The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic
Hoffmann, Markus, Krüger, Nadine, Schulz, Sebastian, Cossmann, Anne, Rocha, Cheila, Kempf, Amy, Nehlmeier, Inga, Graichen, Luise, Moldenhauer, Anna-Sophie, Winkler, Martin S., Lier, Martin, Dopfer-Jablonka, Alexandra, Jäck, Hans-Martin, Behrens, Georg M.N., Pöhlmann, Stefan
Published in Cell (03.02.2022)
Published in Cell (03.02.2022)
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Journal Article
SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination
Hoffmann, Markus, Hofmann-Winkler, Heike, Krüger, Nadine, Kempf, Amy, Nehlmeier, Inga, Graichen, Luise, Arora, Prerna, Sidarovich, Anzhalika, Moldenhauer, Anna-Sophie, Winkler, Martin S., Schulz, Sebastian, Jäck, Hans-Martin, Stankov, Metodi V., Behrens, Georg M.N., Pöhlmann, Stefan
Published in Cell reports (Cambridge) (20.07.2021)
Published in Cell reports (Cambridge) (20.07.2021)
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Journal Article
Glycan-Gold Nanoparticles as Multifunctional Probes for Multivalent Lectin–Carbohydrate Binding: Implications for Blocking Virus Infection and Nanoparticle Assembly
Budhadev, Darshita, Poole, Emma, Nehlmeier, Inga, Liu, Yuanyuan, Hooper, James, Kalverda, Elizabeth, Akshath, Uchangi Satyaprasad, Hondow, Nicole, Turnbull, W. Bruce, Pöhlmann, Stefan, Guo, Yuan, Zhou, Dejian
Published in Journal of the American Chemical Society (21.10.2020)
Published in Journal of the American Chemical Society (21.10.2020)
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Journal Article
Cleavage and Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by Human Airway Trypsin-Like Protease
BERTRAM, Stephanie, GLOWACKA, Ilona, SOILLEUX, Elizabeth J, JAHN, Olaf, STEFFEN, Imke, PÖHLMANN, Stefan, MÜLLER, Marcel A, LAVENDER, Hayley, GNIRSS, Kerstin, NEHLMEIER, Inga, NIEMEYER, Daniela, YUXIAN HE, SIMMONS, Graham, DROSTEN, Christian
Published in Journal of Virology (01.12.2011)
Published in Journal of Virology (01.12.2011)
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Journal Article
Omicron subvariant BA.5 efficiently infects lung cells
Hoffmann, Markus, Wong, Lok-Yin Roy, Arora, Prerna, Zhang, Lu, Rocha, Cheila, Odle, Abby, Nehlmeier, Inga, Kempf, Amy, Richter, Anja, Halwe, Nico Joel, Schön, Jacob, Ulrich, Lorenz, Hoffmann, Donata, Beer, Martin, Drosten, Christian, Perlman, Stanley, Pöhlmann, Stefan
Published in Nature communications (13.06.2023)
Published in Nature communications (13.06.2023)
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Journal Article
Hemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human Airways
Laporte, Manon, Stevaert, Annelies, Raeymaekers, Valerie, Boogaerts, Talitha, Nehlmeier, Inga, Chiu, Winston, Benkheil, Mohammed, Vanaudenaerde, Bart, Pöhlmann, Stefan, Naesens, Lieve
Published in Journal of virology (12.12.2019)
Published in Journal of virology (12.12.2019)
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Journal Article
The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells
Brinkmann, Constantin, Hoffmann, Markus, Lübke, Anastasia, Nehlmeier, Inga, Krämer-Kühl, Annika, Winkler, Michael, Pöhlmann, Stefan
Published in PloS one (07.12.2017)
Published in PloS one (07.12.2017)
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Journal Article
Delta variant (B.1.617.2) sublineages do not show increased neutralization resistance
Arora, Prerna, Kempf, Amy, Nehlmeier, Inga, Graichen, Luise, Sidarovich, Anzhalika, Winkler, Martin S., Schulz, Sebastian, Jäck, Hans-Martin, Stankov, Metodi V., Behrens, Georg M. N., Pöhlmann, Stefan, Hoffmann, Markus
Published in Cellular & molecular immunology (01.11.2021)
Published in Cellular & molecular immunology (01.11.2021)
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Journal Article
TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection
Metzdorf, Kristin, Jacobsen, Henning, Greweling-Pils, Marina C, Hoffmann, Markus, Lüddecke, Tatjana, Miller, Felicitas, Melcher, Lars, Kempf, Amy M, Nehlmeier, Inga, Bruder, Dunja, Widera, Marek, Ciesek, Sandra, Pöhlmann, Stefan, Čičin-Šain, Luka
Published in Viruses (18.01.2023)
Published in Viruses (18.01.2023)
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Journal Article
Tmprss2 knock-out mice are resistant to H10 influenza A virus pathogenesis
Lambertz, Ruth L O, Gerhauser, Ingo, Nehlmeier, Inga, Leist, Sarah R, Kollmus, Heike, Pöhlmann, Stefan, Schughart, Klaus
Published in Journal of general virology (01.07.2019)
Published in Journal of general virology (01.07.2019)
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Journal Article
Humoral and Cellular Immune Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 Variants and Human Coronaviruses After Single BNT162b2 Vaccination
Stankov, Metodi V, Cossmann, Anne, Bonifacius, Agnes, Dopfer-Jablonka, Alexandra, Ramos, Gema Morillas, Gödecke, Nina, Scharff, Anna Zychlinsky, Happle, Christine, Boeck, Anna-Lena, Tran, Anh Thu, Pink, Isabell, Hoeper, Marius M, Blasczyk, Rainer, Winkler, Martin S, Nehlmeier, Inga, Kempf, Amy, Hofmann-Winkler, Heike, Hoffmann, Markus, Eiz-Vesper, Britta, Pöhlmann, Stefan, Behrens, Georg M N
Published in Clinical infectious diseases (06.12.2021)
Published in Clinical infectious diseases (06.12.2021)
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Journal Article
DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry
Zmora, Pawel, Blazejewska, Paulina, Moldenhauer, Anna-Sophie, Welsch, Kathrin, Nehlmeier, Inga, Wu, Qingyu, Schneider, Heike, Pöhlmann, Stefan, Bertram, Stephanie
Published in Journal of virology (01.10.2014)
Published in Journal of virology (01.10.2014)
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Journal Article
The spike protein of SARS-CoV-2 variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency
Arora, Prerna, Rocha, Cheila, Kempf, Amy, Nehlmeier, Inga, Graichen, Luise, Winkler, Martin S., Lier, Martin, Schulz, Sebastian, Jäck, Hans-Martin, Cossmann, Anne, Stankov, Metodi V., Behrens, Georg M. N., Pöhlmann, Stefan, Hoffmann, Markus
Published in Cellular & molecular immunology (01.12.2021)
Published in Cellular & molecular immunology (01.12.2021)
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Journal Article
Evidence for an ACE2-Independent Entry Pathway That Can Protect from Neutralization by an Antibody Used for COVID-19 Therapy
Hoffmann, Markus, Sidarovich, Anzhalika, Arora, Prerna, Krüger, Nadine, Nehlmeier, Inga, Kempf, Amy, Graichen, Luise, Winkler, Martin S, Niemeyer, Daniela, Goffinet, Christine, Drosten, Christian, Schulz, Sebastian, Jäck, Hans-Martin, Pöhlmann, Stefan
Published in mBio (28.06.2022)
Published in mBio (28.06.2022)
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Journal Article
A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry
Hoffmann, Markus, Crone, Lisa, Dietzel, Erik, Paijo, Jennifer, González-Hernández, Mariana, Nehlmeier, Inga, Kalinke, Ulrich, Becker, Stephan, Pöhlmann, Stefan
Published in Journal of virology (01.05.2017)
Published in Journal of virology (01.05.2017)
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Journal Article
The SARS-CoV-2 Delta-Omicron Recombinant Lineage (XD) Exhibits Immune-Escape Properties Similar to the Omicron (BA.1) Variant
Arora, Prerna, Zhang, Lu, Rocha, Cheila, Graichen, Luise, Nehlmeier, Inga, Kempf, Amy, Cossmann, Anne, Ramos, Gema Morillas, Baier, Eva, Tampe, Björn, Moerer, Onnen, Dickel, Steffen, Winkler, Martin S, Behrens, Georg M N, Pöhlmann, Stefan, Hoffmann, Markus
Published in International journal of molecular sciences (14.11.2022)
Published in International journal of molecular sciences (14.11.2022)
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Journal Article
SARS-CoV-2 variants C.1.2 and B.1.621 (Mu) partially evade neutralization by antibodies elicited upon infection or vaccination
Arora, Prerna, Kempf, Amy, Nehlmeier, Inga, Graichen, Luise, Winkler, Martin S., Lier, Martin, Schulz, Sebastian, Jäck, Hans-Martin, Cossmann, Anne, Stankov, Metodi V., Behrens, Georg M.N., Pöhlmann, Stefan, Hoffmann, Markus
Published in Cell Reports (03.05.2022)
Published in Cell Reports (03.05.2022)
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No evidence for increased cell entry or antibody evasion by Delta sublineage AY.4.2
Arora, Prerna, Kempf, Amy, Nehlmeier, Inga, Graichen, Luise, Winkler, Martin S., Lier, Martin, Schulz, Sebastian, Jäck, Hans-Martin, Pöhlmann, Stefan, Hoffmann, Markus
Published in Cellular & molecular immunology (01.03.2022)
Published in Cellular & molecular immunology (01.03.2022)
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Journal Article
H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice
Lambertz, Ruth Lydia Olga, Gerhauser, Ingo, Nehlmeier, Inga, Gärtner, Sabine, Winkler, Michael, Leist, Sarah Rebecca, Kollmus, Heike, Pöhlmann, Stefan, Schughart, Klaus
Published in Virology journal (22.04.2020)
Published in Virology journal (22.04.2020)
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Journal Article
Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins
Plegge, Teresa, Spiegel, Martin, Krüger, Nadine, Nehlmeier, Inga, Winkler, Michael, González Hernández, Mariana, Pöhlmann, Stefan
Published in PloS one (11.04.2019)
Published in PloS one (11.04.2019)
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