Ziritaxestat Drug–Drug Interaction with Oral Contraceptives: Role of SULT1E1 Inhibition
Helmer, Eric, Karimian, Negin, Van Assche, Karen, Seghers, Ineke, Le Tallec, Sandrine, Cherala, Ganesh, Scott, Graham, Namour, Florence S.
Published in Clinical pharmacology and therapeutics (01.10.2022)
Published in Clinical pharmacology and therapeutics (01.10.2022)
Get full text
Journal Article
Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Modeling of Filgotinib (GLPG0634), a Selective JAK1 Inhibitor, in Support of Phase IIB Dose Selection
Namour, Florence, Diderichsen, Paul Matthias, Cox, Eugène, Vayssière, Béatrice, Van der Aa, Annegret, Tasset, Chantal, Van‘t Klooster, Gerben
Published in Clinical pharmacokinetics (01.08.2015)
Published in Clinical pharmacokinetics (01.08.2015)
Get full text
Journal Article
Drug-drug interaction prediction of ziritaxestat using a physiologically based enzyme and transporter pharmacokinetic network interaction model
Perrier, Jeremy, Gualano, Virginie, Helmer, Eric, Namour, Florence, Lukacova, Viera, Taneja, Amit
Published in Clinical and translational science (01.11.2023)
Published in Clinical and translational science (01.11.2023)
Get full text
Journal Article
Safety, pharmacokinetics and pharmacodynamics of GLPG0974, a potent and selective FFA2 antagonist, in healthy male subjects
Namour, Florence, Galien, René, Van Kaem, Tim, Van der Aa, Annegret, Vanhoutte, Frédéric, Beetens, Johan, Klooster, Gerben
Published in British journal of clinical pharmacology (01.07.2016)
Published in British journal of clinical pharmacology (01.07.2016)
Get full text
Journal Article
Identification of a 4‑(Hydroxymethyl)diarylhydantoin as a Selective Androgen Receptor Modulator
Nique, François, Hebbe, Séverine, Triballeau, Nicolas, Peixoto, Christophe, Lefrançois, Jean-Michel, Jary, Hélène, Alvey, Luke, Manioc, Murielle, Housseman, Christopher, Klaassen, Hugo, Van Beeck, Kris, Guédin, Denis, Namour, Florence, Minet, Dominque, Van der Aar, Ellen, Feyen, Jean, Fletcher, Stephen, Blanqué, Roland, Robin-Jagerschmidt, Catherine, Deprez, Pierre
Published in Journal of medicinal chemistry (11.10.2012)
Published in Journal of medicinal chemistry (11.10.2012)
Get full text
Journal Article
Effects of Nandrolone in the Counteraction of Skeletal Muscle Atrophy in a Mouse Model of Muscle Disuse: Molecular Biology and Functional Evaluation
Camerino, Giulia Maria, Desaphy, Jean-François, De Bellis, Michela, Capogrosso, Roberta Francesca, Cozzoli, Anna, Dinardo, Maria Maddalena, Caloiero, Roberta, Musaraj, Kejla, Fonzino, Adriano, Conte, Elena, Jagerschmidt, Catherine, Namour, Florence, Liantonio, Antonella, De Luca, Annamaria, Conte Camerino, Diana, Pierno, Sabata
Published in PloS one (11.06.2015)
Published in PloS one (11.06.2015)
Get full text
Journal Article
The Relative Bioavailability and Effects of Food and Acid‐Reducing Agents on Filgotinib Tablets in Healthy Subjects
Anderson, Kacey, Zheng, Hao, Kotecha, Mona, Cuvin, Jennifer, Scott, Bob, Sharma, Shringi, Qin, Ann Ran‐Ran, Namour, Florence, Xin, Yan
Published in Clinical pharmacology in drug development (01.07.2019)
Published in Clinical pharmacology in drug development (01.07.2019)
Get full text
Journal Article
Mo1234 The FFA2 Antagonist GLPG0974: A Promising Approach to Treat Neutrophil-Driven Inflammation
Vanhoutte, Frédéric P, Namour, Florence S, Dupont, Sonia, Pizzonero, Mathieu, De Vos, Steve, Sanière, Laurent, van der Aa, Annegret, Beetens, Johan, van 't Klooster, Gerben
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
Get full text
Journal Article
188 Exploration of GLPG0634, the First Selective JAK1 Inhibitor, in Inflammatory Bowel Disease Is Supported by Early Clinical Results and Mouse DSS-Colitis Data
Galien, Rene, Merciris, Didier, Vanhoutte, Frédéric P, Delachaume, Carole, Namour, Florence S, Vayssière, Béatrice, Van der Aa, Annegret, Brys, Reginald, van't Klooster, Gerben A
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
Get full text
Journal Article
Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization
Blanqué, Roland, Lepescheux, Liên, Auberval, Marielle, Minet, Dominique, Merciris, Didier, Cottereaux, Céline, Clément-Lacroix, Philippe, Delerive, Philippe, Namour, Florence
Published in BMC musculoskeletal disorders (03.09.2014)
Published in BMC musculoskeletal disorders (03.09.2014)
Get full text
Journal Article
Filgotinib: A Clinical Pharmacology Review
Namour, Florence, Anderson, Kacey, Nelson, Cara, Tasset, Chantal
Published in Clinical pharmacokinetics (01.06.2022)
Published in Clinical pharmacokinetics (01.06.2022)
Get full text
Journal Article
Influence of age and renal impairment on the steady state pharmacokinetics of filgotinib, a selective JAK1 inhibitor
Namour, Florence, Fagard, Liesbeth, Van der Aa, Annegret, Harrison, Pille, Xin, Yan, Tasset, Chantal
Published in British journal of clinical pharmacology (01.12.2018)
Published in British journal of clinical pharmacology (01.12.2018)
Get full text
Journal Article
ISABELA Studies: Plasma Exposure and Target Engagement Do Not Explain the Lack of Efficacy of Ziritaxestat in Patients with Idiopathic Pulmonary Fibrosis
Taneja, Amit, Jentsch, Garrit, Delage, Stéphane, Randall, Matthew J., Blink, Bernt, Bauer, Yasmina, Namour, Florence
Published in Clinical pharmacology and therapeutics (01.03.2024)
Published in Clinical pharmacology and therapeutics (01.03.2024)
Get full text
Journal Article
Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Filgotinib, a Selective JAK‐1 Inhibitor, After Short‐Term Treatment of Rheumatoid Arthritis: Results of Two Randomized Phase IIa Trials
Vanhoutte, Frédéric, Mazur, Minodora, Voloshyn, Oleksandr, Stanislavchuk, Mykola, Van der Aa, Annegret, Namour, Florence, Galien, René, Meuleners, Luc, van 't Klooster, Gerben
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2017)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2017)
Get full text
Journal Article
Population Pharmacokinetic and Pharmacodynamic Analysis of GLPG1690, an Autotaxin Inhibitor, in Healthy Volunteers and Patients with Idiopathic Pulmonary Fibrosis
Taneja, Amit, Desrivot, Julie, Diderichsen, Paul Matthias, Blanqué, Roland, Allamasey, Lisa, Fagard, Liesbeth, Fieuw, Ann, Van der Aar, Ellen, Namour, Florence
Published in Clinical pharmacokinetics (01.09.2019)
Published in Clinical pharmacokinetics (01.09.2019)
Get full text
Journal Article
GLPG1837, a CFTR potentiator, in p.Gly551Asp (G551D)-CF patients: An open-label, single-arm, phase 2a study (SAPHIRA1)
Davies, Jane C, Van de Steen, Olivier, van Koningsbruggen-Rietschel, Silke, Drevinek, Pavel, Derichs, Nico, McKone, Edward F, Kanters, Desirée, Allamassey, Lisa, Namour, Florence, de Kock, Herman, Conrath, Katja
Published in Journal of cystic fibrosis (01.09.2019)
Published in Journal of cystic fibrosis (01.09.2019)
Get full text
Journal Article
GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy
Cozzoli, Anna, Capogrosso, Roberta Francesca, Sblendorio, Valeriana Teresa, Dinardo, Maria Maddalena, Jagerschmidt, Catherine, Namour, Florence, Camerino, Giulia Maria, De Luca, Annamaria
Published in Pharmacological research (01.06.2013)
Published in Pharmacological research (01.06.2013)
Get full text
Journal Article
A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies
Cirkel, Geert A., Kerklaan, Bojana Milojkovic, Vanhoutte, Frédéric, der Aa, Annegret Van, Lorenzon, Giocondo, Namour, Florence, Pujuguet, Philippe, Darquenne, Sophie, de Vos, Filip Y. F., Snijders, Tom J., Voest, Emile E., Schellens, Jan H. M., Lolkema, Martijn P.
Published in Investigational new drugs (01.04.2016)
Published in Investigational new drugs (01.04.2016)
Get full text
Journal Article
Filgotinib, a JAK1 Inhibitor, Has No Effect on QT Interval in Healthy Subjects
Anderson, Kacey, Xin, Yan, Zheng, Hao, Yun, Chohee, Kwan, Ellen, Qin, Ann, Namour, Florence, Kearney, Brian P., Mathias, Anita
Published in Clinical pharmacology in drug development (01.01.2020)
Published in Clinical pharmacology in drug development (01.01.2020)
Get full text
Journal Article