Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression
Fursova, Nadezda A., Blackledge, Neil P., Nakayama, Manabu, Ito, Shinsuke, Koseki, Yoko, Farcas, Anca M., King, Hamish W., Koseki, Haruhiko, Klose, Robert J.
Published in Molecular cell (06.06.2019)
Published in Molecular cell (06.06.2019)
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PCGF3/5–PRC1 initiates Polycomb recruitment in X chromosome inactivation
Almeida, Mafalda, Pintacuda, Greta, Masui, Osamu, Koseki, Yoko, Gdula, Michal, Cerase, Andrea, Brown, David, Mould, Arne, Innocent, Cassandravictoria, Nakayama, Manabu, Schermelleh, Lothar, Nesterova, Tatyana B., Koseki, Haruhiko, Brockdorff, Neil
Published in Science (American Association for the Advancement of Science) (09.06.2017)
Published in Science (American Association for the Advancement of Science) (09.06.2017)
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A cell competition system with one gene expression from a single-copy gene in one cell
Hasegawa, Yoshinori, Nakano, Megumi, Hosouchi, Tsutomu, Watanabe, Takashi, Yamaguchi, Izumi, Nakayama, Manabu, Ohara, Osamu
Published in PloS one (05.07.2024)
Published in PloS one (05.07.2024)
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Journal Article
PRC1 preserves epidermal tissue integrity independently of PRC2
Cohen, Idan, Zhao, Dejian, Menon, Gopinathan, Nakayama, Manabu, Koseki, Haruhiko, Zheng, Deyou, Ezhkova, Elena
Published in Genes & development (01.01.2019)
Published in Genes & development (01.01.2019)
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Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes
Sugishita, Hiroki, Kondo, Takashi, Ito, Shinsuke, Nakayama, Manabu, Yakushiji-Kaminatsui, Nayuta, Kawakami, Eiryo, Koseki, Yoko, Ohinata, Yasuhide, Sharif, Jafar, Harachi, Mio, Blackledge, Neil P., Klose, Robert J., Koseki, Haruhiko
Published in Nature communications (09.09.2021)
Published in Nature communications (09.09.2021)
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PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes
Endoh, Mitsuhiro, Endo, Takaho A, Shinga, Jun, Hayashi, Katsuhiko, Farcas, Anca, Ma, Kit-Wan, Ito, Shinsuke, Sharif, Jafar, Endoh, Tamie, Onaga, Naoko, Nakayama, Manabu, Ishikura, Tomoyuki, Masui, Osamu, Kessler, Benedikt M, Suda, Toshio, Ohara, Osamu, Okuda, Akihiko, Klose, Robert, Koseki, Haruhiko
Published in eLife (17.03.2017)
Published in eLife (17.03.2017)
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Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity
Tanaka, Shinya, Ise, Wataru, Inoue, Takeshi, Ito, Ayako, Ono, Chisato, Shima, Yoshihito, Sakakibara, Shuhei, Nakayama, Manabu, Fujii, Kentaro, Miura, Ikuo, Sharif, Jafar, Koseki, Haruhiko, Koni, Pandelakis A., Raman, Indu, Li, Quan-Zhen, Kubo, Masato, Fujiki, Katsunori, Nakato, Ryuichiro, Shirahige, Katsuhiko, Araki, Hiromitsu, Miura, Fumihito, Ito, Takashi, Kawakami, Eiryo, Baba, Yoshihiro, Kurosaki, Tomohiro
Published in Nature immunology (01.08.2020)
Published in Nature immunology (01.08.2020)
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MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells
Kojima-Kita, Kanako, Kuramochi-Miyagawa, Satomi, Nakayama, Manabu, Miyata, Haruhiko, Jacobsen, Steven E., Ikawa, Masahito, Koseki, Haruhiko, Nakano, Toru
Published in Scientific reports (14.10.2021)
Published in Scientific reports (14.10.2021)
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Homeostatic pruning and activity of epidermal nerves are dysregulated in barrier-impaired skin during chronic itch development
Takahashi, Sonoko, Ishida, Azusa, Kubo, Akiharu, Kawasaki, Hiroshi, Ochiai, Sotaro, Nakayama, Manabu, Koseki, Haruhiko, Amagai, Masayuki, Okada, Takaharu
Published in Scientific reports (13.06.2019)
Published in Scientific reports (13.06.2019)
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A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
Conway, Eric, Jerman, Emilia, Healy, Evan, Ito, Shinsuke, Holoch, Daniel, Oliviero, Giorgio, Deevy, Orla, Glancy, Eleanor, Fitzpatrick, Darren J., Mucha, Marlena, Watson, Ariane, Rice, Alan M., Chammas, Paul, Huang, Christine, Pratt-Kelly, Indigo, Koseki, Yoko, Nakayama, Manabu, Ishikura, Tomoyuki, Streubel, Gundula, Wynne, Kieran, Hokamp, Karsten, McLysaght, Aoife, Ciferri, Claudio, Di Croce, Luciano, Cagney, Gerard, Margueron, Raphaël, Koseki, Haruhiko, Bracken, Adrian P.
Published in Molecular cell (03.05.2018)
Published in Molecular cell (03.05.2018)
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Human gain-of-function STAT1 mutation disturbs IL-17 immunity in mice
Tamaura, Moe, Satoh-Takayama, Naoko, Tsumura, Miyuki, Sasaki, Takaharu, Goda, Satoshi, Kageyama, Tomoko, Hayakawa, Seiichi, Kimura, Shunsuke, Asano, Takaki, Nakayama, Manabu, Koseki, Haruhiko, Ohara, Osamu, Okada, Satoshi, Ohno, Hiroshi, Kobayashi, Masao
Published in International immunology (12.04.2020)
Published in International immunology (12.04.2020)
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Effects of BMP7 produced by group 2 innate lymphoid cells on adipogenesis
Miyajima, Yurina, Ealey, Kafi N, Motomura, Yasutaka, Mochizuki, Miho, Takeno, Natsuki, Yanagita, Motoko, Economides, Aris N, Nakayama, Manabu, Koseki, Haruhiko, Moro, Kazuyo
Published in International immunology (30.05.2020)
Published in International immunology (30.05.2020)
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Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice
Kon, Ayana, Yamazaki, Satoshi, Nannya, Yasuhito, Kataoka, Keisuke, Ota, Yasunori, Nakagawa, Masahiro Marshall, Yoshida, Kenichi, Shiozawa, Yusuke, Morita, Maiko, Yoshizato, Tetsuichi, Sanada, Masashi, Nakayama, Manabu, Koseki, Haruhiko, Nakauchi, Hiromitsu, Ogawa, Seishi
Published in Blood (08.02.2018)
Published in Blood (08.02.2018)
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Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development
Miyai, Tomohiro, Hojyo, Shintaro, Ikawa, Tomokatsu, Kawamura, Masami, Irié, Tarou, Ogura, Hideki, Hijikata, Atsushi, Bin, Bum-Ho, Yasuda, Takuwa, Kitamura, Hiroshi, Nakayama, Manabu, Ohara, Osamu, Yoshida, Hisahiro, Koseki, Haruhiko, Mishima, Kenji, Fukada, Toshiyuki
Published in Proceedings of the National Academy of Sciences - PNAS (12.08.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (12.08.2014)
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Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies
Tanaka, Tomoyuki, Nakajima-Takagi, Yaeko, Aoyama, Kazumasa, Tara, Shiro, Oshima, Motohiko, Saraya, Atsunori, Koide, Shuhei, Si, Sha, Manabe, Ichiro, Sanada, Masashi, Nakayama, Manabu, Masuko, Masayoshi, Sone, Hirohito, Koseki, Haruhiko, Iwama, Atsushi
Published in The Journal of experimental medicine (02.10.2017)
Published in The Journal of experimental medicine (02.10.2017)
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Critical role of macrophages in the marginal zone in the suppression of immune responses to apoptotic cell-associated antigens
Miyake, Yasunobu, Asano, Kenichi, Kaise, Hitomi, Uemura, Miho, Nakayama, Manabu, Tanaka, Masato
Published in The Journal of clinical investigation (01.08.2007)
Published in The Journal of clinical investigation (01.08.2007)
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Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength
Hojyo, Shintaro, Miyai, Tomohiro, Fujishiro, Hitomi, Kawamura, Masami, Yasuda, Takuwa, Hijikata, Atsushi, Bin, Bum-Ho, Irié, Tarou, Tanaka, Junichi, Atsumi, Toru, Murakami, Masaaki, Nakayama, Manabu, Ohara, Osamu, Himeno, Seiichiro, Yoshida, Hisahiro, Koseki, Haruhiko, Ikawa, Tomokatsu, Mishima, Kenji, Fukada, Toshiyuki
Published in Proceedings of the National Academy of Sciences - PNAS (12.08.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (12.08.2014)
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CBX8, a Polycomb Group Protein, Is Essential for MLL-AF9-Induced Leukemogenesis
Tan, Jiaying, Jones, Morgan, Koseki, Haruhiko, Nakayama, Manabu, Muntean, Andrew G., Maillard, Ivan, Hess, Jay L.
Published in Cancer cell (15.11.2011)
Published in Cancer cell (15.11.2011)
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PLD4 is a genetic determinant to systemic lupus erythematosus and involved in murine autoimmune phenotypes
Akizuki, Shuji, Ishigaki, Kazuyoshi, Kochi, Yuta, Law, Sze-Ming, Matsuo, Keitaro, Ohmura, Koichiro, Suzuki, Akari, Nakayama, Manabu, Iizuka, Yusuke, Koseki, Haruhiko, Ohara, Osamu, Hirata, Jun, Kamatani, Yoichiro, Matsuda, Fumihiko, Sumida, Takayuki, Yamamoto, Kazuhiko, Okada, Yukinori, Mimori, Tsuneyo, Terao, Chikashi
Published in Annals of the rheumatic diseases (01.04.2019)
Published in Annals of the rheumatic diseases (01.04.2019)
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