Discovery and Development of Metal-Catalyzed Coupling Reactions in the Synthesis of Dasabuvir, an HCV-Polymerase Inhibitor
Barnes, David M, Shekhar, Shashank, Dunn, Travis B, Barkalow, Jufang H, Chan, Vincent S, Franczyk, Thaddeus S, Haight, Anthony R, Hengeveld, John E, Kolaczkowski, Lawrence, Kotecki, Brian J, Liang, Guangxin, Marek, James C, McLaughlin, Maureen A, Montavon, Donna K, Napier, James J
Published in Journal of organic chemistry (19.04.2019)
Published in Journal of organic chemistry (19.04.2019)
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Use of a Polymer Additive To Enhance Impurity Rejection in the Crystallization of a Pharmaceutical Compound
Czyzewski, Ann M, Chen, Shuang, Bhamidi, Venkateswarlu, Yu, Su, Marsden, Ian, Ding, Chen, Becker, Calvin, Napier, James J
Published in Organic process research & development (20.10.2017)
Published in Organic process research & development (20.10.2017)
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Optimization of Chromone-2-carboxamide Melanin Concentrating Hormone Receptor 1 Antagonists: Assessment of Potency, Efficacy, and Cardiovascular Safety
Lynch, John K, Freeman, Jennifer C, Judd, Andrew S, Iyengar, Rajesh, Mulhern, Mathew, Zhao, Gang, Napier, James J, Wodka, Dariusz, Brodjian, Sevan, Dayton, Brian D, Falls, Doug, Ogiela, Christopher, Reilly, Regina M, Campbell, Thomas J, Polakowski, James S, Hernandez, Lisa, Marsh, Kennan C, Shapiro, Robin, Knourek-Segel, Victoria, Droz, Brian, Bush, Eugene, Brune, Michael, Preusser, Lee C, Fryer, Ryan M, Reinhart, Glenn A, Houseman, Kathryn, Diaz, Gilbert, Mikhail, Ann, Limberis, James T, Sham, Hing L, Collins, Christine A, Kym, Philip R
Published in Journal of medicinal chemistry (02.11.2006)
Published in Journal of medicinal chemistry (02.11.2006)
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An enantioselective and highly convergent synthesis of (+)-ikarugamycin
Boeckman, Robert K, Weidner, Charles H, Perni, Robert B, Napier, James J
Published in Journal of the American Chemical Society (01.09.1989)
Published in Journal of the American Chemical Society (01.09.1989)
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Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity
Souers, Andrew J., Gao, Ju, Wodka, Dariusz, Judd, Andrew S., Mulhern, Mathew M., Napier, James J., Brune, Michael E., Bush, Eugene N., Brodjian, Sevan J., Dayton, Brian D., Shapiro, Robin, Hernandez, Lisa E., Marsh, Kennan C., Sham, Hing L., Collins, Christine A., Kym, Philip R.
Published in Bioorganic & medicinal chemistry letters (02.06.2005)
Published in Bioorganic & medicinal chemistry letters (02.06.2005)
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Screening for Cardiovascular Safety: A Structure−Activity Approach for Guiding Lead Selection of Melanin Concentrating Hormone Receptor 1 Antagonists
Kym, Philip R, Souers, Andrew J, Campbell, Thomas J, Lynch, John K, Judd, Andrew S, Iyengar, Rajesh, Vasudevan, Anil, Gao, Ju, Freeman, Jennifer C, Wodka, Dariusz, Mulhern, Mathew, Zhao, Gang, Wagaw, Seble H, Napier, James J, Brodjian, Sevan, Dayton, Brian D, Reilly, Regina M, Segreti, Jason A, Fryer, Ryan M, Preusser, Lee C, Reinhart, Glenn A, Hernandez, Lisa, Marsh, Kennan C, Sham, Hing L, Collins, Christine A, Polakowski, James S
Published in Journal of medicinal chemistry (06.04.2006)
Published in Journal of medicinal chemistry (06.04.2006)
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Evolution of the synthetic process to prepare the tripeptide segment of ABT-510
Becker, Calvin L, Califano, Jean Christophe, Tolle, John C, Napier, James J, Kolaczkowski, Lawrence, Chang, Sou-Jen, Tian, Zhenping, Manna, Sukamar
Published in Advances in experimental medicine and biology (2009)
Published in Advances in experimental medicine and biology (2009)
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Impurity rejection in the crystallization of ABT-510 as a method to establish starting material specifications
Tolle, John C, Becker, Calvin L, Califano, Jean C, Chang, Jane L, Gernhardt, Kevin, Napier, James J, Wittenberger, Steven J, Yuan, Judy
Published in Advances in experimental medicine and biology (2009)
Published in Advances in experimental medicine and biology (2009)
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Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: The effects of chirality on substituted indan-1-ylamines
Souers, Andrew J., Iyengar, Rajesh R., Judd, Andrew S., Beno, David W.A., Gao, Ju, Zhao, Gang, Brune, Michael E., Napier, James J., Mulhern, Mathew M., Lynch, John K., Freeman, Jennifer C., Wodka, Dariusz, Chen, Chong J., Falls, H. Doug, Brodjian, Sevan, Dayton, Brian D., Diaz, Gilbert J., Bush, Eugene N., Shapiro, Robin, Droz, Brian A., Knourek-Segel, Victoria, Hernandez, Lisa E., Marsh, Kennan C., Reilly, Regina M., Sham, Hing L., Collins, Christine A., Kym, Philip R.
Published in Bioorganic & medicinal chemistry letters (15.02.2007)
Published in Bioorganic & medicinal chemistry letters (15.02.2007)
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Stereochemistry of benzodihydrofuran-2-carboxylic acid ester photorearrangement
Schultz, Arthur G, Napier, James J, Sundararaman, Padmanabhan
Published in Journal of the American Chemical Society (01.06.1984)
Published in Journal of the American Chemical Society (01.06.1984)
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Synthetic applications of heteroatom-directed photoarylation. Benzo[b]furan ring construction
Schultz, Arthur G, Napier, James J, Ravichandran, Ramanathan
Published in Journal of organic chemistry (01.10.1983)
Published in Journal of organic chemistry (01.10.1983)
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Stereospecific benzodihydrofuran photorearrangement
Schultz, Arthur G, Napier, James J, Lee, Ronald
Published in Journal of organic chemistry (01.02.1979)
Published in Journal of organic chemistry (01.02.1979)
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