Development of protein degradation inducers of oncogenic BCR‐ABL protein by conjugation of ABL kinase inhibitors and IAP ligands
Shibata, Norihito, Miyamoto, Naoki, Nagai, Katsunori, Shimokawa, Kenichiro, Sameshima, Tomoya, Ohoka, Nobumichi, Hattori, Takayuki, Imaeda, Yasuhiro, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko
Published in Cancer science (01.08.2017)
Published in Cancer science (01.08.2017)
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In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs)
Ohoka, Nobumichi, Okuhira, Keiichiro, Ito, Masahiro, Nagai, Katsunori, Shibata, Norihito, Hattori, Takayuki, Ujikawa, Osamu, Shimokawa, Kenichiro, Sano, Osamu, Koyama, Ryokichi, Fujita, Hisashi, Teratani, Mika, Matsumoto, Hirokazu, Imaeda, Yasuhiro, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko
Published in The Journal of biological chemistry (17.03.2017)
Published in The Journal of biological chemistry (17.03.2017)
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Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-Dependent Protein Eraser (SNIPER)
Ohoka, Nobumichi, Ujikawa, Osamu, Shimokawa, Kenichiro, Sameshima, Tomoya, Shibata, Norihito, Hattori, Takayuki, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko
Published in Chemical & pharmaceutical bulletin (01.03.2019)
Published in Chemical & pharmaceutical bulletin (01.03.2019)
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SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib
Ohoka, Nobumichi, Nagai, Katsunori, Shibata, Norihito, Hattori, Takayuki, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko
Published in Cancer science (01.05.2017)
Published in Cancer science (01.05.2017)
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Targeting the Allosteric Site of Oncoprotein BCR-ABL as an Alternative Strategy for Effective Target Protein Degradation
Shimokawa, Kenichiro, Shibata, Norihito, Sameshima, Tomoya, Miyamoto, Naoki, Ujikawa, Osamu, Nara, Hiroshi, Ohoka, Nobumichi, Hattori, Takayuki, Cho, Nobuo, Naito, Mikihiko
Published in ACS medicinal chemistry letters (12.10.2017)
Published in ACS medicinal chemistry letters (12.10.2017)
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Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response
Szewczyk, Magdalena M, Ishikawa, Yoshinori, Organ, Shawna, Sakai, Nozomu, Li, Fengling, Halabelian, Levon, Ackloo, Suzanne, Couzens, Amber L, Eram, Mohammad, Dilworth, David, Fukushi, Hideto, Harding, Rachel, Dela Seña, Carlo C, Sugo, Tsukasa, Hayashi, Kozo, McLeod, David, Zepeda, Carlos, Aman, Ahmed, Sánchez-Osuna, Maria, Bonneil, Eric, Takagi, Shinji, Al-Awar, Rima, Tyers, Mike, Richard, Stephane, Takizawa, Masayuki, Gingras, Anne-Claude, Arrowsmith, Cheryl H, Vedadi, Masoud, Brown, Peter J, Nara, Hiroshi, Barsyte-Lovejoy, Dalia
Published in Nature communications (14.05.2020)
Published in Nature communications (14.05.2020)
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Pharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase
Shibata, Norihito, Shimokawa, Kenichiro, Nagai, Katsunori, Ohoka, Nobumichi, Hattori, Takayuki, Miyamoto, Naoki, Ujikawa, Osamu, Sameshima, Tomoya, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko
Published in Scientific reports (10.09.2018)
Published in Scientific reports (10.09.2018)
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Discovery of Novel, Highly Potent, and Selective Quinazoline-2-carboxamide-Based Matrix Metalloproteinase (MMP)-13 Inhibitors without a Zinc Binding Group Using a Structure-Based Design Approach
Nara, Hiroshi, Sato, Kenjiro, Naito, Takako, Mototani, Hideyuki, Oki, Hideyuki, Yamamoto, Yoshio, Kuno, Haruhiko, Santou, Takashi, Kanzaki, Naoyuki, Terauchi, Jun, Uchikawa, Osamu, Kori, Masakuni
Published in Journal of medicinal chemistry (13.11.2014)
Published in Journal of medicinal chemistry (13.11.2014)
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Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response
Szewczyk, Magdalena M, Ishikawa, Yoshinori, Organ, Shawna, Sakai, Nozomu, Li, Fengling, Halabelian, Levon, Ackloo, Suzanne, Couzens, Amber L, Eram, Mohammad, Dilworth, David, Fukushi, Hideto, Harding, Rachel, Dela Seña, Carlo C, Sugo, Tsukasa, Hayashi, Kozo, McLeod, David, Zepeda, Carlos, Aman, Ahmed, Sánchez-Osuna, Maria, Bonneil, Eric, Takagi, Shinji, Al-Awar, Rima, Tyers, Mike, Richard, Stephane, Takizawa, Masayuki, Gingras, Anne-Claude, Arrowsmith, Cheryl H, Vedadi, Masoud, Brown, Peter J, Nara, Hiroshi, Barsyte-Lovejoy, Dalia
Published in Nature communications (26.05.2020)
Published in Nature communications (26.05.2020)
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