Epigenetic Regulation of Organic Anion Transporting Polypeptide 1B3 in Cancer Cell Lines
Imai, Satoki, Kikuchi, Ryota, Tsuruya, Yuri, Naoi, Sotaro, Nishida, Sho, Kusuhara, Hiroyuki, Sugiyama, Yuichi
Published in Pharmaceutical research (01.11.2013)
Published in Pharmaceutical research (01.11.2013)
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Journal Article
Improved Liver Function and Relieved Pruritus after 4-Phenylbutyrate Therapy in a Patient with Progressive Familial Intrahepatic Cholestasis Type 2
Naoi, Sotaro, MS, Hayashi, Hisamitsu, PhD, Inoue, Takeshi, MD, Tanikawa, Ken, MD, Igarashi, Koji, PhD, Nagasaka, Hironori, MD, PhD, Kage, Masayoshi, MD, PhD, Takikawa, Hajime, MD, PhD, Sugiyama, Yuichi, PhD, Inui, Ayano, MD, PhD, Nagai, Toshiro, MD, PhD, Kusuhara, Hiroyuki, PhD
Published in The Journal of pediatrics (01.05.2014)
Published in The Journal of pediatrics (01.05.2014)
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Journal Article
Successful treatment with 4-phenylbutyrate in a patient with benign recurrent intrahepatic cholestasis type 2 refractory to biliary drainage and bilirubin absorption
Hayashi, Hisamitsu, Naoi, Sotaro, Hirose, Yu, Matsuzaka, Yusuke, Tanikawa, Ken, Igarashi, Koji, Nagasaka, Hironori, Kage, Masayoshi, Inui, Ayano, Kusuhara, Hiroyuki
Published in Hepatology research (01.02.2016)
Published in Hepatology research (01.02.2016)
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Journal Article
SAIL66, a next generation CLDN6-targeting T-cell engager, demonstrates potent antitumor efficacy through dual binding to CD3/CD137
Kamikawa, Takayuki, Kimura, Naoki, Ishii, Shinya, Muraoka, Masaru, Kodama, Tatsushi, Taniguchi, Kenji, Yoshimoto, Moe, Miura-Okuda, Momoko, Uchikawa, Ryo, Kato, Chie, Shinozuka, Junko, Akai, Sho, Naoi, Sotaro, Tomioka, Nanami, Nagaya, Nishiki, Pang, Chai Ling, Garvita, Gupta, Feng, Shu, Shimada, Mei, Kamata-Sakurai, Mika, Aburatani, Hiroyuki, Kitazawa, Takehisa, Igawa, Tomoyuki
Published in Journal for immunotherapy of cancer (14.10.2024)
Published in Journal for immunotherapy of cancer (14.10.2024)
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Journal Article
Assessment of ATP8B1 Deficiency in Pediatric Patients With Cholestasis Using Peripheral Blood Monocyte-Derived Macrophages
Hayashi, Hisamitsu, Naoi, Sotaro, Togawa, Takao, Hirose, Yu, Kondou, Hiroki, Hasegawa, Yasuhiro, Abukawa, Daiki, Sasaki, Mika, Muroya, Koji, Watanabe, Satoshi, Nakano, Satoshi, Minowa, Kei, Inui, Ayano, Fukuda, Akinari, Kasahara, Mureo, Nagasaka, Hironori, Bessho, Kazuhiko, Suzuki, Mitsuyoshi, Kusuhara, Hiroyuki
Published in EBioMedicine (01.01.2018)
Published in EBioMedicine (01.01.2018)
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Physiologically based pharmacokinetic (PBPK) model that describes enhanced FcRn-dependent distribution of monoclonal antibodies (mAbs) by pI-engineering in mice
Naoi, Sotaro, Yamane, Mizuki, Nemoto, Takayuki, Kato, Motohiro, Saito, Ryoichi, Tachibana, Tatsuhiko
Published in Drug metabolism and pharmacokinetics (01.12.2023)
Published in Drug metabolism and pharmacokinetics (01.12.2023)
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Journal Article
Ubiquitination is associated with lysosomal degradation of cell surface‐resident ATP‐binding cassette transporter A1 (ABCA1) through the endosomal sorting complex required for transport (ESCRT) pathway
Mizuno, Tadahaya, Hayashi, Hisamitsu, Naoi, Sotaro, Sugiyama, Yuichi
Published in Hepatology (Baltimore, Md.) (01.08.2011)
Published in Hepatology (Baltimore, Md.) (01.08.2011)
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Antibody to CD137 Activated by Extracellular Adenosine Triphosphate Is Tumor Selective and Broadly Effective In Vivo without Systemic Immune Activation
Kamata-Sakurai, Mika, Narita, Yoshinori, Hori, Yuji, Nemoto, Takayuki, Uchikawa, Ryo, Honda, Masaki, Hironiwa, Naoka, Taniguchi, Kenji, Shida-Kawazoe, Meiri, Metsugi, Shoichi, Miyazaki, Taro, Wada, Naoko A, Ohte, Yuki, Shimizu, Shun, Mikami, Hirofumi, Tachibana, Tatsuhiko, Ono, Natsuki, Adachi, Kenji, Sakiyama, Tetsushi, Matsushita, Tomochika, Kadono, Shojiro, Komatsu, Shun-Ichiro, Sakamoto, Akihisa, Horikawa, Sayuri, Hirako, Ayano, Hamada, Koki, Naoi, Sotaro, Savory, Nasa, Satoh, Yasuko, Sato, Motohiko, Noguchi, Yuki, Shinozuka, Junko, Kuroi, Haruka, Ito, Ami, Wakabayashi, Tetsuya, Kamimura, Masaki, Isomura, Fumihisa, Tomii, Yasushi, Sawada, Noriaki, Kato, Atsuhiko, Ueda, Otoya, Nakanishi, Yoshito, Endo, Mika, Jishage, Kou-Ichi, Kawabe, Yoshiki, Kitazawa, Takehisa, Igawa, Tomoyuki
Published in Cancer discovery (01.01.2021)
Published in Cancer discovery (01.01.2021)
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AP2 adaptor complex mediates bile salt export pump internalization and modulates its hepatocanalicular expression and transport function
Hayashi, Hisamitsu, Inamura, Kaori, Aida, Kensuke, Naoi, Sotaro, Horikawa, Reiko, Nagasaka, Hironori, Takatani, Tomozumi, Fukushima, Tamio, Hattori, Asami, Yabuki, Takashi, Horii, Ikuo, Sugiyama, Yuichi
Published in Hepatology (Baltimore, Md.) (01.06.2012)
Published in Hepatology (Baltimore, Md.) (01.06.2012)
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Journal Article
METHOD FOR PREDICTING IN VIVO PHARMACOKINETICS OF MOLECULE
OZEKI, Kazuhisa, TSUTSUI, Haruka, OHMINATO, Noriaki, NAOI, Sotaro, SATO, Kazuki, NOGUCHI, Yuki
Year of Publication 24.11.2022
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Year of Publication 24.11.2022
Patent
Intractable itch relieved by 4-phenylbutyrate therapy in patients with progressive familial intrahepatic cholestasis type 1
Hasegawa, Yasuhiro, Hayashi, Hisamitsu, Naoi, Sotaro, Kondou, Hiroki, Bessho, Kazuhiko, Igarashi, Koji, Hanada, Kentaro, Nakao, Kie, Kimura, Takeshi, Konishi, Akiko, Nagasaka, Hironori, Miyoshi, Yoko, Ozono, Keiichi, Kusuhara, Hiroyuki
Published in Orphanet journal of rare diseases (15.07.2014)
Published in Orphanet journal of rare diseases (15.07.2014)
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Journal Article
Engineering CD3/CD137 Dual Specificity into a DLL3-Targeted T-Cell Engager Enhances T-Cell Infiltration and Efficacy against Small-Cell Lung Cancer
Mikami, Hirofumi, Feng, Shu, Matsuda, Yutaka, Ishii, Shinya, Naoi, Sotaro, Azuma, Yumiko, Nagano, Hiroaki, Asanuma, Kentaro, Kayukawa, Yoko, Tsunenari, Toshiaki, Kamikawaji, Shogo, Iwabuchi, Ryutaro, Shinozuka, Junko, Yamazaki, Masaki, Kuroi, Haruka, Ho, Samantha Shu Wen, Gan, Siok Wan, Chichili, Priyanka, Pang, Chai Ling, Yeo, Chiew Ying, Shimizu, Shun, Hironiwa, Naoka, Kinoshita, Yasuko, Shimizu, Yuichiro, Sakamoto, Akihisa, Muraoka, Masaru, Takahashi, Noriyuki, Kawa, Tatsuya, Shiraiwa, Hirotake, Mimoto, Futa, Kashima, Kenji, Kamata-Sakurai, Mika, Ishikawa, Shumpei, Aburatani, Hiroyuki, Kitazawa, Takehisa, Igawa, Tomoyuki
Published in Cancer immunology research (04.06.2024)
Published in Cancer immunology research (04.06.2024)
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DLL3 USES OF DLL3-TARGETTING MULTISPECIFIC ANTIGEN-BINDING MOLECULES
IGAWA TOMOYUKI, HO SHU WEN SAMANTHA, MIKAMI HIROFUMI, MATSUDA YUTAKA, NAOI SOTARO, FENG SHU, KAWAI YUMIKO, TSUNENARI TOSHIAKI
Year of Publication 07.04.2023
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Year of Publication 07.04.2023
Patent
Sorting Nexin 27 Interacts with Multidrug Resistance-associated Protein 4 (MRP4) and Mediates Internalization of MRP4
Hayashi, Hisamitsu, Naoi, Sotaro, Nakagawa, Takayuki, Nishikawa, Toru, Fukuda, Hiroyuki, Imajoh-Ohmi, Shinobu, Kondo, Ayano, Kubo, Kiyotaka, Yabuki, Takashi, Hattori, Asami, Hirouchi, Masakazu, Sugiyama, Yuichi
Published in The Journal of biological chemistry (27.04.2012)
Published in The Journal of biological chemistry (27.04.2012)
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