TAS4464, A Highly Potent and Selective Inhibitor of NEDD8-Activating Enzyme, Suppresses Neddylation and Shows Antitumor Activity in Diverse Cancer Models
Yoshimura, Chihoko, Muraoka, Hiromi, Ochiiwa, Hiroaki, Tsuji, Shingo, Hashimoto, Akihiro, Kazuno, Hiromi, Nakagawa, Fumio, Komiya, Yu, Suzuki, Satoshi, Takenaka, Toru, Kumazaki, Masafumi, Fujita, Naoya, Mizutani, Takashi, Ohkubo, Shuichi
Published in Molecular cancer therapeutics (01.07.2019)
Published in Molecular cancer therapeutics (01.07.2019)
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Acquired resistance to trastuzumab/pertuzumab or to T‐DM1 in vivo can be overcome by HER2 kinase inhibition with TAS0728
Irie, Hiroki, Kawabata, Rumi, Fujioka, Yayoi, Nakagawa, Fumio, Itadani, Hiraku, Nagase, Hideki, Ito, Kimihiro, Uchida, Junji, Ohkubo, Shuichi, Matsuo, Kenichi
Published in Cancer science (01.06.2020)
Published in Cancer science (01.06.2020)
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Journal Article
TAS-116 inhibits oncogenic KIT signalling on the Golgi in both imatinib-naïve and imatinib-resistant gastrointestinal stromal tumours
Saito, Yurina, Takahashi, Tsuyoshi, Obata, Yuuki, Nishida, Toshirou, Ohkubo, Shuichi, Nakagawa, Fumio, Serada, Satoshi, Fujimoto, Minoru, Ohkawara, Tomoharu, Nishigaki, Takahiko, Sugase, Takahito, Koh, Masahiro, Ishida, Tomo, Tanaka, Koji, Miyazaki, Yasuhiro, Makino, Tomoki, Kurokawa, Yukinori, Nakajima, Kiyokazu, Yamasaki, Makoto, Hirota, Seiichi, Naka, Tetsuji, Mori, Masaki, Doki, Yuichiro
Published in British journal of cancer (01.03.2020)
Published in British journal of cancer (01.03.2020)
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Journal Article
Activity of TAS4464, a novel NEDD8 activating enzyme E1 inhibitor, against multiple myeloma via inactivation of nuclear factor κB pathways
Muraoka, Hiromi, Yoshimura, Chihoko, Kawabata, Rumi, Tsuji, Shingo, Hashimoto, Akihiro, Ochiiwa, Hiroaki, Nakagawa, Fumio, Fujioka, Yayoi, Matsuo, Kenichi, Ohkubo, Shuichi
Published in Cancer science (01.12.2019)
Published in Cancer science (01.12.2019)
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Aggressive Intraoperative Cisternal Clot Removal After Clipping Aneurismal Subarachnoid Hemorrhage in Elderly Patients
Yoshikane, Tsutomu, Miyazaki, Takeshi, Yasuda, Shinichi, Uchimura, Masahiro, Fujiwara, Yuta, Nakagawa, Fumio, Kambara, Mizuki, Nagai, Hidemasa, Akiyama, Yasuhiko
Published in World neurosurgery (01.03.2021)
Published in World neurosurgery (01.03.2021)
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Effective Sequential Combined Chemotherapy with Trifluridine/Tipiracil and Regorafenib in Human Colorectal Cancer Cells
Matsuoka, Kazuaki, Nakagawa, Fumio, Tanaka, Nozomu, Okabe, Hiroyuki, Matsuo, Kenichi, Takechi, Teiji
Published in International journal of molecular sciences (25.09.2018)
Published in International journal of molecular sciences (25.09.2018)
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A Doppler Flow Analysis of the Neovascular Flow in Carotid Plaque Using Ultrasound Micro-flow Imaging
Fumio NAKAGAWA, Hidemasa NAGAI, Shoko URUSHIMATSU, Yuta FUJIWARA, Mizuki KAMBARA, Tsutomu YOSHIKANE, Takeshi MIYAZAKI, Yasuhiko AKIYAMA
Published in Shimane Journal of Medical Science (01.12.2020)
Published in Shimane Journal of Medical Science (01.12.2020)
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History and Progression of Endovascular Recanalization for the Acute Ischemic Stroke in Japan
Kentaro HAYASHI, Kazuhiro YAMAMOTO, Shun ARITAKE, Satoshi ABE, Mizuki KAMBARA, Fumio NAKAGAWA, Tsutomu YOSHIKANE, Tomohiro YAMASAKI, Yohei SHIBATA, Tatsuya FURUTA, Masahiro UCHIMURA, Yuta FUJIWARA, Hidemasa NAGAI, Yasuhiko AKIYAMA
Published in Shimane Journal of Medical Science (01.09.2021)
Published in Shimane Journal of Medical Science (01.09.2021)
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Modification of TRPV4 activity by acetaminophen
Nakagawa, Fumio, Higashi, Sen, Ando, Eika, Ohsumi, Tomoko, Watanabe, Seiji, Takeuchi, Hiroshi
Published in Heliyon (01.01.2020)
Published in Heliyon (01.01.2020)
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Combined direct and indirect revascularization surgery for pediatric moyamoya disease using plastic surgical techniques
Yoshikane, Tsutomu, Hayashi, Kentaro, Yamamoto, Kazuhiro, Uchimura, Masahiro, Fujiwara, Yuta, Nakagawa, Fumio, Kambara, Mizuki, Nagai, Hidemasa, Akiyama, Yasuhiko
Published in Nervous System in Children (2021)
Published in Nervous System in Children (2021)
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Delayed leukoencephalopathy and subsequent small ischemia after endovascular treatment in a patient with cerebral aneurysm
Shibata, Yohei, Akiyama, Yasuhiko, Nakagawa, Fumio, Kambara, Mizuki, Yamasaki, Tomohiro, Urushimatsu, Shoko, Yoshikane, Tsutomu, Nagai, Hidemasa, Yamamoto, Kazuhiro, Hayashi, Kentaro
Published in Japanese Journal of Stroke (2023)
Published in Japanese Journal of Stroke (2023)
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Delayed leukoencephalopathy and subsequent small ischemia after endovascular treatment in a patient with cerebral aneurysm
Shibata, Yohei, Akiyama, Yasuhiko, Nakagawa, Fumio, Kambara, Mizuki, Yamasaki, Tomohiro, Urushimatsu, Shoko, Yoshikane, Tsutomu, Nagai, Hidemasa, Yamamoto, Kazuhiro, Hayashi, Kentaro
Published in Japanese Journal of Stroke (2022)
Published in Japanese Journal of Stroke (2022)
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A Case of Metastatic Peripheral T-cell Lymphoma of the Central Nervous System During the Perinatal Period
Eda, Hirotake, Miyazaki, Takeshi, Oonishi, Chie, Mitaki, Shingo, Nakagawa, Fumio, Hagiwara, Shinya, Nagai, Hidemasa, Akiyama, Yasuhiko
Published in Nō shinkei geka (01.05.2019)
Published in Nō shinkei geka (01.05.2019)
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Doppler ultrasonography of the ipsilateral vertebral artery with high-grade stenosis of the subclavian artery: a series of 12 cases
NAGAI, Hidemasa, TSUJI, Masahiro, EDA, Hirotake, NAKAGAWA, Fumio, KAMBARA, Mizuki, YOSHIKANE, Tsutomu, HAGIWARA, Shinya, NAKAU, Hiroya, MIYAZAKI, Takeshi, AKIYAMA, Yasuhiko
Published in Neurosonology (2017)
Published in Neurosonology (2017)
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