Genome-wide CRISPR-Cas9 screen identifies rationally designed combination therapies for CRLF2-rearranged Ph-like ALL
Sasaki, Kensuke, Yamauchi, Takuji, Semba, Yuichiro, Nogami, Jumpei, Imanaga, Hiroshi, Terasaki, Tatsuya, Nakao, Fumihiko, Akahane, Koshi, Inukai, Takeshi, Verhoeyen, Els, Akashi, Koichi, Maeda, Takahiro
Published in Blood (03.02.2022)
Published in Blood (03.02.2022)
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Targeting leukemia-specific dependence on the de novo purine synthesis pathway
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Published in Leukemia (01.02.2022)
Published in Leukemia (01.02.2022)
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The XPO7/Npat Axis Inactivation Is a Therapeutic Vulnerability for TP53 -Mutated AML
Semba, Yuichiro, Yamauchi, Takuji, Nakao, Fumihiko, Nogami, Jumpei, Ogawa, Seishi, Maeda, Takahiro, Akashi, Koichi
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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The XPO7/Npat Axis Is a Potential Therapeutic Target for TP53-Mutated AML
Semba, Yuichiro, Yamauchi, Takuji, Nakao, Fumihiko, Nogami, Jumpei, Ogawa, Seishi, Akashi, Koichi, Maeda, Takahiro
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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The RNA helicases DDX19A/B modulate selinexor sensitivity by regulating MCL1 mRNA nuclear export in leukemia cells
Terasaki, Tatsuya, Semba, Yuichiro, Sasaki, Kensuke, Imanaga, Hiroshi, Setoguchi, Kiyoko, Yamauchi, Takuji, Hirabayashi, Shigeki, Nakao, Fumihiko, Akahane, Koshi, Inukai, Takeshi, Sanda, Takaomi, Akashi, Koichi, Maeda, Takahiro
Published in Leukemia (01.09.2024)
Published in Leukemia (01.09.2024)
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Genome-Wide CRISPR/Cas9 Screens Identify DDX19A/DDX19B As a Critical Regulator of Intrinsic Apoptosis By Regulating MCL1 mRNA Cellular Localization
Terasaki, Tatsuya, Semba, Yuichiro, Sasaki, Kensuke, Miyata, Kiyoko, Yamauchi, Takuji, Imanaga, Hiroshi, Nakao, Fumihiko, Hirabayashi, Shigeki, Nogami, Jumpei, Akahane, Koshi, Inukai, Takeshi, Akashi, Koichi, Maeda, Takahiro
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Targeting a mitochondrial E3 ubiquitin ligase complex to overcome AML cell-intrinsic Venetoclax resistance
Nakao, Fumihiko, Setoguchi, Kiyoko, Semba, Yuichiro, Yamauchi, Takuji, Nogami, Jumpei, Sasaki, Kensuke, Imanaga, Hiroshi, Terasaki, Tatsuya, Miyazaki, Manaka, Hirabayashi, Shigeki, Miyawaki, Kohta, Kikushige, Yoshikane, Masuda, Takeshi, Akashi, Koichi, Maeda, Takahiro
Published in Leukemia (01.05.2023)
Published in Leukemia (01.05.2023)
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A Genome-Wide CRISPR-Cas9 Screen Reveals GATOR1 Complex Is a Critical Regulator of Glucocorticoid Sensitivity in B-Cell Precursor Acute Lymphoblastic Leukemia
Imanaga, Hiroshi, Semba, Yuichiro, Sasaki, Kensuke, Miyata, Kiyoko, Yamauchi, Takuji, Terasaki, Tatsuya, Nakao, Fumihiko, Hirabayashi, Shigeki, Nogami, Jumpei, Akashi, Koichi, Maeda, Takahiro
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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