In vivo imaging with two-photon microscopy to assess the tumor-selective binding of an anti-CD137 switch antibody
Kaneko, Chisato, Tsutsui, Haruka, Ozeki, Kazuhisa, Honda, Masaki, Haraya, Kenta, Narita, Yoshinori, Kamata-Sakurai, Mika, Kikuta, Junichi, Tabo, Mitsuyasu, Ishii, Masaru
Published in Scientific reports (22.03.2022)
Published in Scientific reports (22.03.2022)
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Journal Article
In vivo validation of the switch antibody concept: SPECT/CT imaging of the anti-CD137 switch antibody Sta-MB shows high uptake in tumors but low uptake in normal organs in human CD137 knock-in mice
Sugyo, Aya, Tsuji, Atsushi B, Sudo, Hitomi, Narita, Yoshinori, Taniguchi, Kenji, Nemoto, Takayuki, Isomura, Fumihisa, Awaya, Norihiro, Kamata-Sakurai, Mika, Higashi, Tatsuya
Published in Translational oncology (01.09.2022)
Published in Translational oncology (01.09.2022)
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Liposome-encapsulated CpG oligodeoxynucleotides as a potent adjuvant for inducing type 1 innate immunity
SUZUKI, Yoshinori, WAKITA, Daiko, KATOH, Hiroyuki, IKEDA, Hiroaki, NISHIMURA, Takashi, CHAMOTO, Kenji, NARITA, Yoshinori, TSUJI, Takemasa, TAKESHIMA, Tsuguhide, GYOBU, Hiroshi, KAWARADA, You, KONDO, Satoshi, AKIRA, Shizuo
Published in Cancer research (Chicago, Ill.) (01.12.2004)
Published in Cancer research (Chicago, Ill.) (01.12.2004)
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Potential differentiation of tumor bearing mouse CD11b+Gr-1+ immature myeloid cells into both suppressor macrophages and immunostimulatory dendritic cells
Narita, Yoshinori, Wakita, Daiko, Ohkur, Takayuk, Chamoto, Kenji, Nishimura, Takashi
Published in Biomedical Research (01.02.2009)
Published in Biomedical Research (01.02.2009)
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Th1 cell adjuvant therapy combined with tumor vaccination: a novel strategy for promoting CTL responses while avoiding the accumulation of Tregs
Zhang, Yue, Wakita, Daiko, Chamoto, Kenji, Narita, Yoshinori, Matsubara, Naoki, Kitamura, Hidemitsu, Nishimura, Takashi
Published in International immunology (01.02.2007)
Published in International immunology (01.02.2007)
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Sialyl lewisx antigen-expressing human CD4+ T and CD8+ T cells as initial immune responders in memory phenotype subsets
Zhang, Yue, Ohkuri, Takayuki, Wakita, Daiko, Narita, Yoshinori, Chamoto, Kenji, Kitamura, Hidemitsu, Nishimura, Takashi
Published in Journal of leukocyte biology (01.09.2008)
Published in Journal of leukocyte biology (01.09.2008)
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Journal Article
Anti‐IL‐6 receptor mAb eliminates myeloid‐derived suppressor cells and inhibits tumor growth by enhancing T‐cell responses
Sumida, Kentaro, Wakita, Daiko, Narita, Yoshinori, Masuko, Kazutaka, Terada, Satoshi, Watanabe, Kazue, Satoh, Takayuki, Kitamura, Hidemitsu, Nishimura, Takashi
Published in European journal of immunology (01.08.2012)
Published in European journal of immunology (01.08.2012)
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The key role of IL-6-arginase cascade for inducing dendritic cell-dependent CD4(+) T cell dysfunction in tumor-bearing mice
Narita, Yoshinori, Kitamura, Hidemitsu, Wakita, Daiko, Sumida, Kentaro, Masuko, Kazutaka, Terada, Satoshi, Nakano, Kiichiroh, Nishimura, Takashi
Published in The Journal of immunology (1950) (15.01.2013)
Published in The Journal of immunology (1950) (15.01.2013)
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Abstract 1851: Responses of a novel tumor selective anti-CD137 agonist antibody activated by elevated extracellular ATP in tumor microenvironment
Kamata-Sakurai, Mika, Narita, Yoshinori, Uchikawa, Ryo, Taniguchi, Kenji, Horikawa, Sayuri, Hamada, Koki, Hori, Yuji, Nemoto, Takayuki, Metsugi, Shoichi, Inatani, Michiyasu, Igawa, Tomoyuki
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Antibody to CD137 Activated by Extracellular Adenosine Triphosphate Is Tumor Selective and Broadly Effective In Vivo without Systemic Immune Activation
Kamata-Sakurai, Mika, Narita, Yoshinori, Hori, Yuji, Nemoto, Takayuki, Uchikawa, Ryo, Honda, Masaki, Hironiwa, Naoka, Taniguchi, Kenji, Shida-Kawazoe, Meiri, Metsugi, Shoichi, Miyazaki, Taro, Wada, Naoko A, Ohte, Yuki, Shimizu, Shun, Mikami, Hirofumi, Tachibana, Tatsuhiko, Ono, Natsuki, Adachi, Kenji, Sakiyama, Tetsushi, Matsushita, Tomochika, Kadono, Shojiro, Komatsu, Shun-Ichiro, Sakamoto, Akihisa, Horikawa, Sayuri, Hirako, Ayano, Hamada, Koki, Naoi, Sotaro, Savory, Nasa, Satoh, Yasuko, Sato, Motohiko, Noguchi, Yuki, Shinozuka, Junko, Kuroi, Haruka, Ito, Ami, Wakabayashi, Tetsuya, Kamimura, Masaki, Isomura, Fumihisa, Tomii, Yasushi, Sawada, Noriaki, Kato, Atsuhiko, Ueda, Otoya, Nakanishi, Yoshito, Endo, Mika, Jishage, Kou-Ichi, Kawabe, Yoshiki, Kitazawa, Takehisa, Igawa, Tomoyuki
Published in Cancer discovery (01.01.2021)
Published in Cancer discovery (01.01.2021)
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Abstract 2747: Anti-glypican-3 monoclonal antibody (codrituzumab/GC33/RO5137382) treatment enhances tumor infiltration of PD-L1-positive macrophages, and combination therapy with anti-PD-L1 monoclonal antibody promotes antitumor effects
Endo, Mika, Kinoshita, Yasuko, Adachi, Kenji, Narita, Yoshinori, Amano, Jun, Kato, Atsuhiko, Watanabe, Takeshi, Kayukawa, Yoko, Miyazaki, Yoko, Ohtomo, Toshihiko
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 5518: Single cell RNA sequencing revealed that the mechanism of the synergistic efficacy of STA551 and immune checkpoint inhibitor results from the induction of highly activated T cells in tumor
Uchikawa, Ryo, Takakuwa, Kazuya, Mikami, Hirofumi, Metsugi, Shoichi, Taniguchi, Kenji, Narita, Yoshinori, Kamata-Sakurai, Mika
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
암의 치료에 이용하기 위한 항CD137 항원 결합 분자
NARITA YOSHINORI, TANIGUCHI KENJI, HORIKAWA SAYURI, HAMADA KOKI, ONO NATSUKI, MIKAMI HIROFUMI, UCHIKAWA RYO, SAKURAI MIKA
Year of Publication 18.10.2022
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Year of Publication 18.10.2022
Patent
ANTI-CD137 ANTIGEN BINDING MOLECULES AND USES THEREOF
HORI YUJI, KADONO SHOJIRO, IGAWA TOMOYUKI, SHIMIZU SHUN, HAYASAKA AKIRA, SAKURAI MIKA, SAVORY NASA, NARITA YOSHINORI, KAWACHI HIROKI, KAMIMURA MASAKI, TATSUMI KANAKO, HASEGAWA MASAMI, MIMOTO FUTA, HIRONIWA NAOKA, MIYAZAKI TARO, KAWAI TAKEAKI, KAMIKAWA TAKEYUKI
Year of Publication 04.06.2024
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Year of Publication 04.06.2024
Patent
ANTI-CD137 ANTIGEN-BINDING MOLECULE FOR USE IN CANCER TREATMENT
TANIGUCHI, Kenji, HAMADA, Koki, ONO, Natsuki, UCHIKAWA, Ryo, SAKURAI, Mika, HORIKAWA, Sayuri, NARITA, Yoshinori, MIKAMI, Hirofumi
Year of Publication 19.08.2021
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Year of Publication 19.08.2021
Patent
CSF-1-dependent red pulp macrophages regulate CD4 T cell responses
Kurotaki, Daisuke, Kon, Shigeyuki, Bae, Kyeonghwa, Ito, Koyu, Matsui, Yutaka, Nakayama, Yosuke, Kanayama, Masashi, Kimura, Chiemi, Narita, Yoshinori, Nishimura, Takashi, Iwabuchi, Kazuya, Mack, Matthias, van Rooijen, Nico, Sakaguchi, Shimon, Uede, Toshimitsu, Morimoto, Junko
Published in The Journal of immunology (1950) (15.02.2011)
Published in The Journal of immunology (1950) (15.02.2011)
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METHOD FOR FORMING MULTILAYER COATED FILM
KAWABATA TAKAYUKI, YAMAZAKI AKIRA, ANPO KEIJI, NARITA YOSHINORI, HASE MASAKO
Year of Publication 08.11.2018
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Year of Publication 08.11.2018
Patent