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Dyck, Jason R.B, Cheng, Jie-Fei, Stanley, William C, Barr, Rick, Chandler, Margaret P, Brown, Steven, Wallace, David, Arrhenius, Thomas, Harmon, Charles, Yang, Guang, Nadzan, Alex M, Lopaschuk, Gary D
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Published in Circulation research (14.05.2004)
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Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
Mukherjee, Ranjan, Davies, Peter J. A, Crombie, Diane L, Bischoff, Eric D, Cesario, Rosemary M, Jow, Lily, Hamann, Lawrence G, Boehm, Marcus F, Mondon, Carl E, Nadzan, Alex M, Paterniti, James R, Heyman, Richard A
Published in Nature (London) (27.03.1997)
Published in Nature (London) (27.03.1997)
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Discovery of Potent and Orally Available Malonyl-CoA Decarboxylase Inhibitors as Cardioprotective Agents
Cheng, Jie-Fei, Huang, Yujin, Penuliar, Richard, Nishimoto, Masahiro, Liu, Larry, Arrhenius, Thomas, Yang, Guang, O'Leary, Eoin, Barbosa, Miguel, Barr, Rick, Dyck, Jason R. B, Lopaschuk, Gary D, Nadzan, Alex M
Published in Journal of medicinal chemistry (13.07.2006)
Published in Journal of medicinal chemistry (13.07.2006)
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Synthesis and Structure−Activity Relationship of Small-Molecule Malonyl Coenzyme A Decarboxylase Inhibitors
Cheng, Jie-Fei, Chen, Mi, Wallace, David, Tith, Souvothy, Haramura, Masayuki, Liu, Bin, Mak, Chi Ching, Arrhenius, Thomas, Reily, Sean, Brown, Steven, Thorn, Vicki, Harmon, Charles, Barr, Rick, Dyck, Jason R. B, Lopaschuk, Gary D, Nadzan, Alex M
Published in Journal of medicinal chemistry (09.03.2006)
Published in Journal of medicinal chemistry (09.03.2006)
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Design and Synthesis of Potent Retinoid X Receptor Selective Ligands That Induce Apoptosis in Leukemia Cells
Boehm, Marcus F, Zhang, Lin, Zhi, Lin, McClurg, Michael R, Berger, Elain, Wagoner, Murriel, Mais, Dale E, Suto, Carla M, Davies, Peter J. A, Heyman, Richard A, Nadzan, Alex M
Published in Journal of medicinal chemistry (01.08.1995)
Published in Journal of medicinal chemistry (01.08.1995)
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Matrix Metalloproteinase Inhibitors: A Structure−Activity Study
Levy, Daniel E, Lapierre, France, Liang, Weisheng, Ye, Wenqing, Lange, Christopher W, Li, Xiaoyuan, Grobelny, Damian, Casabonne, Marie, Tyrrell, David, Holme, Kevin, Nadzan, Alex, Galardy, Richard E
Published in Journal of medicinal chemistry (15.01.1998)
Published in Journal of medicinal chemistry (15.01.1998)
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Activation of specific RXR heterodimers by an antagonist of RXR homodimers
Lala, Deepak S, Mukherjee, Ranjan, Schulman, Ira G, Koch, Stacie S. Canan, Dardashti, Laura J, Nadzan, Alex M, Croston, Glenn E, Evans, Ronald M, Heyman, Richard A
Published in Nature (London) (03.10.1996)
Published in Nature (London) (03.10.1996)
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Heteroaryl substituted bis-trifluoromethyl carbinols as malonyl-CoA decarboxylase inhibitors
Cheng, Jie-Fei, Mak, Chi Ching, Huang, Yujin, Penuliar, Richard, Nishimoto, Masahiro, Zhang, Lin, Chen, Mi, Wallace, David, Arrhenius, Thomas, Chu, Donald, Yang, Guang, Barbosa, Miguel, Barr, Rick, Dyck, Jason R.B., Lopaschuk, Gary D., Nadzan, Alex M.
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
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Design and synthesis of heterocyclic malonyl-CoA decarboxylase inhibitors
Cheng, Jie-Fei, Chen, Mi, Liu, Bin, Hou, Zheng, Arrhenius, Thomas, Nadzan, Alex M.
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
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Aza-retinoids as novel retinoid X receptor-specific agonists
Farmer, Luc J., Marron, Kristen S., Canan Koch, Stacie S., Hwang, C.K., Kallel, E Adam, Zhi, Lin, Nadzan, Alex M., Robertson, Dave W., Bennani, Youssef L.
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
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Synthesis of Retinoid X Receptor-Specific Ligands That Are Potent Inducers of Adipogenesis in 3T3-L1 Cells
Canan Koch, Stacie S, Dardashti, Laura J, Cesario, Rosemary M, Croston, Glenn E, Boehm, Marcus F, Heyman, Richard A, Nadzan, Alex M
Published in Journal of medicinal chemistry (25.02.1999)
Published in Journal of medicinal chemistry (25.02.1999)
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Retinoic acid receptor ligands based on the 6-cyclopropyl-2,4-hexadienoic acid
Farmer, Luc J., Zhi, Lin, Jeong, Susan, Lamph, William W., Osburn, Deborah L., Croston, Glenn, Flatten, Karen S., Heyman, Rich A., Nadzan, Alex M.
Published in Bioorganic & medicinal chemistry letters (20.01.2003)
Published in Bioorganic & medicinal chemistry letters (20.01.2003)
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Identification of the First Retinoid X Receptor Homodimer Antagonist
Canan Koch, Stacie S, Dardashti, Laura J, Hebert, Jonathan J, White, Steven K, Croston, Glenn E, Flatten, Karen S, Heyman, Richard A, Nadzan, Alex M
Published in Journal of medicinal chemistry (16.08.1996)
Published in Journal of medicinal chemistry (16.08.1996)
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Expression, purification, and characterization of human malonyl-CoA decarboxylase
Zhou, Demin, Yuen, Phoebe, Chu, Donald, Thon, Vicki, McConnell, Steve, Brown, Steven, Tsang, Andria, Pena, Michael, Russell, Anna, Cheng, Jie-Fei, Nadzan, Alex M., Barbosa, Miguel S., Dyck, Jason R.B., Lopaschuk, Gary D., Yang, Guang
Published in Protein expression and purification (01.04.2004)
Published in Protein expression and purification (01.04.2004)
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A novel retinoic acid receptor-selective retinoid, ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice
SHALINSKY, D. R, BISCHOFF, E. D, LAMPH, W. W, ZHANG, L, BOEHM, M. F, DAVIES, P. J. A, NADZAN, A. M, HEYMAN, R. A
Published in Cancer research (Chicago, Ill.) (1997)
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Published in Cancer research (Chicago, Ill.) (1997)
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Discovery of Novel Retinoic Acid Receptor Agonists Having Potent Antiproliferative Activity in Cervical Cancer Cells
Zhang, Lin, Nadzan, Alex M, Heyman, Richard A, Love, Deborah L, Mais, Dale E, Croston, Glenn, Lamph, William W, Boehm, Marcus F
Published in Journal of medicinal chemistry (05.07.1996)
Published in Journal of medicinal chemistry (05.07.1996)
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Synthesis and Characterization of a Highly Potent and Selective Isotopically Labeled Retinoic Acid Receptor Ligand, ALRT1550
Bennani, Youssef L, Marron, Kristin S, Mais, Dale E, Flatten, Karen, Nadzan, Alex M, Boehm, Marcus F
Published in Journal of organic chemistry (06.02.1998)
Published in Journal of organic chemistry (06.02.1998)
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