The E3 ubiquitin-ligase Bmi1/Ring1A controls the proteasomal degradation of Top2alpha cleavage complex - a potentially new drug target
Alchanati, Iris, Teicher, Carmit, Cohen, Galit, Shemesh, Vivian, Barr, Haim M, Nakache, Philippe, Ben-Avraham, Danny, Idelevich, Anna, Angel, Itzchak, Livnah, Nurit, Tuvia, Shmuel, Reiss, Yuval, Taglicht, Daniel, Erez, Omri
Published in PloS one (01.12.2009)
Published in PloS one (01.12.2009)
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Journal Article
Abstract LB-295: Discovery of potent selective oral ACSS2 inhibitors for the treatment of acetate avid tumors
Goutopoulos, Andreas, Erez, Omri, Nakache, Philippe, Alchanati, Iris, Hay-Koren, Avital, Paz, Dikla, Kovalerchik, Dimitri, Oppenheimer, Hannah, Gottlieb, Eyal, Botti, Simone, Mor, Inbal, Pastukh, Nina
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
이미다졸 3-옥시드 유도체 기반의 ACSS2 억제제 및 이의 사용 방법
FINCH HARRY, GOUTOPOULOS ANDREAS, EREZ OMRI, BOTTI SIMONE, NAKACHE PHILIPPE
Year of Publication 26.01.2023
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Year of Publication 26.01.2023
Patent
ACSS2 저해제 및 이의 사용 방법
FINCH HARRY, GOUTOPOULOS ANDREAS, EREZ OMRI, BOTTI SIMONE, NAKACHE PHILIPPE
Year of Publication 03.03.2022
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Year of Publication 03.03.2022
Patent
ACSS2 저해제 및 이의 사용 방법
GOUTOPOULOS ANDREAS, EREZ OMRI, BOTTI SIMONE, LABELLE MARC, NAKACHE PHILIPPE
Year of Publication 24.07.2020
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Year of Publication 24.07.2020
Patent
The E3 Ubiquitin-Ligase Bmi1/Ring1A Controls the Proteasomal Degradation of Top2α Cleavage Complex – A Potentially New Drug Target
Alchanati, Iris, Teicher, Carmit, Cohen, Galit, Shemesh, Vivian, Barr, Haim M., Nakache, Philippe, Ben-Avraham, Danny, Idelevich, Anna, Angel, Itzchak, Livnah, Nurit, Tuvia, Shmuel, Reiss, Yuval, Taglicht, Daniel, Erez, Omri
Published in PloS one (01.12.2009)
Published in PloS one (01.12.2009)
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Journal Article
Abstract 1397: A phenotypic-based drug discovery approach against tumors with MTAP loss
Goutopoulos, Andreas, Amanati, Iris, Hay-Koren, Avital, Fattaey, Ali, Nakache, Philippe, Kovalerchik, Dimitri, Paz, Dikla, Botti, Simone, Oppenheimer, Hanna, Erez, Omri, Fainer, Irit
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Abstract 2326: Preclinical characterization of MTB-9655, a first-in-class, clinical stage ACSS2 inhibitor
Goutopoulos, Andreas, Amanati, Iris, Fattaey, Ali, Hay-Koren, Avital, Nakache, Philippe, Erez, Omri, Kovalerchik, Dimitri, Paz, Dikla, Botti, Simone, Oppenheimer, Hannah, Fainer, Irit
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
The E3 Ubiquitin-Ligase Bmi1/Ring1A Controls the Proteasomal Degradation of Top2[alpha] Cleavage Complex - A Potentially New Drug Target
Alchanati, Iris, Teicher, Carmit, Cohen, Galit, Shemesh, Vivian, Barr, Haim M, Nakache, Philippe, Ben-Avraham, Danny, Idelevich, Anna, Angel, Itzchak, Livnah, Nurit, Tuvia, Shmuel, Reiss, Yuval, Taglicht, Daniel, Erez, Omri
Published in PloS one (01.12.2009)
Published in PloS one (01.12.2009)
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Journal Article
ACSS2-INHIBITORER OG FREMGANGSMÅDER TIL ANVENDELSE DERAF
LABELLE, Marc, EREZ, Omri, BOTTI, Simone, NAKACHE, Philippe, GOUTOPOULOS, Andreas
Year of Publication 09.09.2024
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Year of Publication 09.09.2024
Patent
Acss2 inhibitors and methods of use thereof
Omri Erez, Marc Labelle, Philippe Nakache, Simone Botti, Andreas Goutopoulos
Year of Publication 01.08.2024
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Year of Publication 01.08.2024
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ACSS2 INHIBITORS AND METHODS OF USE THEREOF
LABELLE, Marc, EREZ, Omri, BOTTI, Simone, NAKACHE, Philippe, GOUTOPOULOS, Andreas
Year of Publication 03.07.2024
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Year of Publication 03.07.2024
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IMIDAZOLE 3-OXIDE DERIVATIVE BASED ACSS2 INHIBITORS AND METHODS OF USE THEREOF
EREZ, Omri, BOTTI, Simone, NAKACHE, Philippe, GOUTOPOULOS, Andreas, FINCH, Harry
Year of Publication 12.06.2024
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Year of Publication 12.06.2024
Patent
ACSS2 inhibitors and methods of use thereof
LABELLE, Marc, EREZ, Omri, BOTTI, Simone, NAKACHE, Philippe, GOUTOPOULOS, Andreas
Year of Publication 31.08.2023
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Year of Publication 31.08.2023
Patent
IMIDAZOLE 3-OXIDE DERIVATIVE BASED ACSS2 INHIBITORS AND METHODS OF USE THEREOF
Finch, Harry, EREZ, Omri, BOTTI, Simone, NAKACHE, Philippe, GOUTOPOULOS, Andreas
Year of Publication 08.06.2023
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Year of Publication 08.06.2023
Patent