Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ
Brownell, James E., Sintchak, Michael D., Gavin, James M., Liao, Hua, Bruzzese, Frank J., Bump, Nancy J., Soucy, Teresa A., Milhollen, Michael A., Yang, Xiaofeng, Burkhardt, Anne L., Ma, Jingya, Loke, Huay-Keng, Lingaraj, Trupti, Wu, Dongyun, Hamman, Kristin B., Spelman, James J., Cullis, Courtney A., Langston, Steven P., Vyskocil, Stepan, Sells, Todd B., Mallender, William D., Visiers, Irache, Li, Ping, Claiborne, Christopher F., Rolfe, Mark, Bolen, Joseph B., Dick, Lawrence R.
Published in Molecular cell (15.01.2010)
Published in Molecular cell (15.01.2010)
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Mechanistic Study of Uba5 Enzyme and the Ufm1 Conjugation Pathway
Gavin, James M., Hoar, Kara, Xu, Qing, Ma, Jingya, Lin, Yafang, Chen, Jiejin, Chen, Wei, Bruzzese, Frank J., Harrison, Sean, Mallender, William D., Bump, Nancy J., Sintchak, Michael D., Bence, Neil F., Li, Ping, Dick, Lawrence R., Gould, Alexandra E., Chen, Jesse J.
Published in The Journal of biological chemistry (15.08.2014)
Published in The Journal of biological chemistry (15.08.2014)
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Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905)
Duffey, Matthew O, Vos, Tricia J, Adams, Ruth, Alley, Jennifer, Anthony, Justin, Barrett, Cynthia, Bharathan, Indu, Bowman, Douglas, Bump, Nancy J, Chau, Ryan, Cullis, Courtney, Driscoll, Denise L, Elder, Amy, Forsyth, Nancy, Frazer, Jonathan, Guo, Jianping, Guo, Luyi, Hyer, Marc L, Janowick, David, Kulkarni, Bheemashankar, Lai, Su-Jen, Lasky, Kerri, Li, Gang, Li, Jing, Liao, Debra, Little, Jeremy, Peng, Bo, Qian, Mark G, Reynolds, Dominic J, Rezaei, Mansoureh, Scott, Margaret Porter, Sells, Todd B, Shinde, Vaishali, Shi, Qiuju Judy, Sintchak, Michael D, Soucy, Francois, Sprott, Kevin T, Stroud, Stephen G, Nestor, Michelle, Visiers, Irache, Weatherhead, Gabriel, Ye, Yingchun, D’Amore, Natalie
Published in Journal of medicinal chemistry (12.01.2012)
Published in Journal of medicinal chemistry (12.01.2012)
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Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35
Bump, N.J. (BASF Bioresearch Corporation, Worchester, MA.), Hackett, M, Hugunin, M, Seshagiri, S, Brady, K, Chen, P, Ferenz, C, Franklin, S, Ghayur, T, Li, P
Published in Science (American Association for the Advancement of Science) (29.09.1995)
Published in Science (American Association for the Advancement of Science) (29.09.1995)
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Mechanistic Studies of Substrate-assisted Inhibition of Ubiquitin-activating Enzyme by Adenosine Sulfamate Analogues
Chen, Jesse J., Tsu, Christopher A., Gavin, James M., Milhollen, Michael A., Bruzzese, Frank J., Mallender, William D., Sintchak, Michael D., Bump, Nancy J., Yang, Xiaofeng, Ma, Jingya, Loke, Huay-Keng, Xu, Qing, Li, Ping, Bence, Neil F., Brownell, James E., Dick, Lawrence R.
Published in The Journal of biological chemistry (25.11.2011)
Published in The Journal of biological chemistry (25.11.2011)
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Journal Article
Activation of a CrmA-insensitive, p35-sensitive Pathway in Ionizing Radiation-induced Apoptosis
Datta, Rakesh, Kojima, Hiromi, Banach, David, Bump, Nancy J., Talanian, Robert V., Alnemri, Emad S., Weichselbaum, Ralph R., Wong, Winnie W., Kufe, Donald W.
Published in The Journal of biological chemistry (17.01.1997)
Published in The Journal of biological chemistry (17.01.1997)
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Purification and kinetic characterization of recombinant human mitogen-activated protein kinase kinase kinase COT and the complexes with its cellular partner NF-κB1 p105
Jia, Yong, Quinn, Christopher M., Bump, Nancy J., Clark, Kevin M., Clabbers, Anca, Hardman, Jennifer, Gagnon, Andrew, Kamens, Joanne, Tomlinson, Medha J., Wishart, Neil, Allen, Hamish
Published in Archives of biochemistry and biophysics (01.09.2005)
Published in Archives of biochemistry and biophysics (01.09.2005)
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Journal Article
Inhibition of ICE Family Proteases by Baculovirus Antiapoptotic Protein p53
Bump, Nancy J., Hackett, Maria, Hugunin, Margaret, Seshagiri, Somasekar, Brady, Kenneth, Chen, Patrick, Ferenz, Catherine, Franklin, Simon, Ghayur, Tariq, Li, Ping, Licari, Peter, Mankovich, John, Shi, Lianfa, Greenberg, Arnold H., Miller, Lois K., Wong, Winnie W.
Published in Science (American Association for the Advancement of Science) (29.09.1995)
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Published in Science (American Association for the Advancement of Science) (29.09.1995)
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Isolation and Subunit Composition of Tuftsin Receptor
Bump, Nancy J., Lee, James, Wleklik, Marek, Reichler, Judith, Najjar, Victor A.
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.1986)
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.1986)
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Journal Article
Method of identifying inhibitors of Tie-2
Bump, Nancy J, Arnold, Lee D, Dixon, Richard W, Hoeffken, Hans Wolfgang, Allen, Karen, Bellamacina, Cornelia
Year of Publication 06.05.2008
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Year of Publication 06.05.2008
Patent
Method of identifying inhibitors of Tie-2
ARNOLD LEE D, BELLAMACINA CORNELIA, BUMP NANCY J, ALLEN KAREN, DIXON RICHARD W, HOEFFKEN HANS WOLFGANG
Year of Publication 06.05.2008
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Year of Publication 06.05.2008
Patent
Method of identifying inhibitors of Tie-2
ARNOLD LEE D, HEOFFKEN HANS WOLFGANG, BELLAMACINA CORNELIA, BUMP NANCY J, ALLEN KAREN, DIXON RICHARD W
Year of Publication 01.05.2003
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Year of Publication 01.05.2003
Patent
METHOD OF IDENTIFYING INHIBITORS OF TIE-2
ARNOLD, LEE, D, BUMP, NANCY, J, ALLEN, KAREN, DIXON, RICHARD, W, HOEFFKEN, HANS, WOLFGANG, BELLAMACINA, CORNELIA
Year of Publication 02.01.2003
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Year of Publication 02.01.2003
Patent
METHOD OF IDENTIFYING INHIBITORS OF TIE-2
ARNOLD, LEE, D, BUMP, NANCY, J, ALLEN, KAREN, DIXON, RICHARD, W, HOEFFKEN, HANS, WOLFGANG, BELLAMACINA, CORNELIA
Year of Publication 02.05.2002
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Year of Publication 02.05.2002
Patent
Method of identifying inhibitors of TIE-2
CORNELIA BELLAMACINA, RICHARD W. DIXON, NANCY, J. BUMP, KAREN ALLEN, HANS, WOLFGANG HOEFFKEN, LEE D. ARNOLD
Year of Publication 08.10.2001
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Year of Publication 08.10.2001
Patent