Continuous Partial Oxidation of Methane to Methanol Catalyzed by Diffusion-Paired Copper Dimers in Copper-Exchanged Zeolites
Dinh, Kimberly T, Sullivan, Mark M, Narsimhan, Karthik, Serna, Pedro, Meyer, Randall J, Dincă, Mircea, Román-Leshkov, Yuriy
Published in Journal of the American Chemical Society (24.07.2019)
Published in Journal of the American Chemical Society (24.07.2019)
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Methane to Acetic Acid over Cu-Exchanged Zeolites: Mechanistic Insights from a Site-Specific Carbonylation Reaction
Narsimhan, Karthik, Michaelis, Vladimir K, Mathies, Guinevere, Gunther, William R, Griffin, Robert G, Román-Leshkov, Yuriy
Published in Journal of the American Chemical Society (11.02.2015)
Published in Journal of the American Chemical Society (11.02.2015)
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Manufacturing Process Development for Belzutifan, Part 2: A Continuous Flow Visible-Light-Induced Benzylic Bromination
Bottecchia, Cecilia, Lévesque, François, McMullen, Jonathan P, Ji, Yining, Reibarkh, Mikhail, Peng, Feng, Tan, Lushi, Spencer, Glenn, Nappi, Jarod, Lehnherr, Dan, Narsimhan, Karthik, Wismer, Michael K, Chen, Like, Lin, Yipeng, Dalby, Stephen M
Published in Organic process research & development (18.03.2022)
Published in Organic process research & development (18.03.2022)
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Benzylic Photobromination for the Synthesis of Belzutifan: Elucidation of Reaction Mechanisms Using In Situ LED-NMR
Ji, Yining, Bottecchia, Cecilia, Lévesque, François, Narsimhan, Karthik, Lehnherr, Dan, McMullen, Jonathan P, Dalby, Stephen M, Xiao, Kai-Jiong, Reibarkh, Mikhail
Published in Journal of organic chemistry (18.02.2022)
Published in Journal of organic chemistry (18.02.2022)
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Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan
Cheung‐Lee, Wai Ling, Kolev, Joshua N., McIntosh, John A., Gil, Agnieszka A., Pan, Weilan, Xiao, Li, Velásquez, Juan E., Gangam, Rekha, Winston, Matthew S., Li, Shasha, Abe, Kotoe, Alwedi, Embarek, Dance, Zachary E. X., Fan, Haiyang, Hiraga, Kaori, Kim, Jungchul, Kosjek, Birgit, Le, Diane N., Marzijarani, Nastaran Salehi, Mattern, Keith, McMullen, Jonathan P., Narsimhan, Karthik, Vikram, Ajit, Wang, Wei, Yan, Jia‐Xuan, Yang, Rong‐Sheng, Zhang, Victoria, Zhong, Wendy, DiRocco, Daniel A., Morris, William J., Murphy, Grant S., Maloney, Kevin M.
Published in Angewandte Chemie International Edition (22.03.2024)
Published in Angewandte Chemie International Edition (22.03.2024)
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Use of a Dynamic Flow Platform To Translate a Batch Immobilized Transaminase Process to a Packed Bed Reactor for the Synthesis of an Intermediate of Nemtabrutinib
Di Maso, Michael J., Kuethe, Jeffrey T., Narsimhan, Karthik, Burris, Matthew, Chung, Cheol K., DiBenedetto, Michael, Forstater, Jacob H., Grosser, Shane T., Kuhl, Nadine, Lévesque, François, Maguire, Anne, Maloney, Kevin M., McMullen, Jonathan P., Prier, Christopher K., Qi, Ji, Rivera, Nelo R., Wang, Zhixun, Wyvratt, Brian M., Zewge, Daniel
Published in Organic process research & development (17.05.2024)
Published in Organic process research & development (17.05.2024)
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Amination of a Green Solvent via Immobilized Biocatalysis for the Synthesis of Nemtabrutinib
Prier, Christopher K., Camacho Soto, Karla, Forstater, Jacob H., Kuhl, Nadine, Kuethe, Jeffrey T., Cheung-Lee, Wai Ling, Di Maso, Michael J., Eberle, Claire M., Grosser, Shane T., Ho, Hsing-I, Hoyt, Erik, Maguire, Anne, Maloney, Kevin M., Makarewicz, Amanda, McMullen, Jonathan P., Moore, Jeffrey C., Murphy, Grant S., Narsimhan, Karthik, Pan, Weilan, Rivera, Nelo R., Saha-Shah, Anumita, Thaisrivongs, David A., Verma, Deeptak, Wyatt, Adeya, Zewge, Daniel
Published in ACS catalysis (16.06.2023)
Published in ACS catalysis (16.06.2023)
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Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 2: Development of a Robust Process for Phenol Synthesis
Peng, Feng, Humphrey, Guy R, Maloney, Kevin M, Lehnherr, Dan, Weisel, Mark, Lévesque, Francois, Naber, John R, Brunskill, Andrew P. J, Larpent, Patrick, Zhang, Si-Wei, Lee, Alfred Y, Arvary, Rebecca A, Lee, Claire H, Bishara, Daniel, Narsimhan, Karthik, Sirota, Eric, Whittington, Michael
Published in Organic process research & development (20.11.2020)
Published in Organic process research & development (20.11.2020)
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Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264). Part 5: Completion of the API Free Base via a Direct Chlorosulfonylation Process
Di Maso, Michael J, Ren, Hong, Zhang, Si-Wei, Liu, Wenjun, Desmond, Richard, Alwedi, Embarek, Narsimhan, Karthik, Kalinin, Alexei, Larpent, Patrick, Lee, Alfred Y, Ren, Sumei, Maloney, Kevin M
Published in Organic process research & development (20.11.2020)
Published in Organic process research & development (20.11.2020)
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BTK 억제제 및 그의 중간체의 합성
CHEN YONGGANG, TAN LUSHI, KUETHE JEFFREY T, CORRY JAMES, XIAO KAIJIONG, KUHL NADINE, DI MASO MICHAEL J, LEVESQUE FRANCOIS, OTTE DOUGLAS, SIROTA ERIC, FORSTATER JACOB H, PRIER CHRISTOPHER K, SHEVLIN MICHAEL, WANG ZHIXUN, NARSIMHAN KARTHIK, LARSON REED, THAISRIVONGS DAVID A, TURNBULL BEN W. H, DESMOND RICHARD
Year of Publication 30.01.2024
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Year of Publication 30.01.2024
Patent
Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan
Cheung‐Lee, Wai Ling, Kolev, Joshua N., McIntosh, John A., Gil, Agnieszka A., Pan, Weilan, Xiao, Li, Velásquez, Juan E., Gangam, Rekha, Winston, Matthew S., Li, Shasha, Abe, Kotoe, Alwedi, Embarek, Dance, Zachary E. X., Fan, Haiyang, Hiraga, Kaori, Kim, Jungchul, Kosjek, Birgit, Le, Diane N., Marzijarani, Nastaran Salehi, Mattern, Keith, McMullen, Jonathan P., Narsimhan, Karthik, Vikram, Ajit, Wang, Wei, Yan, Jia‐Xuan, Yang, Rong‐Sheng, Zhang, Victoria, Zhong, Wendy, DiRocco, Daniel A., Morris, William J., Murphy, Grant S., Maloney, Kevin M.
Published in Angewandte Chemie (22.03.2024)
Published in Angewandte Chemie (22.03.2024)
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SYNTHESIS OF BTK INHIBITOR AND INTERMEDIATES THEREOF
KUHL, Nadine, TURNBULL, Ben, DI MASO, Michael, NARSIMHAN, Karthik, FORSTATER, Jacob, LARSON, Reed, SHEVLIN, Michael, XIAO, Kaijiong, CORRY, James, TAN, Lushi, WANG, Zhixun, LEVESQUE, Francois, OTTE, Douglas, CHEN, Yonggang, KUETHE, Jeffrey, SIROTA, Eric, THAISRIVONGS, David, PRIER, Christopher, DESMOND, Richard
Year of Publication 16.11.2023
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Year of Publication 16.11.2023
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SYNTHESIS OF BTK INHIBITOR AND INTERMEDIATES THEREOF
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Year of Publication 09.11.2023
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Year of Publication 09.11.2023
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SYNTHESIS OF BTK INHIBITOR AND INTERMEDIATES THEREOF
Tan, Lushi, Narsimhan, Karthik, Sirota, Eric, Corry, James, Otte, Douglas, Xiao, Kaijiong, Kuhl, Nadine, Thaisrivongs, David A, Chen, Yonggang, Larson, Reed, Kuethe, Jeffrey T, Shevlin, Michael, Forstater, Jacob H, Levesque, Francois, Prier, Christopher K, Desmond, Richard, Di Maso, Michael J, Wang, Zhixun, Turnbull, Ben W. H
Year of Publication 08.08.2024
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Year of Publication 08.08.2024
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SYNTHESIS OF BTK INHIBITOR AND INTERMEDIATES THEREOF
KUHL, Nadine, NARSIMHAN, Karthik, LARSON, Reed, TURNBULL, Ben, W. H, FORSTATER, Jacob, H, KUETHE, Jeffrey, T, SHEVLIN, Michael, XIAO, Kaijiong, DI MASO, Michael, J, CORRY, James, PRIER, Christopher, K, TAN, Lushi, WANG, Zhixun, LEVESQUE, Francois, OTTE, Douglas, CHEN, Yonggang, SIROTA, Eric, DESMOND, Richard, THAISRIVONGS, David, A
Year of Publication 10.04.2024
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Year of Publication 10.04.2024
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