Inhibitors of Melanogenesis: An Updated Review
Pillaiyar, Thanigaimalai, Namasivayam, Vigneshwaran, Manickam, Manoj, Jung, Sang-Hun
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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Journal Article
The Journey of HIV‑1 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) from Lab to Clinic
Namasivayam, Vigneshwaran, Vanangamudi, Murugesan, Kramer, Victor G, Kurup, Sonali, Zhan, Peng, Liu, Xinyong, Kongsted, Jacob, Byrareddy, Siddappa N
Published in Journal of medicinal chemistry (23.05.2019)
Published in Journal of medicinal chemistry (23.05.2019)
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Targeting the Main Protease of SARS‐CoV‐2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors
Breidenbach, Julian, Lemke, Carina, Pillaiyar, Thanigaimalai, Schäkel, Laura, Al Hamwi, Ghazl, Diett, Miriam, Gedschold, Robin, Geiger, Nina, Lopez, Vittoria, Mirza, Salahuddin, Namasivayam, Vigneshwaran, Schiedel, Anke C., Sylvester, Katharina, Thimm, Dominik, Vielmuth, Christin, Phuong Vu, Lan, Zyulina, Maria, Bodem, Jochen, Gütschow, Michael, Müller, Christa E.
Published in Angewandte Chemie International Edition (26.04.2021)
Published in Angewandte Chemie International Edition (26.04.2021)
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HD_BPMDS: a curated binary pattern multitarget dataset of Huntington’s disease–targeting agents
Stefan, Sven Marcel, Pahnke, Jens, Namasivayam, Vigneshwaran
Published in Journal of cheminformatics (17.11.2023)
Published in Journal of cheminformatics (17.11.2023)
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Journal Article
Cancer cells adapt FAM134B/BiP mediated ER-phagy to survive hypoxic stress
Chipurupalli, Sandhya, Ganesan, Raja, Martini, Giulia, Mele, Luigi, Reggio, Alessio, Esposito, Marianna, Kannan, Elango, Namasivayam, Vigneshwaran, Grumati, Paolo, Desiderio, Vincenzo, Robinson, Nirmal
Published in Cell death & disease (18.04.2022)
Published in Cell death & disease (18.04.2022)
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Journal Article
Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359
Hermes, Cornelia, Richarz, René, Wirtz, Daniel A., Patt, Julian, Hanke, Wiebke, Kehraus, Stefan, Voß, Jan Hendrik, Küppers, Jim, Ohbayashi, Tsubasa, Namasivayam, Vigneshwaran, Alenfelder, Judith, Inoue, Asuka, Mergaert, Peter, Gütschow, Michael, Müller, Christa E., Kostenis, Evi, König, Gabriele M., Crüsemann, Max
Published in Nature communications (08.01.2021)
Published in Nature communications (08.01.2021)
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Computer-aided pattern scoring – A multitarget dataset-driven workflow to predict ligands of orphan targets
Stefan, Katja, Namasivayam, Vigneshwaran, Stefan, Sven Marcel
Published in Scientific data (23.05.2024)
Published in Scientific data (23.05.2024)
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Journal Article
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication
Tsukamoto, Yuta, Hiono, Takahiro, Yamada, Shintaro, Matsuno, Keita, Faist, Aileen, Claff, Tobias, Hou, Jianyu, Namasivayam, Vigneshwaran, Vom Hemdt, Anja, Sugimoto, Satoko, Ng, Jin Ying, Christensen, Maria H, Tesfamariam, Yonas M, Wolter, Steven, Juranek, Stefan, Zillinger, Thomas, Bauer, Stefan, Hirokawa, Takatsugu, Schmidt, Florian I, Kochs, Georg, Shimojima, Masayuki, Huang, Yi-Shuian, Pichlmair, Andreas, Kümmerer, Beate M, Sakoda, Yoshihiro, Schlee, Martin, Brunotte, Linda, Müller, Christa E, Igarashi, Manabu, Kato, Hiroki
Published in Science (American Association for the Advancement of Science) (10.02.2023)
Published in Science (American Association for the Advancement of Science) (10.02.2023)
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Journal Article
Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies
Abdelrahman, Aliaa, Namasivayam, Vigneshwaran, Hinz, Sonja, Schiedel, Anke C., Köse, Meryem, Burton, Maggi, El-Tayeb, Ali, Gillard, Michel, Bajorath, Jürgen, de Ryck, Marc, Müller, Christa E.
Published in Biochemical pharmacology (01.02.2017)
Published in Biochemical pharmacology (01.02.2017)
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Journal Article
Ligand binding and activation of UTP-activated G protein-coupled P2Y2 and P2Y4 receptors elucidated by mutagenesis, pharmacological and computational studies
Attah, Isaac Y., Neumann, Alexander, Al-Hroub, Haneen, Rafehi, Muhammad, Baqi, Younis, Namasivayam, Vigneshwaran, Müller, Christa E.
Published in Biochimica et biophysica acta. General subjects (01.03.2020)
Published in Biochimica et biophysica acta. General subjects (01.03.2020)
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Journal Article
Cell‐permeable high‐affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors
Kuschak, Markus, Namasivayam, Vigneshwaran, Rafehi, Muhammad, Voss, Jan H., Garg, Jaspal, Schlegel, Jonathan G., Abdelrahman, Aliaa, Kehraus, Stefan, Reher, Raphael, Küppers, Jim, Sylvester, Katharina, Hinz, Sonja, Matthey, Michaela, Wenzel, Daniela, Fleischmann, Bernd K., Pfeifer, Alexander, Inoue, Asuka, Gütschow, Michael, König, Gabriele M., Müller, Christa E.
Published in British journal of pharmacology (01.04.2020)
Published in British journal of pharmacology (01.04.2020)
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