CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia
Hansen, Joshua D, Correa, Matthew, Alexander, Matt, Nagy, Mark, Huang, Dehua, Sapienza, John, Lu, Gang, LeBrun, Laurie A, Cathers, Brian E, Zhang, Weihong, Tang, Yang, Ammirante, Massimo, Narla, Rama K, Piccotti, Joseph R, Pourdehnad, Michael, Lopez-Girona, Antonia
Published in Journal of medicinal chemistry (25.02.2021)
Published in Journal of medicinal chemistry (25.02.2021)
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Pomalidomide in combination with dexamethasone results in synergistic anti‐tumour responses in pre‐clinical models of lenalidomide‐resistant multiple myeloma
Rychak, Emily, Mendy, Derek, Shi, Tao, Ning, Yuhong, Leisten, Jim, Lu, Ling, Miller, Karen, Narla, Rama K., Orlowski, Robert Z., Raymon, Heather K., Bjorklund, Chad C., Thakurta, Anjan, Gandhi, Anita K., Cathers, Brian E., Chopra, Rajesh, Daniel, Thomas O., Lopez‐Girona, Antonia
Published in British journal of haematology (01.03.2016)
Published in British journal of haematology (01.03.2016)
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Journal Article
TOR TREATMENT OF PROSTATE CANCER WITH TOR KINASE INHIBITORS
HEGE KRISTEN MAE, TSUJI TOSHIYA, NARLA RAMA K, MORTENSEN DEBORAH, FULTZ KIMBERLY ELIZABETH, RAYMON HEATHER
Year of Publication 21.09.2020
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Year of Publication 21.09.2020
Patent
항증식성 화합물 및 이의 사용 방법
CARMICHAEL JAMES, ALEXANDER MATTHEW D, CARRANCIO SORAYA, CATHERS BRIAN E, CORREA MATTHEW D, WHITEFIELD BRANDON W, LOPEZ GIRONA ANTONIA, BRAY GORDON L, KERCHER TIMOTHY S, ARTMAN GERALD D. III, HANSEN JOSHUA, ZOU NANFEI, PICCOTTI JOSEPH R, NARLA RAMA K, TAVARES GRECO PAULA A, PIERCE DANIEL W, WONG LILLY L, NAGY MARK A, MAN HON WAH, HAVENS COURTNEY G, LU XIAOLING
Year of Publication 11.03.2020
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Year of Publication 11.03.2020
Patent
TREATMENT OF PROSTATE CANCER WITH TOR KINASE INHIBITORS
HEGE KRISTEN MAE, TSUJI TOSHIYA, NARLA RAMA K, MORTENSEN DEBORAH, FULTZ KIMBERLY ELIZABETH, RAYMON HEATHER
Year of Publication 24.06.2015
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Year of Publication 24.06.2015
Patent
Differential Effects of Iberdomide Versus Revlimid on Leukocyte Trafficking, Immune Activation and DLBCL Tumor Cell Killing
Nakayama, Yumi, Chiu, Hsiling, Narla, Rama K., Shakya, Arvind, Gamez, Jim, Wall, Isobelle, Papazoglou, Despoina, Apollonio, Benedetta, Ramsay, Alan G., Hagner, Patrick, Gandhi, Anita K
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
CC-99282 is a Novel Cereblon (CRBN) E3 Ligase Modulator (CELMoD) Agent with Enhanced Tumoricidal Activity in Preclinical Models of Lymphoma
Carrancio, Soraya, Groocock, Lynda, Janardhanan, Preethi, Jankeel, Diana, Galasso, Ryan, Guarinos, Carla, Narla, Rama K., Groza, Matthew, Leisten, Jim, Pierce, Daniel W., Rolfe, Mark, Lopez-Girona, Antonia
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
3 mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/Akt PATHWAY
ZHAO JINGJING, HARRIS ROY L, FULTZ KIMBERLY, LEE BRANDEN, SANKAR SABITA, SHEVLIN GRAZIELLA, PACKARD GARRICK, PERRIN NINKOVIC SOPHIE, SAPIENZA JOHN, RIGGS JENNIFER, NARLA RAMA K, MADAKAMUTIL LOUI, PAPA PATRICK, ELSNER JAN, MORTENSEN DEBORAH, PARNES JASON, XU WEIMING, TEHRANI LIDA
Year of Publication 12.07.2017
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Year of Publication 12.07.2017
Patent
TREATMENT OF CANCER WITH TOR KINASE INHIBITORS
XU SHUICHAN, HEGE KRISTEN MAE, NARLA RAMA K, LOPEZ GIRONA ANTONIA, RAYMON HEATHER, CHOPRA RAJESH
Year of Publication 23.07.2014
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Year of Publication 23.07.2014
Patent
SUBSTITUTED PYRROLOPYRIMIDINE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
HARRIS ROY L, ZHU DAN, TRAN TAM MINH, XU SHUICHAN, RAHEJA RAJ KUMAR, CALABRESE ANDREW ANTONY, NING YUHONG, RIGGS JENNIFER, ROBINSON DALE, NARLA RAMA K, JEFFY BRANDON, ELSNER JAN, HUANG DEHUA, BOYLAN JOHN, ERDMAN PAUL, NAGY MARK A, TEHRANI LIDA
Year of Publication 25.09.2015
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Year of Publication 25.09.2015
Patent
Abstract B177: Synthetic lethal approach identifies potent and selective TTK and CLK inhibitor with preclinical anticancer activity in triple-negative breast cancer model
Zhu, Dan, Deyanat-Yazdi, Gordafaried, Mikolon, David, Narla, Rama K., Peng, Sophie X., Ning, Yuhong, Riggs, Jennifer R., Boylan, John F.
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
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Journal Article
MTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE MTOR/PI3K/AKT PATHWAY
ZHAO JINGJING, HARRIS ROY L, FULTZ KIMBERLY, LEE BRANDEN, SANKAR SABITA, SHEVLIN GRAZIELLA, PACKARD GARRICK, PERRIN NINKOVIC SOPHIE, SAPIENZA JOHN, RIGGS JENNIFER, NARLA RAMA K, MADAKAMUTIL LOUI, PAPA PATRICK, ELSNER JAN, MORTENSEN DEBORAH, PARNES JASON, XU WEIMING, TEHRANI LIDA
Year of Publication 07.07.2011
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Year of Publication 07.07.2011
Patent
TREATMENT OF CANCER WITH TOR KINASE INHIBITORS
HEGE, KRISTEN MAE, NARLA, RAMA K, RAYMON, HEATHER, XU, SHUICHAN, LOPEZ-GIRONA, ANTONIA, CHOPRA, RAJESH
Year of Publication 10.10.2023
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Year of Publication 10.10.2023
Patent
1-ETHYL-7-(2-METHYL-6-(1H-1,2,4-TRIAZOL-3-YL)PYRIDIN-3-YL)-3,4-DIHYDROPYRAZINO[2,3-B]PYRAZIN-2(1H)-ONE FOR USE IN THE TREATMENT OF GLIOBLASTOMA MULTIFORME
HEGE, Kristen Mae, LOPEZ-GIRONA, Antonia, CHOPRA, Rajesh, XU, Shuichan, NARLA, Rama K, RAYMON, Heather
Year of Publication 21.12.2022
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Year of Publication 21.12.2022
Patent
TREATMENT OF CANCER WITH TOR KINASE INHIBITORS
HEGE, Kristen Mae, LOPEZ-GIRONA, Antonia, CHOPRA, Rajesh, XU, Shuichan, NARLA, Rama K, RAYMON, Heather
Year of Publication 01.09.2022
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Year of Publication 01.09.2022
Patent