M2‐like macrophage polarization in high lactic acid‐producing head and neck cancer
Ohashi, Toshimitsu, Aoki, Mitsuhiro, Tomita, Hiroyuki, Akazawa, Takashi, Sato, Katsuya, Kuze, Bunya, Mizuta, Keisuke, Hara, Akira, Nagaoka, Hitoshi, Inoue, Norimitsu, Ito, Yatsuji
Published in Cancer science (01.06.2017)
Published in Cancer science (01.06.2017)
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Journal Article
Critical Roles of Activation-Induced Cytidine Deaminase in the Homeostasis of Gut Flora
Fagarasan, Sidonia, Muramatsu, Masamichi, Suzuki, Keiichiro, Nagaoka, Hitoshi, Hiai, Hiroshi, Honjo, Tasuku
Published in Science (American Association for the Advancement of Science) (15.11.2002)
Published in Science (American Association for the Advancement of Science) (15.11.2002)
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Journal Article
DBS is activated by EPHB2/SRC signaling-mediated tyrosine phosphorylation in HEK293 cells
Nakano, Shun, Nishikawa, Masashi, Asaoka, Rina, Ishikawa, Natsuko, Ohwaki, Chisato, Sato, Katsuya, Nagaoka, Hitoshi, Yamakawa, Hisashi, Nagase, Takahiro, Ueda, Hiroshi
Published in Molecular and cellular biochemistry (01.09.2019)
Published in Molecular and cellular biochemistry (01.09.2019)
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Journal Article
B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
Honjo, Tasuku, Tran, Thinh Huy, Nakata, Mikiyo, Suzuki, Keiichiro, Begum, Nasim A, Shinkura, Reiko, Fagarasan, Sidonia, Nagaoka, Hitoshi
Published in Nature immunology (01.02.2010)
Published in Nature immunology (01.02.2010)
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Journal Article
The circulating immunoglobulins negatively impact on the parasite clearance in the liver of Leishmania donovani-infected mice via dampening ROS activity
Srinontong, Piyarat, Wu, Zhiliang, Sato, Katsuya, Nagaoka, Hitoshi, Maekawa, Yoichi
Published in Biochemical and biophysical research communications (17.11.2018)
Published in Biochemical and biophysical research communications (17.11.2018)
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Journal Article
Activation-Induced Cytidine Deaminase Shuttles between Nucleus and Cytoplasm like Apolipoprotein B mRNA Editing Catalytic Polypeptide 1
Ito, Satomi, Nagaoka, Hitoshi, Shinkura, Reiko, Begum, Nasim, Muramatsu, Masamichi, Nakata, Mikiyo, Honjo, Tasuku
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2004)
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Journal Article
AID Enzyme-Induced Hypermutation in an Actively Transcribed Gene in Fibroblasts
Yoshikawa, Kiyotsugu, Okazaki, Il-mi, Eto, Tomonori, Kinoshita, Kazuo, Muramatsu, Masamichi, Nagaoka, Hitoshi, Honjo, Tasuku
Published in Science (American Association for the Advancement of Science) (14.06.2002)
Published in Science (American Association for the Advancement of Science) (14.06.2002)
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Journal Article
Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age
Qin, Hongyan, Suzuki, Keiichiro, Nakata, Mikiyo, Chikuma, Shunsuke, Izumi, Nakako, Huong, Le Thi, Maruya, Mikako, Fagarasan, Sidonia, Busslinger, Meinrad, Honjo, Tasuku, Nagaoka, Hitoshi
Published in PloS one (28.12.2011)
Published in PloS one (28.12.2011)
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Journal Article
Separate domains of AID are required for somatic hypermutation and class-switch recombination
Honjo, Tasuku, Shinkura, Reiko, Ito, Satomi, Begum, Nasim A, Nagaoka, Hitoshi, Muramatsu, Masamichi, Kinoshita, Kazuo, Sakakibara, Yoshimasa, Hijikata, Hiroko
Published in Nature immunology (01.07.2004)
Published in Nature immunology (01.07.2004)
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Journal Article
Discovery of Activation‐Induced Cytidine Deaminase, the Engraver of Antibody Memory
Muramatsu, Masamichi, Nagaoka, Hitoshi, Shinkura, Reiko, Begum, Nasim A., Honjo, Tasuku
Published in AID for Immunoglobulin Diversity (2007)
Published in AID for Immunoglobulin Diversity (2007)
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Book Chapter
Journal Article
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
Kotani, Ai, Kakazu, Naoki, Tsuruyama, Tatsuaki, Okazaki, Il-mi, Muramatsu, Masamichi, Kinoshita, Kazuo, Nagaoka, Hitoshi, Yabe, Daisuke, Honjo, Tasuku
Published in Proceedings of the National Academy of Sciences - PNAS (30.01.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (30.01.2007)
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Journal Article
Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID
Wakae, Koshou, Magor, Brad G., Saunders, Holly, Nagaoka, Hitoshi, Kawamura, Akemi, Kinoshita, Kazuo, Honjo, Tasuku, Muramatsu, Masamichi
Published in International immunology (01.01.2006)
Published in International immunology (01.01.2006)
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Journal Article
Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity
Nagaoka, Hitoshi, Tran, Thinh Huy, Kobayashi, Maki, Aida, Masatoshi, Honjo, Tasuku
Published in International immunology (01.04.2010)
Published in International immunology (01.04.2010)
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Journal Article
AID to overcome the limitations of genomic information
Honjo, Tasuku, Nagaoka, Hitoshi, Shinkura, Reiko, Muramatsu, Masamichi
Published in Nature Immunology (01.07.2005)
Published in Nature Immunology (01.07.2005)
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Journal Article
C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
Doi, Tomomitsu, Kato, Lucia, Ito, Satomi, Shinkura, Reiko, Wei, Min, Nagaoka, Hitoshi, Wang, Jishu, Honjo, Tasuku
Published in Proceedings of the National Academy of Sciences - PNAS (24.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (24.02.2009)
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Journal Article
In vivo analysis of Aicda gene regulation: a critical balance between upstream enhancers and intronic silencers governs appropriate expression
Huong, Le Thi, Kobayashi, Maki, Nakata, Mikiyo, Shioi, Go, Miyachi, Hitoshi, Honjo, Tasuku, Nagaoka, Hitoshi
Published in PloS one (16.04.2013)
Published in PloS one (16.04.2013)
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Journal Article
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
Kobayashi, Maki, Aida, Masatoshi, Nagaoka, Hitoshi, Begum, Nasim A, Kitawaki, Yoko, Nakata, Mikiyo, Stanlie, Andre, Doi, Tomomitsu, Kato, Lucia, Okazaki, Il-mi, Shinkura, Reiko, Muramatsu, Masamichi, Kinoshita, Kazuo, Honjo, Tasuku
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2009)
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Journal Article
Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation
Okazaki, Il-mi, Okawa, Katsuya, Kobayashi, Maki, Yoshikawa, Kiyotsugu, Kawamoto, Shimpei, Nagaoka, Hitoshi, Shinkura, Reiko, Kitawaki, Yoko, Taniguchi, Hisaaki, Natsume, Tohru, Iemura, Shun-Ichiro, Honjo, Tasuku
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2011)
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Journal Article
Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes
Sabouri, Zahra, Okazaki, Il-mi, Shinkura, Reiko, Begum, Nasim, Nagaoka, Hitoshi, Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Honjo, Tasuku
Published in International immunology (01.08.2009)
Published in International immunology (01.08.2009)
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Journal Article
Further Evidence for Involvement of a Noncanonical Function of Uracil DNA Glycosylase in Class Switch Recombination
Begum, Nasim A., Stanlie, Andre, Doi, Tomomitsu, Sasaki, Yoko, Jin, Hai Wei, Kim, Yong Sung, Nagaoka, Hitoshi, Honjo, Tasuku
Published in Proceedings of the National Academy of Sciences - PNAS (24.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (24.02.2009)
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Journal Article