A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes
Niewczas, Monika A., Pavkov, Meda E., Skupien, Jan, Smiles, Adam, Md Dom, Zaipul I., Wilson, Jonathan M., Park, Jihwan, Nair, Viji, Schlafly, Andrew, Saulnier, Pierre-Jean, Satake, Eiichiro, Simeone, Christopher A., Shah, Hetal, Qiu, Chengxiang, Looker, Helen C., Fiorina, Paolo, Ware, Carl F., Sun, Jennifer K., Doria, Alessandro, Kretzler, Matthias, Susztak, Katalin, Duffin, Kevin L., Nelson, Robert G., Krolewski, Andrzej S.
Published in Nature medicine (01.05.2019)
Published in Nature medicine (01.05.2019)
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Journal Article
ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes
Ducasa, G Michelle, Mitrofanova, Alla, Mallela, Shamroop K, Liu, Xiaochen, Molina, Judith, Sloan, Alexis, Pedigo, Christopher E, Ge, Mengyuan, Santos, Javier Varona, Hernandez, Yanio, Kim, Jin-Ju, Maugeais, Cyrille, Mendez, Armando J, Nair, Viji, Kretzler, Matthias, Burke, George W, Nelson, Robert G, Ishimoto, Yu, Inagi, Reiko, Banerjee, Santanu, Liu, Shaoyi, Szeto, Hazel H, Merscher, Sandra, Fontanesi, Flavia, Fornoni, Alessia
Published in The Journal of clinical investigation (01.08.2019)
Published in The Journal of clinical investigation (01.08.2019)
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Journal Article
Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker
Ju, Wenjun, Nair, Viji, Smith, Shahaan, Zhu, Li, Shedden, Kerby, Song, Peter X K, Mariani, Laura H, Eichinger, Felix H, Berthier, Celine C, Randolph, Ann, Lai, Jennifer Yi-Chun, Zhou, Yan, Hawkins, Jennifer J, Bitzer, Markus, Sampson, Matthew G, Thier, Martina, Solier, Corinne, Duran-Pacheco, Gonzalo C, Duchateau-Nguyen, Guillemette, Essioux, Laurent, Schott, Brigitte, Formentini, Ivan, Magnone, Maria C, Bobadilla, Maria, Cohen, Clemens D, Bagnasco, Serena M, Barisoni, Laura, Lv, Jicheng, Zhang, Hong, Wang, Hai-Yan, Brosius, Frank C, Gadegbeku, Crystal A, Kretzler, Matthias
Published in Science translational medicine (02.12.2015)
Published in Science translational medicine (02.12.2015)
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Journal Article
Growth Differentiation Factor-15 and Risk of CKD Progression
Nair, Viji, Robinson-Cohen, Cassianne, Smith, Michelle R, Bellovich, Keith A, Bhat, Zeenat Yousuf, Bobadilla, Maria, Brosius, Frank, de Boer, Ian H, Essioux, Laurent, Formentini, Ivan, Gadegbeku, Crystal A, Gipson, Debbie, Hawkins, Jennifer, Himmelfarb, Jonathan, Kestenbaum, Bryan, Kretzler, Matthias, Magnone, Maria Chiara, Perumal, Kalyani, Steigerwalt, Susan, Ju, Wenjun, Bansal, Nisha
Published in Journal of the American Society of Nephrology (01.07.2017)
Published in Journal of the American Society of Nephrology (01.07.2017)
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Journal Article
Shared and distinct lipid-lipid interactions in plasma and affected tissues in a diabetic mouse model
Sas, Kelli M., Lin, Jiahe, Rajendiran, Thekkelnaycke M., Soni, Tanu, Nair, Viji, Hinder, Lucy M., Jagadish, Hosagrahar V., Gardner, Thomas W., Abcouwer, Steven F., Brosius, Frank C., Feldman, Eva L., Kretzler, Matthias, Michailidis, George, Pennathur, Subramaniam
Published in Journal of lipid research (01.02.2018)
Published in Journal of lipid research (01.02.2018)
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Journal Article
SGLT2 inhibitors mitigate kidney tubular metabolic and mTORC1 perturbations in youth-onset type 2 diabetes
Schaub, Jennifer A, AlAkwaa, Fadhl M, McCown, Phillip J, Naik, Abhijit S, Nair, Viji, Eddy, Sean, Menon, Rajasree, Otto, Edgar A, Demeke, Dawit, Hartman, John, Fermin, Damian, O'Connor, Christopher L, Subramanian, Lalita, Bitzer, Markus, Harned, Roger, Ladd, Patricia, Pyle, Laura, Pennathur, Subramaniam, Inoki, Ken, Hodgin, Jeffrey B, Brosius, 3rd, Frank C, Nelson, Robert G, Kretzler, Matthias, Bjornstad, Petter
Published in The Journal of clinical investigation (01.03.2023)
Published in The Journal of clinical investigation (01.03.2023)
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Journal Article
Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis
Berthier, Celine C, Bethunaickan, Ramalingam, Gonzalez-Rivera, Tania, Nair, Viji, Ramanujam, Meera, Zhang, Weijia, Bottinger, Erwin P, Segerer, Stephan, Lindenmeyer, Maja, Cohen, Clemens D, Davidson, Anne, Kretzler, Matthias
Published in The Journal of immunology (1950) (15.07.2012)
Published in The Journal of immunology (1950) (15.07.2012)
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Journal Article
Podocyte-specific JAK2 overexpression worsens diabetic kidney disease in mice
Zhang, Hongyu, Nair, Viji, Saha, Jharna, Atkins, Kevin B., Hodgin, Jeffrey B., Saunders, Thomas L., Myers, Martin G., Werner, Thomas, Kretzler, Matthias, Brosius, Frank C.
Published in Kidney international (01.10.2017)
Published in Kidney international (01.10.2017)
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Journal Article
Molecular Characterization of Membranous Nephropathy
Sealfon, Rachel, Mariani, Laura, Avila-Casado, Carmen, Nair, Viji, Menon, Rajasree, Funk, Julien, Wong, Aaron, Lerner, Gabriel, Hayashi, Norifumi, Troyanskaya, Olga, Kretzler, Matthias, Beck, Jr, Laurence H
Published in Journal of the American Society of Nephrology (01.06.2022)
Published in Journal of the American Society of Nephrology (01.06.2022)
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Journal Article
Defining cell-type specificity at the transcriptional level in human disease
Ju, Wenjun, Greene, Casey S, Eichinger, Felix, Nair, Viji, Hodgin, Jeffrey B, Bitzer, Markus, Lee, Young-Suk, Zhu, Qian, Kehata, Masami, Li, Min, Jiang, Song, Rastaldi, Maria Pia, Cohen, Clemens D, Troyanskaya, Olga G, Kretzler, Matthias
Published in Genome research (01.11.2013)
Published in Genome research (01.11.2013)
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Journal Article
Identification of Cross-Species Shared Transcriptional Networks of Diabetic Nephropathy in Human and Mouse Glomeruli
HODGIN, Jeffrey B, NAIR, Viji, KRETZLER, Matthias, HONGYU ZHANG, RANDOLPH, Ann, HARRIS, Raymond C, NELSON, Robert G, JENNIFER WEIL, E, CAVALCOLI, James D, PATEL, Jignesh M, BROSIUS, Frank C
Published in Diabetes (New York, N.Y.) (01.01.2013)
Published in Diabetes (New York, N.Y.) (01.01.2013)
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Journal Article
A molecular morphometric approach to diabetic kidney disease can link structure to function and outcome
Nair, Viji, Komorowsky, Claudiu V., Weil, E. Jennifer, Yee, Berne, Hodgin, Jeffrey, Harder, Jennifer L., Godfrey, Bradley, Ju, Wenjun, Boustany-Kari, Carine M., Schwarz, Margrit, Lemley, Kevin V., Nelson, Peter J., Nelson, Robert G., Kretzler, Matthias
Published in Kidney international (01.02.2018)
Published in Kidney international (01.02.2018)
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Journal Article
FSGS as an Adaptive Response to Growth-Induced Podocyte Stress
Nishizono, Ryuzoh, Kikuchi, Masao, Wang, Su Q, Chowdhury, Mahboob, Nair, Viji, Hartman, John, Fukuda, Akihiro, Wickman, Larysa, Hodgin, Jeffrey B, Bitzer, Markus, Naik, Abhijit, Wiggins, Jocelyn, Kretzler, Matthias, Wiggins, Roger C
Published in Journal of the American Society of Nephrology (01.10.2017)
Published in Journal of the American Society of Nephrology (01.10.2017)
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Journal Article
IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes
Lay, Abigail C., Hale, Lorna J., Stowell-Connolly, Holly, Pope, Robert J. P., Nair, Viji, Ju, Wenjun, Marquez, Eva, Rollason, Ruth, Hurcombe, Jenny A., Hayes, Bryony, Roberts, Timothy, Gillam, Lawrence, Allington, Jonathan, Nelson, Robert G., Kretzler, Matthias, Holly, Jeff M. P., Perks, Claire M., McArdle, Craig A., Welsh, Gavin I., Coward, Richard J. M.
Published in Diabetologia (01.07.2021)
Published in Diabetologia (01.07.2021)
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Journal Article
Cyclodextrin Protects Podocytes in Diabetic Kidney Disease
MERSCHER-GOMEZ, Sandra, GUZMAN, Johanna, MAIGUEL, Dony, JOHNSON, Kevin, GOLDBERG, Ronald, NAIR, Viji, RANDOLPH, Ann, KRETZLER, Matthias, NELSON, Robert G, BURKE, George W, GROOP, Per-Henrik, FORNONI, Alessia, PEDIGO, Christopher E, LEHTO, Markku, AGUILLON-PRADA, Robier, MENDEZ, Armando, LASSENIUS, Mariann I, FORSBLOM, Carol, TAEHYUN YOO, VILLARREAL, Rodrigo
Published in Diabetes (New York, N.Y.) (01.11.2013)
Published in Diabetes (New York, N.Y.) (01.11.2013)
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Journal Article
Identification of glomerular and podocyte-specific genes and pathways activated by sera of patients with focal segmental glomerulosclerosis
Otalora, Lilian, Chavez, Efren, Watford, Daniel, Tueros, Lissett, Correa, Mayrin, Nair, Viji, Ruiz, Philip, Wahl, Patricia, Eddy, Sean, Martini, Sebastian, Kretzler, Matthias, Burke, 3rd, George W, Fornoni, Alessia, Merscher, Sandra
Published in PloS one (03.10.2019)
Published in PloS one (03.10.2019)
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Journal Article
ORAI channels are critical for receptor-mediated endocytosis of albumin
Zeng, Bo, Chen, Gui-Lan, Garcia-Vaz, Eliana, Bhandari, Sunil, Daskoulidou, Nikoleta, Berglund, Lisa M., Jiang, Hongni, Hallett, Thomas, Zhou, Lu-Ping, Huang, Li, Xu, Zi-Hao, Nair, Viji, Nelson, Robert G., Ju, Wenjun, Kretzler, Matthias, Atkin, Stephen L., Gomez, Maria F., Xu, Shang-Zhong
Published in Nature communications (04.12.2017)
Published in Nature communications (04.12.2017)
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Journal Article
Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease
Smyth, Laura J., Dahlström, Emma H., Syreeni, Anna, Kerr, Katie, Kilner, Jill, Doyle, Ross, Brennan, Eoin, Nair, Viji, Fermin, Damian, Nelson, Robert G., Looker, Helen C., Wooster, Christopher, Andrews, Darrell, Anderson, Kerry, McKay, Gareth J., Cole, Joanne B., Salem, Rany M., Conlon, Peter J., Kretzler, Matthias, Hirschhorn, Joel N., Sadlier, Denise, Godson, Catherine, Florez, Jose C., Forsblom, Carol, Maxwell, Alexander P., Groop, Per-Henrik, Sandholm, Niina, McKnight, Amy Jayne
Published in Nature communications (22.12.2022)
Published in Nature communications (22.12.2022)
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Journal Article
Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications
Sas, Kelli M, Kayampilly, Pradeep, Byun, Jaeman, Nair, Viji, Hinder, Lucy M, Hur, Junguk, Zhang, Hongyu, Lin, Chengmao, Qi, Nathan R, Michailidis, George, Groop, Per-Henrik, Nelson, Robert G, Darshi, Manjula, Sharma, Kumar, Schelling, Jeffrey R, Sedor, John R, Pop-Busui, Rodica, Weinberg, Joel M, Soleimanpour, Scott A, Abcouwer, Steven F, Gardner, Thomas W, Burant, Charles F, Feldman, Eva L, Kretzler, Matthias, Brosius, 3rd, Frank C, Pennathur, Subramaniam
Published in JCI insight (22.09.2016)
Published in JCI insight (22.09.2016)
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Journal Article
Renin-angiotensin system inhibition reverses the altered triacylglycerol metabolic network in diabetic kidney disease
Sas, Kelli M., Lin, Jiahe, Wang, Chih-Hong, Zhang, Hongyu, Saha, Jharna, Rajendiran, Thekkelnaycke M., Soni, Tanu, Nair, Viji, Eichinger, Felix, Kretzler, Matthias, Brosius, Frank C., Michailidis, George, Pennathur, Subramaniam
Published in Metabolomics (01.07.2021)
Published in Metabolomics (01.07.2021)
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