A mouse Fcγ-Fcϵ protein that inhibits mast cells through activation of FcγRIIB, SH2 domain–containing inositol phosphatase 1, and SH2 domain–containing protein tyrosine phosphatases
Mertsching, Elisabeth, PhD, Bafetti, Lisa, BS, Hess, Henry, PhD, Perper, Stuart, BS, Giza, Keith, BS, Allen, Lisa Chan, PhD, Negrou, Ella, BS, Hathaway, Karen, BS, Hopp, Jennifer, MS, Chung, Julie, BS, Perret, Daniel, MS, Shields, Michael, PhD, Saxon, Andrew, MD, Kehry, Marilyn R., PhD
Published in Journal of allergy and clinical immunology (2008)
Published in Journal of allergy and clinical immunology (2008)
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Journal Article
Discovery of structural diverse reversible BTK inhibitors utilized to develop a novel in vivo CD69 and CD86 PK/PD mouse model
Vandeveer, George H., Arduini, Robert M., Baker, Darren P., Barry, Kevin, Bohnert, Tonika, Bowden-Verhoek, Jon K., Conlon, Patrick, Cullen, Patrick F., Guan, Bing, Jenkins, Tracy J., Liao, Shu-Yu, Lin, Lin, Liu, Yu-Ting, Marcotte, Douglas, Mertsching, Elisabeth, Metrick, Claire M., Negrou, Ella, Powell, Noel, Scott, Daniel, Silvian, Laura F., Hopkins, Brian T.
Published in Bioorganic & medicinal chemistry letters (15.01.2023)
Published in Bioorganic & medicinal chemistry letters (15.01.2023)
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Journal Article
Optimization of novel reversible Bruton’s tyrosine kinase inhibitors identified using Tethering-fragment-based screens
Hopkins, Brian T., Bame, Eris, Bell, Noah, Bohnert, Tonika, Bowden-Verhoek, Jon K., Bui, Minna, Cancilla, Mark T., Conlon, Patrick, Cullen, Patrick, Erlanson, Daniel A., Fan, Junfa, Fuchs-Knotts, Tarra, Hansen, Stig, Heumann, Stacey, Jenkins, Tracy J., Marcotte, Douglas, McDowell, Bob, Mertsching, Elisabeth, Negrou, Ella, Otipoby, Kevin L., Poreci, Urjana, Romanowski, Michael J., Scott, Daniel, Silvian, Laura, Yang, Wenjin, Zhong, Min
Published in Bioorganic & medicinal chemistry (01.07.2019)
Published in Bioorganic & medicinal chemistry (01.07.2019)
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Journal Article
Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton’s tyrosine kinase inhibitors
Hopkins, Brian T., Bame, Eris, Bell, Noah, Bohnert, Tonika, Bowden-Verhoek, Jon K., Bui, Minna, Cancilla, Mark T., Conlon, Patrick, Cullen, Patrick, Erlanson, Daniel A., Fan, Junfa, Fuchs-Knotts, Tarra, Hansen, Stig, Heumann, Stacey, Jenkins, Tracy J., Gua, Chuck, Liu, Ying, Liu, YuTing, Lulla, Mukush, Marcotte, Douglas, Marx, Isaac, McDowell, Bob, Mertsching, Elisabeth, Negrou, Ella, Romanowski, Michael J., Scott, Daniel, Silvian, Laura, Yang, Wenjin, Zhong, Min
Published in Bioorganic & medicinal chemistry (15.08.2021)
Published in Bioorganic & medicinal chemistry (15.08.2021)
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Journal Article
Homeostasis and anergy of CD4 + CD25 + suppressor T cells in vivo
Negrou, Ella, Gavin, Marc A, Gallegos, Alena, Rudensky, Alexander, Clarke, Sally R
Published in Nature immunology (01.01.2002)
Published in Nature immunology (01.01.2002)
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Journal Article
Systemic administration of an Fcγ–Fcε-fusion protein in house dust mite sensitive nonhuman primates
Van Scott, Michael R, Mertsching, Elisabeth, Negrou, Ella, Miles, Jeremy, Stallings, Howard W, Graff, Candace, Kehry, Marilyn R
Published in Clinical immunology (Orlando, Fla.) (01.09.2008)
Published in Clinical immunology (Orlando, Fla.) (01.09.2008)
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Journal Article
Mechanisms of allergy and clinical immunology: A mouse Fc gamma -Fc epsilon protein that inhibits mast cells through activation of Fc gamma RIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases
Mertsching, Elisabeth, Bafetti, Lisa, Hess, Henry, Perper, Stuart, Giza, Keith, Allen, Lisa Chan, Negrou, Ella, Hathaway, Karen, Hopp, Jennifer, Chung, Julie, Perret, Daniel, Shields, Michael, Saxon, Andrew, Kehry, Marilyn R
Published in Journal of allergy and clinical immunology (01.02.2008)
Published in Journal of allergy and clinical immunology (01.02.2008)
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Journal Article
A mouse Fc[gamma]-Fc[epsilon] protein that inhibits mast cells through activation of Fc[gamma]RIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases
Mertsching, Elisabeth, Bafetti, Lisa, Hess, Henry, Perper, Stuart, Giza, Keith, Allen, Lisa Chan, Negrou, Ella, Hathaway, Karen, Hopp, Jennifer, Chung, Julie, Perret, Daniel, Shields, Michael, Saxon, Andrew, Kehry, Marilyn R
Published in Journal of allergy and clinical immunology (01.02.2008)
Published in Journal of allergy and clinical immunology (01.02.2008)
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Journal Article
A mouse Fcγ-Fc∈ protein that inhibits mast cells through activation of FcγRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases
MERTSCHING, Elisabeth, BAFETTI, Lisa, PERRET, Daniel, SHIELDS, Michael, SAXON, Andrew, KEHRY, Marilyn R, HESS, Henry, PERPER, Stuart, GIZA, Keith, CHAN ALLEN, Lisa, NEGROU, Ella, HATHAWAY, Karen, HOPP, Jennifer, CHUNG, Julie
Published in Journal of allergy and clinical immunology (2008)
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Published in Journal of allergy and clinical immunology (2008)
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Cytoskeletal disruption induces T cell apoptosis by a caspase-3 mediated mechanism
Suria, Hamza, Chau, Luan A., Negrou, Ella, Kelvin, David J., Madrenas, Joaquín
Published in Life sciences (1973) (12.11.1999)
Published in Life sciences (1973) (12.11.1999)
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Phospho-Rab antibodies, assays and methods of use thereof
Moerke, Nathan, Wang, Xiang, Dugas, Jason C, Maloney, Michael T, Huntwork-Rodriguez, Sarah, Negrou, Ella, Henry, Anastasia
Year of Publication 30.05.2023
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Year of Publication 30.05.2023
Patent
Homeostasis and anergy of [CD4.sup.+][CD25.sup.+] suppressor T cells in vivo
Gavin, Marc A, Clarke, Sally R, Negrou, Ella, Gallegos, Alena, Rudensky, Alexander
Published in Nature immunology (01.01.2002)
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Published in Nature immunology (01.01.2002)
Journal Article
Systemic administration of an Fcgamma-Fc(epsilon)-fusion protein in house dust mite sensitive nonhuman primates
Van Scott, Michael R, Mertsching, Elisabeth, Negrou, Ella, Miles, Jeremy, Stallings, 3rd, Howard W, Graff, Candace, Kehry, Marilyn R
Published in Clinical immunology (Orlando, Fla.) (01.09.2008)
Published in Clinical immunology (Orlando, Fla.) (01.09.2008)
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Journal Article
Homeostasis and anergy of CD4 super(+) CD25 super(+) suppressor T cells in vivo
Gavin, MA, Clarke, SR, Negrou, E, Gallegos, A, Rudensky, A
Published in Nature immunology (01.01.2002)
Published in Nature immunology (01.01.2002)
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Journal Article
PHOSPHO-RAB ANTIBODIES, ASSAYS AND METHODS OF USE THEREOF
Moerke, Nathan, Wang, Xiang, Dugas, Jason C, Maloney, Michael T, Huntwork-Rodriguez, Sarah, Negrou, Ella, Henry, Anastasia
Year of Publication 20.05.2021
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Year of Publication 20.05.2021
Patent
A mouse Fcgamma-Fcepsilon protein that inhibits mast cells through activation of FcgammaRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases
Mertsching, Elisabeth, Bafetti, Lisa, Hess, Henry, Perper, Stuart, Giza, Keith, Allen, Lisa Chan, Negrou, Ella, Hathaway, Karen, Hopp, Jennifer, Chung, Julie, Perret, Daniel, Shields, Michael, Saxon, Andrew, Kehry, Marilyn R
Published in Journal of allergy and clinical immunology (01.02.2008)
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Published in Journal of allergy and clinical immunology (01.02.2008)
Journal Article
PHOSPHO-RAB ANTIBODIES, ASSAYS AND METHODS OF USE THEREOF
HUNTWORK-RODRIGUEZ, Sarah, DUGAS, Jason C, MOERKE, Nathan, NEGROU, Ella, MALONEY, Michael T, HENRY, Anastasia, WANG, Xiang
Year of Publication 07.02.2019
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Year of Publication 07.02.2019
Patent
PHOSPHO-RAB ANTIBODIES, ASSAYS AND METHODS OF USE THEREOF
HUNTWORK-RODRIGUEZ, Sarah, DUGAS, Jason C, MOERKE, Nathan, NEGROU, Ella, MALONEY, Michael T, HENRY, Anastasia, WANG, Xiang
Year of Publication 20.12.2018
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Year of Publication 20.12.2018
Patent