Johan
Published in PLoS neglected tropical diseases (10.05.2016)
Published in PLoS neglected tropical diseases (10.05.2016)
Get full text
Journal Article
A robust human norovirus replication model in zebrafish larvae
Van Dycke, Jana, Ny, Annelii, Conceição-Neto, Nádia, Maes, Jan, Hosmillo, Myra, Cuvry, Arno, Goodfellow, Ian, Nogueira, Tatiane C, Verbeken, Erik, Matthijnssens, Jelle, de Witte, Peter, Neyts, Johan, Rocha-Pereira, Joana
Published in PLoS pathogens (19.09.2019)
Published in PLoS pathogens (19.09.2019)
Get full text
Journal Article
ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies
Low, Jun Siong, Jerak, Josipa, Tortorici, M Alejandra, McCallum, Matthew, Pinto, Dora, Cassotta, Antonino, Foglierini, Mathilde, Mele, Federico, Abdelnabi, Rana, Weynand, Birgit, Noack, Julia, Montiel-Ruiz, Martin, Bianchi, Siro, Benigni, Fabio, Sprugasci, Nicole, Joshi, Anshu, Bowen, John E, Stewart, Cameron, Rexhepaj, Megi, Walls, Alexandra C, Jarrossay, David, Morone, Diego, Paparoditis, Philipp, Garzoni, Christian, Ferrari, Paolo, Ceschi, Alessandro, Neyts, Johan, Purcell, Lisa A, Snell, Gyorgy, Corti, Davide, Lanzavecchia, Antonio, Veesler, David, Sallusto, Federica
Published in Science (American Association for the Advancement of Science) (12.08.2022)
Published in Science (American Association for the Advancement of Science) (12.08.2022)
Get full text
Journal Article
Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV‑2
Dai, Wenhao, Jochmans, Dirk, Xie, Hang, Yang, Hang, Li, Jian, Su, Haixia, Chang, Di, Wang, Jiang, Peng, Jingjing, Zhu, Lili, Nian, Yong, Hilgenfeld, Rolf, Jiang, Hualiang, Chen, Kaixian, Zhang, Leike, Xu, Yechun, Neyts, Johan, Liu, Hong
Published in Journal of medicinal chemistry (24.02.2022)
Published in Journal of medicinal chemistry (24.02.2022)
Get full text
Journal Article
A prospect on the use of antiviral drugs to control local outbreaks of COVID-19
Torneri, Andrea, Libin, Pieter, Vanderlocht, Joris, Vandamme, Anne-Mieke, Neyts, Johan, Hens, Niel
Published in BMC medicine (25.06.2020)
Published in BMC medicine (25.06.2020)
Get full text
Journal Article
Nirmatrelvir-resistant SARS-CoV-2 is efficiently transmitted in female Syrian hamsters and retains partial susceptibility to treatment
Abdelnabi, Rana, Jochmans, Dirk, Donckers, Kim, Trüeb, Bettina, Ebert, Nadine, Weynand, Birgit, Thiel, Volker, Neyts, Johan
Published in Nature communications (14.04.2023)
Published in Nature communications (14.04.2023)
Get full text
Journal Article
Reverse engineering synthetic antiviral amyloids
Michiels, Emiel, Roose, Kenny, Gallardo, Rodrigo, Khodaparast, Ladan, Khodaparast, Laleh, van der Kant, Rob, Siemons, Maxime, Houben, Bert, Ramakers, Meine, Wilkinson, Hannah, Guerreiro, Patricia, Louros, Nikolaos, Kaptein, Suzanne J. F., Ibañez, Lorena Itatí, Smet, Anouk, Baatsen, Pieter, Liu, Shu, Vorberg, Ina, Bormans, Guy, Neyts, Johan, Saelens, Xavier, Rousseau, Frederic, Schymkowitz, Joost
Published in Nature communications (05.06.2020)
Published in Nature communications (05.06.2020)
Get full text
Journal Article
CCL20, a direct-acting pro-angiogenic chemokine induced by hepatitis C virus (HCV): Potential role in HCV-related liver cancer
Benkheil, Mohammed, Van Haele, Matthias, Roskams, Tania, Laporte, Manon, Noppen, Sam, Abbasi, Kayvan, Delang, Leen, Neyts, Johan, Liekens, Sandra
Published in Experimental cell research (15.11.2018)
Published in Experimental cell research (15.11.2018)
Get full text
Journal Article
Infection of zebrafish larvae with human norovirus and evaluation of the in vivo efficacy of small-molecule inhibitors
Van Dycke, Jana, Cuvry, Arno, Knickmann, Jan, Ny, Annelii, Rakers, Sebastian, Taube, Stefan, de Witte, Peter, Neyts, Johan, Rocha-Pereira, Joana
Published in Nature protocols (01.04.2021)
Published in Nature protocols (01.04.2021)
Get full text
Journal Article