Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer’s Disease
Budd Haeberlein, Samantha, Aisen, P.S., Barkhof, F., Chalkias, S., Chen, T., Cohen, S., Dent, G., Hansson, O., Harrison, K., von Hehn, C., Iwatsubo, T., Mallinckrodt, C., Mummery, C.J., Muralidharan, K.K., Nestorov, I., Nisenbaum, L., Rajagovindan, R., Skordos, L., Tian, Y., van Dyck, C.H., Vellas, B., Wu, S., Zhu, Y., Sandrock, A.
Published in The journal of prevention of Alzheimer's disease (2022)
Published in The journal of prevention of Alzheimer's disease (2022)
Get full text
Journal Article
Recombinant factor VIII Fc fusion protein: extended‐interval dosing maintains low bleeding rates and correlates with von Willebrand factor levels
Shapiro, A. D., Ragni, M. V., Kulkarni, R., Oldenberg, J., Srivastava, A., Quon, D. V., Pasi, K. J., Hanabusa, H., Pabinger, I., Mahlangu, J., Fogarty, P., Lillicrap, D., Kulke, S., Potts, J., Neelakantan, S., Nestorov, I., Li, S., Dumont, J. A., Jiang, H., Brennan, A., Pierce, G. F.
Published in Journal of thrombosis and haemostasis (01.11.2014)
Published in Journal of thrombosis and haemostasis (01.11.2014)
Get full text
Journal Article
An exploratory dose-escalating study investigating the safety, tolerability, pharmacokinetics and pharmacodynamics of intravenous atacicept in patients with systemic lupus erythematosus
Pena-Rossi, C, Nasonov, E, Stanislav, M, Yakusevich, V, Ershova, O, Lomareva, N, Saunders, H, Hill, J, Nestorov, I
Published in Lupus (01.05.2009)
Published in Lupus (01.05.2009)
Get full text
Journal Article
Atacicept in relapsed refractory multiple myeloma or active Waldenström's macroglobulinemia: a phase I study
ROSSI, J.-F, MOREAUX, J, KLEIN, B, HOSE, D, REQUIRAND, G, ROSE, M, ROUILLE, V, NESTOROV, I, MORDENT, G, GOLDSCHMIDT, H, YTHIER, A
Published in British journal of cancer (06.10.2009)
Published in British journal of cancer (06.10.2009)
Get full text
Journal Article
Investigating Partially Discordant Results in Phase 3 Studies of Aducanumab
Mallinckrodt, C., Tian, Y., Aisen, P. S., Barkhof, F., Cohen, S., Dent, G., Hansson, O., Harrison, K., Iwatsubo, T., Mummery, C. J., Muralidharan, K. K., Nestorov, I., Nisenbaum, L., Rajagovindan, R., von Hehn, C., van Dyck, C. H., Vellas, B., Wu, S., Zhu, Y., Sandrock, A., Chen, T., Budd Haeberlein, Samantha
Published in The journal of prevention of Alzheimer's disease (2023)
Published in The journal of prevention of Alzheimer's disease (2023)
Get full text
Journal Article
Lumping of whole-body physiologically based pharmacokinetic models
NESTOROV, I. A, AARONS, L. J, ARUNDEL, P. A, ROWLAND, M
Published in Journal of pharmacokinetics and biopharmaceutics (01.02.1998)
Published in Journal of pharmacokinetics and biopharmaceutics (01.02.1998)
Get full text
Journal Article
Quantitative structure-pharmacokinetics relationships : I. Development of a whole-body physiologically based model to characterize changes in pharmacokinetics across a homologous series of barbiturates in the rat
BLAKEY, G. E, NESTOROV, I. A, ARUNDEL, P. A, AARONS, L. J, ROWLAND, M
Published in Journal of pharmacokinetics and biopharmaceutics (01.06.1997)
Published in Journal of pharmacokinetics and biopharmaceutics (01.06.1997)
Get full text
Journal Article
Atacicept in patients with rheumatoid arthritis: Results of a multicenter, phase ib, double‐blind, placebo‐controlled, dose‐escalating, single‐ and repeated‐dose study
Tak, P. P., Thurlings, R. M., Rossier, C., Nestorov, I., Dimic, A., Mircetic, V., Rischmueller, M., Nasonov, E., Shmidt, E., Emery, P., Munafo, A.
Published in Arthritis and rheumatism (01.01.2008)
Published in Arthritis and rheumatism (01.01.2008)
Get full text
Journal Article
Modelling and simulation of variability and uncertainty in toxicokinetics and pharmacokinetics
Get full text
Journal Article
Conference Proceeding
PEGylated interferon beta-1a: meeting an unmet medical need in the treatment of relapsing multiple sclerosis
Baker, Darren P, Pepinsky, Robert Blake, Brickelmaier, Margot, Gronke, Robert S, Hu, Xiao, Olivier, Kenneth, Lerner, Michaela, Miller, Larisa, Crossman, Mary, Nestorov, Ivan, Subramanyam, Meena, Hitchman, Stacy, Glick, Gabrielle, Richman, Sandra, Liu, Shifang, Zhu, Ying, Panzara, Michael A, Davar, Gudarz
Published in Journal of interferon & cytokine research (01.10.2010)
Published in Journal of interferon & cytokine research (01.10.2010)
Get full text
Journal Article
Fuzzy Least Squares for Identification of Individual Pharmacokinetic Parameters
Seng, Kok-Yong, Nestorov, Ivan, Vicini, Paolo
Published in IEEE transactions on biomedical engineering (01.12.2009)
Published in IEEE transactions on biomedical engineering (01.12.2009)
Get full text
Journal Article