Blocking TRPA1 in Respiratory Disorders: Does It Hold a Promise?
Mukhopadhyay, Indranil, Kulkarni, Abhay, Khairatkar-Joshi, Neelima
Published in Pharmaceuticals (05.11.2016)
Published in Pharmaceuticals (05.11.2016)
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Book Review
Transient receptor potential ankyrin 1 receptor activation in vitro and in vivo by pro-tussive agents: GRC 17536 as a promising anti-tussive therapeutic
Mukhopadhyay, Indranil, Kulkarni, Abhay, Aranake, Sarika, Karnik, Pallavi, Shetty, Mahesh, Thorat, Sandeep, Ghosh, Indraneel, Wale, Dinesh, Bhosale, Vikram, Khairatkar-Joshi, Neelima
Published in PloS one (12.05.2014)
Published in PloS one (12.05.2014)
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Journal Article
Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells
Mukhopadhyay, Indranil, Gomes, Pearl, Aranake, Sarika, Shetty, Mahesh, Karnik, Pallavi, Damle, Madhujit, Kuruganti, Shaldavya, Thorat, Sandeep, Khairatkar-Joshi, Neelima
Published in Journal of receptors and signal transduction (01.10.2011)
Published in Journal of receptors and signal transduction (01.10.2011)
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Design, Synthesis, and Pharmacological Evaluation of 5,6-Disubstituted Pyridin-2(1H)‑one Derivatives as Phosphodiesterase 10A (PDE10A) Antagonists
Lingam, V. S. Prasadarao, Dahale, Dnyaneshwar H, Rathi, Vijay E, Shingote, Yogesh B, Thakur, Rajni R, Mindhe, Ajit S, Kummari, Srinivas, Khairatkar-Joshi, Neelima, Bajpai, Malini, Shah, Daisy M, Sapalya, Ratika S, Gullapalli, Srinivas, Gupta, Praveen K, Gudi, Girish S, Jadhav, Satyawan B, Pattem, Rambabu, Thomas, Abraham
Published in Journal of medicinal chemistry (22.10.2015)
Published in Journal of medicinal chemistry (22.10.2015)
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Journal Article
Design, synthesis and pharmacological evaluation of novel polycyclic heteroarene ethers as PDE10A inhibitors: Part I
Das, Sanjib, Harde, Rajendra L., Shelke, Dnyaneshwar E., Khairatkar-Joshi, Neelima, Bajpai, Malini, Sapalya, Ratika S., Surve, Harshada V., Gudi, Girish S., Pattem, Rambabu, Behera, Dayanidhi B., Jadhav, Satyawan B., Thomas, Abraham
Published in Bioorganic & medicinal chemistry letters (01.05.2014)
Published in Bioorganic & medicinal chemistry letters (01.05.2014)
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Journal Article
FUSED PYRIMIDINEONE COMPOUNDS AS TRPV3 MODULATORS
ABRAHAM THOMAS, SACHIN SUNDARIAL CHAUDHARI, VIDYA G. KATTIGE, V.S. PRASADARAO LINGAM, NEELIMA KHAIRATKAR JOSHI
Year of Publication 18.01.2011
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Year of Publication 18.01.2011
Patent
Discovery of 5-(2-chloro-4′-(1H-imidazol-1-yl)-[1,1′-biphenyl]-4-yl)-1H-tetrazole as potent and orally efficacious S-nitrosoglutathione reductase (GSNOR) inhibitors for the potential treatment of COPD
Muthukaman, Nagarajan, Deshmukh, Sanjay, Tondlekar, Shital, Tambe, Macchindra, Pisal, Dnyandeo, Sarode, Neelam, Mhatre, Siddharth, Chakraborti, Samitabh, Shah, Daisy, Bhosale, Vikram M., Kulkarni, Abhay, Mahat, Mahamad Yunnus A., Jadhav, Satyawan B., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (15.12.2018)
Published in Bioorganic & medicinal chemistry letters (15.12.2018)
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Journal Article
Alleviating CYP and hERG liabilities by structure optimization of dihydrofuran-fused tricyclic benzo[d]imidazole series – Potent, selective and orally efficacious microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors: Part-2
Muthukaman, Nagarajan, Deshmukh, Sanjay, Tambe, Macchindra, Pisal, Dnyandeo, Tondlekar, Shital, Shaikh, Mahamadhanif, Sarode, Neelam, Kattige, Vidya G., Sawant, Pooja, Pisat, Monali, Karande, Vikas, Honnegowda, Srinivasa, Kulkarni, Abhay, Behera, Dayanidhi, Jadhav, Satyawan B., Sangana, Ramchandra R., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (15.04.2018)
Published in Bioorganic & medicinal chemistry letters (15.04.2018)
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Journal Article
Discovery of furan and dihydrofuran-fused tricyclic benzo[d]imidazole derivatives as potent and orally efficacious microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors: Part-1
Muthukaman, Nagarajan, Tambe, Macchindra, Deshmukh, Sanjay, Pisal, Dnyandeo, Tondlekar, Shital, Shaikh, Mahamadhanif, Sarode, Neelam, Kattige, Vidya G., Pisat, Monali, Sawant, Pooja, Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Behera, Dayanidhi, Jadhav, Satyawan B., Sangana, Ramchandra R., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
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Journal Article
Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E-2 synthase-1 (mPGES-1) inhibitors: SAR and in vivo efficacy in hyperalgesia pain model
Muthukaman, Nagarajan, Tambe, Macchindra, Shaikh, Mahamadhanif, Pisal, Dnyandeo, Deshmukh, Sanjay, Tondlekar, Shital, Sarode, Neelam, Narayana, Lakshminarayana, Gajera, Jitendra M., Kattige, Vidya G., Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Behera, Dayanidhi, Jadhav, Satyawan B., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
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Journal Article
Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors: SAR and in vivo efficacy in hyperalgesia pain model
Muthukaman, Nagarajan, Tambe, Macchindra, Shaikh, Mahamadhanif, Pisal, Dnyandeo, Deshmukh, Sanjay, Tondlekar, Shital, Sarode, Neelam, Narayana, Lakshminarayana, Gajera, Jitendra M., Kattige, Vidya G., Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Behera, Dayanidhi, Jadhav, Satyawan B., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
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Journal Article
Discovery of 2-(2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino [2 ',3 ':3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E-2 synthase-1 (mPGES-1) inhibitor
Muthukaman, Nagarajan, Deshmukh, Sanjay, Sarode, Neelam, Tondlekar, Shital, Tambe, Macchindra, Pisal, Dnyandeo, Shaikh, Mahamadhanif, Kattige, Vidya G., Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Jadhav, Satyawan B., Mahat, Mahamad Yunnus A., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
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Journal Article
Discovery of 2-((2-chloro-6-fluorophenyl)amino)- N -(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1 H -[1,4]dioxino[2′,3′:3,4]benzo[1,2- d ]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E 2 synthase-1 (mPGES-1) inhibitor
Muthukaman, Nagarajan, Deshmukh, Sanjay, Sarode, Neelam, Tondlekar, Shital, Tambe, Macchindra, Pisal, Dnyandeo, Shaikh, Mahamadhanif, Kattige, Vidya G., Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Jadhav, Satyawan B., Mahat, Mahamad Yunnus A., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (01.12.2016)
Published in Bioorganic & medicinal chemistry letters (01.12.2016)
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Journal Article
Synthesis and pharmacological evaluation of novel N-aryl-3,4-dihydro-1′H-spiro[chromene-2,4′-piperidine]-1′-carboxamides as TRPM8 antagonists
Chaudhari, Sachin S., Kadam, Ashok B., Khairatkar-Joshi, Neelima, Mukhopadhyay, Indranil, Karnik, Pallavi V., Raghuram, Anupindi, Rao, Shobha S., Vaiyapuri, Thamil Selvan, Wale, Dinesh P., Bhosale, Vikram M., Gudi, Girish S., Sangana, Ramchandra R., Thomas, Abraham
Published in Bioorganic & medicinal chemistry (01.11.2013)
Published in Bioorganic & medicinal chemistry (01.11.2013)
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Imidazopyridazinones as novel PDE7 inhibitors: SAR and in vivo studies in Parkinson’s disease model
Banerjee, Abhisek, Patil, Sandip, Pawar, Mahesh Y., Gullapalli, Srinivas, Gupta, Praveen K., Gandhi, Maulik N., Bhateja, Deepak K., Bajpai, Malini, Sangana, Ramachandra Rao, Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (01.10.2012)
Published in Bioorganic & medicinal chemistry letters (01.10.2012)
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Journal Article
Discovery of benzo[d]imidazo[5,1-b]thiazole as a new class of phosphodiesterase 10A inhibitors
Banerjee, Abhisek, Narayana, Lakshminarayana, Raje, Firoj A., Pisal, Dnyandeo V., Kadam, Pradip A., Gullapalli, Srinivas, Kumar, Hemant, More, Sandeep V., Bajpai, Malini, Sangana, Ramachandra Rao, Jadhav, Satyawan, Gudi, Girish S., Khairatkar-Joshi, Neelima, Merugu, Ravi R.T., Voleti, Sreedhara R., Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
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Journal Article
Discovery of 2-((2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino[2′,3′:3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor
Muthukaman, Nagarajan, Deshmukh, Sanjay, Sarode, Neelam, Tondlekar, Shital, Tambe, Macchindra, Pisal, Dnyandeo, Shaikh, Mahamadhanif, Kattige, Vidya G., Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Jadhav, Satyawan B., Mahat, Mahamad Yunnus A., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
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