A Dual-Acting Nitric Oxide Donor and Phosphodiesterase 5 Inhibitor Activates Autophagy in Primary Skin Fibroblasts
Martínez-Martínez, Esther, Atzei, Paola, Vionnet, Christine, Roubaty, Carole, Kaeser-Pebernard, Stephanie, Naef, Reto, Dengjel, Jörn
Published in International journal of molecular sciences (20.06.2022)
Published in International journal of molecular sciences (20.06.2022)
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Journal Article
Impact of office layout on communication in a science-driven business
Boutellier, Roman, Ullman, Fredrik, Schreiber, Jürg, Naef, Reto
Published in R & D management (01.09.2008)
Published in R & D management (01.09.2008)
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Journal Article
Topical Wound Treatment with a Nitric Oxide-Releasing PDE5 Inhibitor Formulation Enhances Blood Perfusion and Promotes Healing in Mice
Ben-Yehuda Greenwald, Maya, Liu, Yu-Hang, Li, Weiye, Hiebert, Paul, Zubair, Maria, Tenor, Hermann, Braun, Tobias, Naef, Reto, Razansky, Daniel, Werner, Sabine
Published in Pharmaceutics (31.10.2022)
Published in Pharmaceutics (31.10.2022)
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Journal Article
Formulation and dermal delivery of a new active pharmaceutical ingredient in an in vitro wound model for the treatment of chronic ulcers
Thormann, Ursula, Marti, Selina, Lensmith, Elizabeth, Lanz, Michael, Herzig, Susanne, Naef, Reto, Imanidis, Georgios
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2024)
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2024)
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Journal Article
Potent and selective xanthine-based inhibitors of phosphodiesterase 5
Arnold, Nichola J., Arnold, Ruth, Beer, David, Bhalay, Gurdip, Collingwood, Stephen P., Craig, Sarah, Devereux, Nicholas, Dodds, Mark, Dunstan, Andrew R., Fairhurst, Robin A., Farr, David, Fullerton, Joseph D., Glen, Angela, Gomez, Sylvie, Haberthuer, Sandra, Hatto, Julia D.I., Howes, Colin, Jones, Darryl, Keller, Thomas H., Leuenberger, Beate, Moser, Heinz E., Muller, Irene, Naef, Reto, Nicklin, Paul A., Sandham, David A., Turner, Katharine L., Tweed, Morris F., Watson, Simon J., Zurini, Mauro
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
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Journal Article
A Dual-Acting Nitric Oxide Donor and Phosphodiesterase 5 Inhibitor Promotes Wound Healing in Normal Mice and Mice with Diabetes
Ben-Yehuda Greenwald, Maya, Tacconi, Carlotta, Jukic, Marko, Joshi, Natasha, Hiebert, Paul, Brinckmann, Jürgen, Tenor, Hermann, Naef, Reto, Werner, Sabine
Published in Journal of investigative dermatology (01.02.2021)
Published in Journal of investigative dermatology (01.02.2021)
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Journal Article
Bifunctional Sildenafil Diazeniumdiolates Acting as Phosphodiesterase 5 Inhibitors and Nitric Oxide Donors− Towards Wound Healing
Mas‐Roselló, Josep, Tenor, Hermann, Szabo, Timea, Naef, Reto, Sieber, Simon, Gademann, Karl
Published in Chembiochem : a European journal of chemical biology (16.04.2024)
Published in Chembiochem : a European journal of chemical biology (16.04.2024)
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Journal Article
TRANSDERMAL DOSAGE FORM, FOR PROMOTING LOCAL BLOOD FLOW, OF DUAL-ACTING PDE5 INHIBITOR/ORGANIC NITRATE ESTER
NAEF, Reto, FRANCISCO, Rita, ATZEI, Paola, JUNG, Hyungil, KIM, Youseong
Year of Publication 07.09.2023
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Year of Publication 07.09.2023
Patent
Dual-Acting Nitric Oxide Donor and Phosphodiesterase Inhibitor TOP-N53 Increases Lifespan and Health Span of Caenorhabditis elegans
Rudgalvyte, Martina, Atzei, Paola, de Brito Francisco, Rita, Naef, Reto, Glauser, Dominique A
Published in microPublication biology (2024)
Published in microPublication biology (2024)
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Journal Article
Alkylation of amino acids without loss of the optical activity: preparation of .alpha.-substituted proline derivatives. A case of self-reproduction of chirality
Seebach, Dieter, Boes, Michael, Naef, Reto, Schweizer, W. Bernd
Published in Journal of the American Chemical Society (01.08.1983)
Published in Journal of the American Chemical Society (01.08.1983)
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Journal Article
가용성 구아닐레이트 사이클라제 활성제 및 포스포디에스테라제 억제제의 신규한 이중 작용 방식 및 이의 용도
DI MAIO SELENA, SPOERRI MICHAEL, TENOR HERMANN, LONE ESRA, KOCH GUIDO, PETERKE JEANETTE, NAEF RETO, MARTINI ELIA
Year of Publication 05.08.2021
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Year of Publication 05.08.2021
Patent